The Plasma Vitamin C and E Status in Type II Diabetes with Malaria in Owerri, Nigeria
Abstract:
The plasma vitamin C and E in type II diabetes with malaria were investigated. Eighty confirmed type II diabetes with malaria aged 45-65 years were selected for the study. Sixty normal subjects free from diabetes and malaria were used as control. The levels of plasma vitamin C and E in type II diabetes with malaria were significantly decreased (60.42± 3.7 mmol/L and 8.61±1.12 mg/L respectively) when compared with the control (76.29±9.10 mmol/L and 12.13±1.54 mg/L) (p<0.05). This shows that plasma vitamin C and E are depleted in type II diabetes with malaria. Therefore, there could be an immense benefit in eating foods rich in Vitamin C and E.
How to cite this article
Nnodim Johnkennedy and Opara Ambrose Uche, 2012. The Plasma Vitamin C and E Status in Type II Diabetes with Malaria in Owerri, Nigeria. Pakistan Journal of Nutrition, 11: 62-63.
REFERENCES
Baynes, J.W., 1991. Role of oxidative stress in development of complications in diabetes. Diabetes, 40: 405-412.
CrossRef PubMed Direct Link
Cheesbrough, M., 2000. District laboratory practice in tropical countries part 2. Cambrige University Press, Cambrige, pages: 464
Genet, S., R.K. Kale and N.Z. Baquer, 2002. Alterations in Antioxidatants enzymes and oxidative damage in experimental diabetic rat tissue. Effect of Vanadate and Fenugreek (Trigonlla Faenumgraeoum). Mol. Cell Biochem., 236: 7-12.
Dailey, G.E., M.A. Noor, J.S. Park, S. Bruce and F.T. Fiedorek, 2004. Glycemic control with glyburide/metformin tablets in combination with rosiglitazone in patients with type 2 diabetes: A randomized, double-blind trial. Am. J. Med., 116: 223-229.
PubMed
Halliwell, B. and J.M.C. Gutteridge, 2007. Free Radicals in Biology and Medicine. 4th Edn., Clarendon Press, Oxford, UK., ISBN-13: 9780198568698, Pages: 888
Kutlu, M., M. Nazioglu, H. Simsek, T. Yilmaz and A.H. Kukner, 2005. Moderate exercise combined with dietary vitamins C and E counteracts oxidative stress in the kidney and lens of streptozotocin-induced diabetic rat. Int. J. Vitamin Nutr. Res., 75: 71-80.
PubMed
Niki, E., 1991. Action of ascorbic acid as a scavenger of active and stable oxygen radicals. Am. J. Clin. Nutr., 54: 1119S-1124S.
CrossRef Direct Link
Nwanjo, H.U. and O.A. Ojiako, 2006. Effects of vitamin E and C on exercise induced oxidative stress. Global J. Med. Sci., 12: 199-2002.
Ojiako, O.A. and H.U. Nwanjo, 2007. plasma vitamin C and E levels inversely correlate with the risk of Ischaemic heart diseas in patients from Imo State, Nigeria. Biokemistri, 19: 29-34.
Direct Link
Singh, M., E. Dhanalakshini and M. Rao, 2000. Chemomodulatory action of Aloe vera on the profiles of enzymes associated with carcinogen metabolism and antioxidant status regulation in mice. Phytomedicine, 28: 317-324.
Tietz, W., 1976. Clinical Guide to Laboratory Tests. W.B. Saunders Co., Philadelphia, USA., Pages: 238
Tietz, W., 1976. Ascorbic acid. In: Fundamentals of Clinical Chemistry. Tietz, W. (Ed.). W.B. Saunders Company, Britain, pp: 422-419
Tirkey, N., S. Pilkhwal, A. Kuhad and K. Chopra, 2005. Hesperidn, a citrus bioflavonoid decreases the oxidative stress produced by carbon tetrachloride in rat liver and kidney. BMC Pharmacol., 10: 1471-2210.
Turner, R.C., C.A. Cull, V. Frighi, R.R. Holman and UK Prospective Diabetes Study Group, 1999. Glycemic control with diet, sulfonylurea, metformin, or insulin in patients with type 2 diabetes mellitus: Progressive requirement for multiple therapies (UKPDS 49). J. Am. Med. Assco., 281: 2005-2012.
CrossRef Direct Link
Uchimura, K., A. Nagasaka, R. Hayashi, M. Makino and M. Nagata et al., 1999. Changes in superoxide dismutase and myoloperoxidase activeties in leococutes from paients with diabetes mellitus. J. Diabet Complications, 13: 264-270.
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