Abstract: The objective of this survey was to know the influence of the biotope on the food regime of two species of catfishes of the basin of the Léfini river having an interest aquacade or economic. To arrive to this end, we captured and analyzed the stomachs of seventy six (76) specimens belonging to two species that are: Chrysichthys ornatus Boulenger 1902 (26 specimens) and Chrysichthys puntatus Boulenger 1899 (50 specimens). The two species have been captured in two different biotopes to know: the savanna and the forest. To appreciate the food régime according to these two biotopes, we calculated some parameters and food indications notably: the percentage of Occurrence (OC), the volumetric percentage (V) and the food indication (IA) of Lausanne. The done analyses show that the two studied species have a plastic food regime. This one varies according to the biotope. In savanna, the food regime of Chrysichthys ornatus has been varied more than in forest with a content stomacal where one identified eight (8) different preys against five (5) where dominate the scales cycloids with a percentage of occurrence of 75%. At Chrysichthys puntatus, on the other hand, the regime has been varied very in forest that in savanna with a content stomacal understanding five (5) types of preys against three (3) dominated by plant particles with a percentage of occurrence of 87%.