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Pakistan Journal of Biological Sciences

Year: 2005 | Volume: 8 | Issue: 6 | Page No.: 790-792
DOI: 10.3923/pjbs.2005.790.792
Effect of Decoction of Satureja khuzestanica Jamzad on Blood Coagulation Time, Triglyceride and Glucose Levels in Rats
A. Nazari, B. Delfan, Y. Shirkhani, A. A. Kiyanei and A. Mandegary

Abstract: The present study was designed to evaluate the effects of S. khuzestanica Jamzad decoction (SKJD) on blood coagulation in male rats. Effects of SKJD and S. khuzestanica Jamzad essential oil (SKJEO) on fasting blood glucose and triglyceride levels were evaluated as well. The SKJD significantly prolonged the Prothrombin Time (PT) and Activated Partial Thromboplastin Time (APTT) and decreased the blood concentration of glucose, but not triglyceride. The extract reduced the animal body weight as well. Meanwhile, SKJEO significantly reduced both glucose and triglyceride levels of blood.

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How to cite this article
A. Nazari, B. Delfan, Y. Shirkhani, A. A. Kiyanei and A. Mandegary, 2005. Effect of Decoction of Satureja khuzestanica Jamzad on Blood Coagulation Time, Triglyceride and Glucose Levels in Rats. Pakistan Journal of Biological Sciences, 8: 790-792.

Keywords: Satureja khuzestanica jamzad, medicinal plant, blood coagulation and hypoglycemic activity

REFERENCES
  • Zargari, A., 1990. Medicinal Plants. 4th Edn., Tehran University Publications, Iran, pp: 42

  • Abdollahi, M., A. Salehnia, S.H.R. Mortazavi, M. Ebrahimi and A. Shafiee et al., 2003. Antioxidant, antidiabetic, antihyperlipidemic, reproduction stimulatory properties and safety of essential oil of Satureja khuzestanica in rat in vivo: A toxicopharmacological study. Med. Sci. Monit., 9: 331-335.
    PubMed    

  • Abad, M.J., P. Bermejo, E. Gonzales, I. Iglesias, A. Irurzun and L. Carrasco, 1999. Antiviral activity of Bolivan plant extracts. Gen. Pharmacol., 32: 499-503.

  • Yamasaki, K., M. Nakano, T. Kawahata, H. Mori and T. Otake et al., 1998. Anti HIV-1 activity of herbs in Labiatae. Biol. Pharm. Bull., 21: 829-833.

  • Hajhashemi, V., A. Ghannadi and S.K. Pezeshkian, 2002. Antinociceptive and anti-inflammatory effects of Satureja hortensis L. extracts and essential oil. J. Ethnopharmacol., 82: 83-87.
    CrossRef    Direct Link    

  • Azaz, D., F. Demirci, F. Satil, M. Kurkcuoglu and K.H. Baser, 2002. Antimicrobial activity of some Satureja essential oils. Z. Naturforsch [C], 57: 817-821.
    Direct Link    

  • Panizzi, L., G. Flamini, P.L. Cioni and I. Morelli, 1993. Composition and antimicrobial properties of essential oils of four Mediterranean lamiaceae. J. Ethnopharmacol., 39: 167-170.

  • Rota, C., J.J. Carraminana, J. Burillo and A. Herrera, 2004. In vitro antimicrobial activity of essential oils from aromatic plants against selected foodborne pathogens. J. Food Prot., 67: 1252-1256.
    Direct Link    

  • Sokovic, M., O. Tzakou, D. Pitarokili and M. Couladis, 2002. Antifungal activities of selected aromatic plants growing wild in Greece. Nahrung, 46: 317-320.
    PubMed    

  • Hajhashemi, V., H. Sadrae, A.R. Ghannadi and M. Mohseni, 2000. Antispasmodic and anti-diarrhoeal effect of Satureja hortensis L. essential oil. J. Ethnopharmacol., 71: 187-192.

  • Radonic, A. and M. Milos, 2003. Chemical composition and in vitro evaluation of antioxidant effect of free volatile compounds from Satureja montana L. Free Radical Res., 37: 673-679.

  • Dorman, H.J.D., O. Bachmayer, M. Kosar and R. Hiltunen, 2004. Antioxidant properties of aqueous extracts from selected Lamiaceae species grown in Turkey. J. Agric. Food Chem., 52: 762-770.
    CrossRef    Direct Link    

  • Exarchou, V., N. Nenadis, M. Tsimidou, I.P. Gerothanassis, A. Troganis and D. Boskou, 2002. Antioxidant activities and phenolic composition of extracts from Greek oregano, Greek sage and summer savory. J. Agric. Food Chem., 50: 5294-5299.
    CrossRef    

  • Sanchez de Rojas, V.R., B. Somoza, T. Ortega and A.M. Villar, 1996. Isolation of vasodilatory active flavonoids from the traditional remedy Satureja obovata. Planta Med., 62: 272-274.
    PubMed    

  • Sefidkon, F. and S.H. Ahmadi, 2000. Essential oil of Satureja khuzestanica Jamzad. J. Essential Oil Res., 12: 127-128.

  • Quick, A.K., M. Stanley-Brown and F.W. Bancroft, 1935. A study of the coagulation defect in hemophilia and in jaundice. Am. J. Med. Sci., 180: 501-511.

  • Bell, W.N. and H.G. Alton, 1954. A brain extract as a substitute for platelet suspensions in the thromboplastin generation test. Nature, 174: 880-881.

  • Takahashi, Y., N. Inoba, S.H. Kuwahara and W. Kuki, 2003. Effects of gamma-terpinene on lipid concentrations in serum using Triton WR1339-treated rats. Biosci. Biotechnol. Biochem., 67: 2448-2450.

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