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Pakistan Journal of Biological Sciences

Year: 2005 | Volume: 8 | Issue: 7 | Page No.: 1001-1005
DOI: 10.3923/pjbs.2005.1001.1005
Comparison of Urinary o-Cresol and Hippuric Acid in Drivers, Gasoline Station Workers and Painters Exposed to Toluene in West of Iran
Abdulrahman Bahrami, Ahmad Jonidi-Jafari, Behzad Folladi, Hossien Mahjub, Qolamhosien Sadri and Majid Motamed Zadeh

Abstract: The aim of this study was evaluation of exposed to toluene and compare levels of hippuric acid and o-Cresol in taxi drivers, petrol station workers, car painters with a control group in West of Iran. The urinary o-creasol and toluene in air were analyzed by a gas chromatography and hippuric acid was extracted from urine and analyzed by high performance liquid chromatography. The significant differences in the levels of urinary o-Cresol were found in painters and petrol station workers compared to the control group (p<0.005). There was no significant correlation between toluene in air and biomarkers for taxi drivers. The lowest toluene concentration at which urinary hippuric acid increased to a measurable level was approximately 25 to 35 ppm and for o-Cresol was 2 ppm. In conclusion our results was showed that o-Cresol and hippuric acid could separate the exposed to toluene from the non-exposed when toluene in breathing zone of subjects was greater than 3 and 35 ppm, respectively. Hippuric acid and o-Cresol are not suitable biomarkers for occupations such as drivers that exposure to toluene in low concentration.

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How to cite this article
Abdulrahman Bahrami, Ahmad Jonidi-Jafari, Behzad Folladi, Hossien Mahjub, Qolamhosien Sadri and Majid Motamed Zadeh, 2005. Comparison of Urinary o-Cresol and Hippuric Acid in Drivers, Gasoline Station Workers and Painters Exposed to Toluene in West of Iran. Pakistan Journal of Biological Sciences, 8: 1001-1005.

Keywords: toluene, o cresol, Hipppuric acid and occupations

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