HOME JOURNALS CONTACT

Pakistan Journal of Biological Sciences

Year: 2004 | Volume: 7 | Issue: 10 | Page No.: 1730-1734
DOI: 10.3923/pjbs.2004.1730.1734
Biological Evaluation of Some Acylated Derivatives of D-mannose
Abul K.M.S. Kabir, Pijush Dutta and M. N. Anwar

Abstract: A number of D-mannose derivatives were evaluated for in vitro antibacterial activity against eleven human pathogenic bacteria. These compounds were also screened for in vitro antifungal activity against six plant pathogenic fungi. It was observed from the study that the tested acylated derivatives of D-mannose exhibited moderate to good antibacterial and antifungal activities. The acylated D-mannose derivatives were found to be more effective against fungal phytopathogens than those of the bacterial strains. For comparative study, the biological activity of two standard antibiotics (Ampicillin and Nystatin) were also measured. It was found that the antimicrobial functionality of D-mannose increased with the introduction of various acyl substituents and in some cases, this functionality was greater than or comparable to the antibiotics studied.

Fulltext PDF

How to cite this article
Abul K.M.S. Kabir, Pijush Dutta and M. N. Anwar, 2004. Biological Evaluation of Some Acylated Derivatives of D-mannose. Pakistan Journal of Biological Sciences, 7: 1730-1734.

Keywords: antibacterial activity and antifungal activity standard antibiotic food posoned technique

REFERENCES
  • Singh, H., K.N. Shukla, R. Dwivedi and L.D.S. Yadav, 1990. Clycloaddition of 4-amino-3-mercepto-1,2,4-triazole to heterocumulenes and antifungal activity of the resulting 1,2,4-triazolo[3,4-c]-1,2-dithia-4,5-diazines. J. Agric. Food. Chem., 38: 1483-1486.

  • Andary, C., R. Wylde, C. Laffite, G. Privat and F. Winternitz, 1982. Structures of verbascoside and orobanchoside, caffeic acid sugar esters from Orobanche rapum-genistae. Phytochemistry, 21: 1123-1127.
    CrossRef    Direct Link    

  • Gupta, R., S. Paul, A.K. Gupta, P.L. Kachroo and S. Bani, 1997. Synthesis and biological activities of some 2-substituted phenyl-3-(3-alkyl/aryl-5,6-dihydro-s-triazolo[3,4-b][1,3,4] thiazol-6-yl) indoles. Indian J. Chem., 36: 707-710.
    Direct Link    

  • Kabir, A.K.M.S., M.M. Matin, M.M.R. Bhuiyan and M.A. Rahim, 2001. Synthesis and characterization of some acylated derivatives of D-mannose. Chittagong Univ. J. Sci., 25: 65-73.

  • Kabir, A.K.M.S., M.M. Matin and A.F.M. Sanaullah, 2002. Regioselective synthesis and characterization of some lyxose derivatives. Ceylon J. Sci., 9: 9-14.

  • Kabir, A.K.M.S., M.M. Matin, M.J. Alam and M.A. Manchur, 2000. Synthesis and antimicrobial activities of some D-glucose derivatives. J. Bangladesh Chem. Soc., 13: 107-115.

  • Kabir, A.K.M.S., M.M. Matin, A.F.M. Sanaullah, M.A. Sattar and M.S. Rahman, 2001. Antimicrobial activities of some lyxoside derivatives. Bangladesh J. Microb., 18: 89-95.

  • Kabir, A.K.M.S., M.M. Matin, M. Ali and M.N. Anwar, 2003. Comparativestudies on selective acylation and antimicrobial activities of some D-glucofuranose derivatives. J. Bangladesh Aca. Sci., 27: 43-50.

  • Kabir, A.K.M.S, P. Dutta and M.N. Anwar, 2003. Synthesis of some D-mannose derivatives for antimicrobial screening studies. Chittagong Univ. J. Sci.

  • Bauer, A.W., W.M.M. Kirby, J.C. Sherris and M. Turck, 1966. Antibiotic susceptibility testing by a standardized single disk method. Am. J. Clin. Pathol., 45: 493-496.
    CrossRef    PubMed    Direct Link    

  • Grover, R.K. and J.D. Moore, 1962. Toximetric studies of fungicides against the brown rot organisms, Sclerotinia fructicola and S. laxa, Phytopathology, 52: 52-52.

  • Miah, M.A.T, H.U. Ahmed, N.R. Sharma, A. Ali and S.A. Miah, 1990. Antifungal activity of some plant extracts. Bangladesh J. Bot., 19: 5-10.

    • © Science Alert. All Rights Reserved