Abstract: Effect of growth hormones i.e., kinetin and gibberellic acid as well as heavy metal i.e., Pb(NO3)2 were studied pertaining to external and internal morphology of Cucumis sativus L. Moreover, the histomorphology of leaf was also studied. The following concentrations of growth hormones i.e., 40 ppm kinetin, 200 ppm GA3 and heavy metal i.e., 100 ppm Pb(NO3)2 and 200 ppm Pb(NO3)2 were applied individually. In combinations, they were 40 ppm kinetin, 100 ppm Pb(NO3)2, 40 ppm kinetin+200 ppm Pb(NO3)2, 200 ppm GA3+100 ppm Pb(NO3)2 and 200 ppm GA3+200 ppm Pb(NO3)2. In the external morphology, applied kinetin revealed reduction in the length of internode and petiole, which was accompanied by expansion in diameter. Furthermore, it increased the fresh and dry weight. Applied GA3 registered increase in length and inhibition in diameter and decrease in fresh and dry weight. Application of Pb(NO3)2 treatments showed decrease in length as well as in fresh and dry weight, which was accompanied by some expansion in diameter. The results of mixed doses of Pb(NO3)2 with kinetin and GA3 were more or less similar as observed in individual doses of kinetin and GA3. In the leaf, fresh and dry weight, leaf area and number of leaves were increased with kinetin. Contrarily Pb(NO3)2 treatments revealed inhibition in fresh and dry weight and leaf area. Moreover, number of stomata/mm2, stomatal index and %age of open stomata showed increase with kinetin. In the internal morphology of internode, the epidermis, cortical collenchyma and parenchyma, cambial region, xylary region and pith showed increase with kinetin and decrease with GA3. In the petiole, the epidermis, collenchymatous hypodermis and xylary elements showed expansion with kinetin and Pb(NO3)2 treatments, while inhibition was observed with GA3. In the case of leaf, width of epidermal cells, size and number of mesophyll cells and width of xylem elements revealed increase with kinetin, while rest of the treatments showed no significant effect.