Abstract: A water culture experiment was conducted to study salt tolerance of four cultivars of soybean (Glycine max L., cv. AGS-160, Loppa, Egyptian, ICAL-132) over a range of salinity (10-40 mM NaCl) at different stages of development. Salinity reduced growth, water balance and ion uptake mechanism of plant were affected adversely. The adverse effect of salinity became pronounced with passage of time and increase in salinity level. Water consumption, decreased with increase in salinity. This reduction was more in a tolerant (ICAL-132) than the sensitive (Loppa and AGS-160) cultivars. A quantitative relationship has been observed between ions and water uptake.