HOME JOURNALS CONTACT

Journal of Biological Sciences

Year: 2003 | Volume: 3 | Issue: 8 | Page No.: 681-684
DOI: 10.3923/jbs.2003.681.684
Safe Use of Salajeet During the Pregnancy of Female Mice
Ahmed R. Al-Himaidi and Mohammed Umar

Abstract: The effect of Salajeet on development of mice embryo was studied. A total of 71 pregnant female mice were given Salajeet (250 and 500 mg kg-1) orally via needle tube, daily from day 8-12 of pregnancy. All the treated and control animals showed no differences in the number of the litter size, the placenta and the body weight of the embryos and the number of resorped embryos at day 17 of gestation. However few abnormalities were observed in both treated and control groups.

Fulltext PDF

How to cite this article
Ahmed R. Al-Himaidi and Mohammed Umar , 2003. Safe Use of Salajeet During the Pregnancy of Female Mice. Journal of Biological Sciences, 3: 681-684.

Keywords: Salajeet, shilajit, pregnancy, embryo and development

REFERENCES
  • Al-Himaidi A. and M. Umar, 1999. In vitro fertilization of mouse ova obtained by three ways and their cleavage in commercially and chemically defined media. Saudi J. Biol. Soc., 6: 82-90.

  • Bhattacharya, S.K., A. Kumar and S. Ghosal, 1995. Effect of glycowithanlid from Withania somnifera on an animal model of Alzheimers disease and perturbed central cholinergic markers of cognition in rats. Phytother. Res., 9: 110-113.

  • Ghosal, S., J.P. Reddy and V.K. Lal, 1976. Shilajit. Part I. Chemical constituents. J. Pharma. Sci., 65: 772-773.

  • Ghosal, S., S.R. Singh, Y. Kumar, R.S. Srivastava, R.K. Goel, R. Day and S.K. Bhattacharya, 1988. Antiulcerogenic activity of fulvic acids and 4'-methoxy-6 carbomethoxybi phenyl isolated from shilajit. Phytother. Res., 2: 187-191.

  • Ghosal, S., J. Lal, S.K. Singh, G. Dasgupta, J. Bhaduri, S. Mukhopadhyay and S.K. Bhattacharya, 1989. Mast cell protecting effects of shilajit and its constituents. Phytother. Res., 3: 249-252.

  • Gupta, S.S., C.B. Seth and V.S. Mathur, 1966. Effect of gurmar and shilajit on body weight of young rats. Indian J. Physiol. Pharmacol., 9: 87-87.

  • Qureshi, S., M.M. Ahmed, S. Rafatullah, A.M. Al-Bekairi, M. Raza, F. Bibi and A.H. Shah, 1994. Effect of salajeet treatment on biochemical and cytological changes induced by cyclophosphamide in mice. Fitoterapia, 65: 137-140.

  • Schliebs, R., A. Liebmann, S.K. Bhattacharya, S. Ghosal and B. Volkerov, 1997. Systemi administration of defined extracts from Withania somnifer (Indian ginseng) and shilajit differential affects cholinergic but not glutamatergic and gabaergic markers in brain. Neuro. Chem. Int., 30: 181-190.

  • Aiken, G.R., D.M. McKnighty, R.L. Wershaw and P.M. Carthy, 1985. Humic Substances in Soil Sediments and Water. Wiley, UK., pp: 48-50

  • Bhattacharya, S.K., K.S. Satyan and A. Chakrabarti, 1997. Effect of Trasina, an Ayurvedic herbal formulation, on pancreatic islet superoxide dismutase activity in hyperglycaemic rats. Indian J. Exp. Biol., 35: 297-299.
    PubMed    

  • Chopra, R.N., K.L. Handa and L.D. Kapoor, 1958. Indigenous Drug of India. 2nd Edn., Dhar and Sons, Calcutta, India

  • Ghosal, S., S.K. Singh, R.S. Srivastava and Shilajit, 1988. Part II. biphenyl metabolites from Trifolium repens. J. Chem. Res., 196: 165-166.

  • Goel, R.K., R.J. Banergee and S.B. Acharya, 1999. Antiulcerogenic and anti-inflammatory studies with shilajit. J. E. Pharmacol., 29: 95-103.

    • © Science Alert. All Rights Reserved