Abstract: In vitro control of Alternaria solani was studied with different fungicides. Using Poison Food Technique (PFT), seven fungicides, Antracol, Benlate, Copper oxychloride, Dithane M-45, Ridomil, Topas, and Topsin were evaluated at four different concentrations (250, 500, 750, and 1000 ppm) to control colony growth of fungi . The lowest colony growth was recorded in Dithane M-45 treatment at 1000 ppm, and the highest in treatment where no fungicide was used, indicating the significance of using fungicides in controlling early blight disease in tomato