HOME JOURNALS CONTACT

Journal of Biological Sciences

Year: 2001 | Volume: 1 | Issue: 8 | Page No.: 761-764
DOI: 10.3923/jbs.2001.761.764
Plasma Free Amino Acids Levels in Rats with Parasitically Infected Liver
Nasreen Gill, M. Saleh Memon and M. Munif Khan

Abstract: Amino acid variation in different organs of rats Rettus norvegicus collected from different areas of Sindh for parasitic and biochemical analysis. Chromatographic separation of free amino acids, in normal and infected rats with endoparasites, using two different solvent system for avoiding overlapping have been used. The amino acid variation have been observed in liver (cyst) infection, liver (cyst) with intestine single (cestode) infection, liver (cyst) with intestine double (cestode +nematode) infection, liver (cyst) with blood single or both (sporozoan + trypanosome) infection, liver (cyst) with intestine (cestode) and blood (sporozoan or trypanosome) infection, liver (cyst) with intestine (nematode) infection. Isoleucine was totally absent in all types of infections. In liver (cyst) and blood (trypanosome and sporozoan) with double infection, only histidine was present in the plasma of the infected rats while all other amino acid which are normally present were totally absent. Leucine, methionine and valine were mostly absent except in some rats, infected with all type of endoparasitic infections.

Fulltext PDF

How to cite this article
Nasreen Gill, M. Saleh Memon and M. Munif Khan , 2001. Plasma Free Amino Acids Levels in Rats with Parasitically Infected Liver. Journal of Biological Sciences, 1: 761-764.

Keywords: Endoparasite, liver, plasma amino acid in rats, parasite, amino acids and parastics infections

REFERENCES
  • Fatima, T., 1991. Ecto and endoparasites of rat (Rattus rattus) of Multan and Khanewal (Punjab: Pakistan). M.Sc. Thesis, Institute of Applied Biology. Bahauddin Zakaria University, Multan, pp: 1-89.

  • Chappell, L.H., 1980. Physiology of Parasites. 1st Edn. Blackie and Son Ltd., Glasgow

  • Farooq, M. and S. Yousuf, 1986. A new trematodes from the intestine of Rattus rattus from campus, University of Karachi. Pak. J. Zool., 18: 341-343.

  • Lehninger, A., D. Nelson and M. Cox, 1993. Principles of Biochemistry. 2nd Edn., Worth Publishers, USA., Pages: 674

  • Stahl, E., 1969. Thin Layer Chromatography. 2nd Edn., Springer Verlag, Berlin, ISBN-13: 978-0387047362

  • Mohsin, M., M.M. Rahman, P.M. Das and A.K.M. Fazul-Haque, 1991. Haemotological observations in cattle naturally infected with Fasciola gigantica. Bangladesh Vet., 8: 31-34.

  • Ahmed, M., 1991. Essentials of Medical Biochemistry. 4th Edn., Merit Publishers, USA., pp: 272-302

  • Ahmed, Naseem, Jahangeer and Shakila, 1987. Free Amino Acids in Blood, Muscle, Liver, Kidney Heart and Brain of Varaus Bengalensis. University of Karachi, Karachi, pp: 63-69

  • Al-Bawari, S.E., J.K. Nasir and M. Zaia, 1987. Gastro-intestinal helminths of common rodents in Baghdad (Iraq) with record of Hymenolepios diminuta from hamaster. Science, 28: 299-308.

  • Zelmer, D., 1998. Life history and transmission dynamics of Halipegus occidualis (Digenea Hemiuridae). Ph.D. Thesis, Biology Department, Wake Forest University.

  • Bilqees, F.M. and I.H. Siddiqui, 1981. Two cestode from rats in Karachi. Pak. J. Agric. Res., 22: 68-70.

  • El-Naggar, H.M.S., 1994. Haematological changes in dogs infected with Ancylostoma duodenale. J. Egypt. Soc. Parasitol., 24: 69-75.

  • Faiyaz-ul-Haque, M.M. and P.R. Ahmed, 1990. Prevalence of helminth parasite in the digestive tract of house rat rattusrattus rufescenssin the twin cities of Rawalpindi-Islamabad. J. Sci., 14: 65-70.

  • Haq, M.M., M.J. Karim and H. Sheikh, 1985. Helminth parasites of house rats, mice and male in Bangladesh. Pak. Vet. J., 5: 143-144.

  • Jawadat, S.Z. and S.N. Mahmoud, 1980. The incidence of cestodan and Acanthocephalan parasites of some rodents in Iraq. Bull. Nat. Hist. Res., 7: 55-71.

  • Joshi, B.D., 1979. Biochemical changes in the liver and blood of a fresh water fish, Rita rita, infested with a trematode opisthorchis pedicellata. Folia Parasitologica, 26: 143-144.

  • Kameswari, M., G.R. Ramulu and L.N. Rao, 1975. Effect of helminth infections on the macromolecuar contents of the liver of the Rana tigrina. Indian J. Exp. Biol., 17: 976-979.

  • Khera, S. and P. Wadhawan, 1983. Quantitative and qualitative analysis of helminths fauna in Rattus rattus. Angew Zool., 70: 91-100.

  • Lim, B.L. and D. Heyneman, 1965. Host-parasites studies of angiostrongylus cantonensis (Nematode, Metastrongylidae) in Malaysian rodents: Natural infection of rodents and mulluscs in uraban and rural areas of central Malaya. Ann. Trop. Med. Parasitol., 59: 425-433.
    Direct Link    

  • Memon, M.A., 2001. Biochemical studies of urinary tract infection patients with special reference to amino acids variation in blood and urine. M.Phil Thesis, Institute of Biochemistry, University of Sindh, Jamshoro, Pakistan, pp: 203-207.

  • Mushtaq-ul-Hassan, M., M.A. Beg, A.A. Khan and M. Mahmood-ul-Hassan., 1997. Some population attributes of the house rats, Rattus rattus, of rural central Punjab, Pakistan. Pak. J. Zool., 29: 199-202.

  • Romaniuk, K., M. Michalski, R. Sokol and M. Szelagiewicz, 1993. Influence of Eimeria spp. and round worms on the level of some haematological and biochemical indices in the blood of lambs. Medycyna Waterynary, 49: 273-275.

  • Taylar, B.S., L.H. Alarcon and T.R. Billiar, 1999. Inducible Nitri Oxide Synthase in Liver: Regulation and Function. University of Pittsburgh, USA., pp: 1-26

  • Tenora, F., E. Murai and F. Meszaros, 1973. Quantative and qualitative analysis of helminth fauna of Microtus arvalis (Rodentia, Microtidae) in Europe. Parasitol. Hung., 6: 131-147.

    • © Science Alert. All Rights Reserved