Efficacy of HVT-IBDV Vector Vaccine Against Recent Egyptian vvIBDV in Commercial
Broiler Chickens
Abstract:
The efficacy of a turkey herpesvirus (HVT-IBD) vector vaccine
encoding the VP2 gene of Infectious Bursal Disease (IBD) was evaluated in comparison
with classic vaccines on two commercial broiler chicken farms (A and B), with
high levels of Maternal Derived Antibodies (MDA). The HVT-IBD vaccine was administrated
into chickens of farm A at 1-day-old while intermediate and intermediate-plus
vaccines were given at 1-and 14-day-old into chickens of farm B, respectively.
An early significant seroconversion was detected at 21-day-old in chickens of
farm A, while no significant serological response was detected in farm B at
this time. The antibody level was significantly higher in chickens in farm A
at 28-and 35-day-old. Moreover, HVT-IBD vaccine provided complete protection
against recent Egyptian vvIBDV isolate. In conclusion, HVT-IBD vaccine has the
ability to induce an immune response in birds with high levels of MDA and could
protect against recent Egyptian vvIBDV isolates.
How to cite this article
Hesham Sultan, Hussein A. Hussein, Alaa G. Abd El-Razik, Sallah El-Balall, Shaima M. Talaat and Awad A. Shehata, 2012. Efficacy of HVT-IBDV Vector Vaccine Against Recent Egyptian vvIBDV in Commercial
Broiler Chickens. International Journal of Poultry Science, 11: 710-717.
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