HOME JOURNALS CONTACT

International Journal of Poultry Science

Year: 2012 | Volume: 11 | Issue: 6 | Page No.: 397-399
DOI: 10.3923/ijps.2012.397.399
Ultrastructural Studies of Involuting Bursa and Thymus of Giriraja Birds (Gallus domesticus)
Leena Chandrasekhar, R.V. Prasad and K.V. Jamuna

Abstract: The ultra structural changes of involuting cells of bursa of fabricius and thymus could be classified as nuclear and cytoplasmic changes. Major cytoplasmic changes include arrangement of cytoskeletal filaments in parallel arrays, cytoplasmic membrane blebbing and dilatation of endoplasmic reticulum. Nuclear changes included clumping of chromatin, elongation and appearance of convolutions of the nuclear membrane with karyorrhexis, karyolysis and nucleolar disintegration. There is consequent cell volume reduction, detachment of cell from surroundings, formation of several membrane bound apoptotic bodies and its ingestion by neighboring cells.

Fulltext PDF

How to cite this article
Leena Chandrasekhar, R.V. Prasad and K.V. Jamuna, 2012. Ultrastructural Studies of Involuting Bursa and Thymus of Giriraja Birds (Gallus domesticus). International Journal of Poultry Science, 11: 397-399.

Keywords: Ultrastructure, involution, bursa and thymus

REFERENCES
  • Luft, J.H., 1961. Improvements in epoxy resin embedding methods. J. Biophys. Biochem. Cytol., 9: 409-414.
    Direct Link    

  • Machaca, K. and M.M. Compton, 1993. Analysis of thymic lymphocyte apoptosis using in vitro techniques. Dev. Comparative Immunol., 17: 263-276.
    CrossRef    

  • Negoescu, A., P. Lorimier, F. Labat-Moleur , L. Azoti and C. Robert et al., 1997. TUNEL: Improvement and evaluation of the method for In situ apoptotic cell identification. Biochemica, 2: 12-17.
    Direct Link    

  • West, N.J., E.D. Courtney, A.P. Poullis and R.J. Leicester, 2009. Apoptosis in the colonic crypt, colorectal adenomata and manipulation by chemoprevention. Cancer Epidemiol. Biomarkers Prev., 18: 1680-1687.
    PubMed    

  • MacLellan, W.R. and M.D. Scheider, 1997. Death by design: Programmed cell death in cardiovascular biology and disease. Circ. Res., 81: 137-144.
    CrossRef    Direct Link    

  • Sanchez-Refusta, F., E. Ciriaco, A. Germana, G. Germana and J.A. Vega, 1996. Age-related changes in the medullary reticular epithelial cells of the pigeon bursa of Fabricius. Anat. Rec., 246: 473-480.
    PubMed    

  • Tizard, I.R., 2000. Veterinary Immunology: And Introduction. 6th Edn., W.B. Saunders Company, Philadelphia, ISBN: 9780721682181, pp: 161-162

  • O'Donnell McGee, J., P.G. Isaacson and N.A. Wright, 1992. Oxford Textbook of Pathology. Oxford University Press, Oxford, UK., ISBN: 9780192619754, Pages: 2344

    • © Science Alert. All Rights Reserved