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Research Article
 

Efficacy of Extracts of African Eggplant and Okra Leaves on Alloxan-Induced Diabetes Mellitus Adult Male Albino Rats



Ethel E.O. Onuora and Christiana N. Okafor
 
ABSTRACT

Diabetes mellitus is one of the major disease that is common among many communities in Nigeria. Among the two types of diabetes mellitus (Types 1 and 2), type 2 is the most common. There is tendency for its increase due to genetic, environmental factors such as obesity, increasing number of elderly people and lack of exercise. Drugs for treatment of diseases are expensive for the low income groups in Nigeria. Plants have medicinal, food and economic values. Herbal medicine is the mainstay for about 75 to 80% of the low income groups to treat diabetes mellitus. This is due to better cultural acceptability and compatibility with the human body and minimum side-effects. This study evaluated the efficacy of extracts of African eggplant (Solanum macrocarpon L.) and okra (Abelmoschus esculentus L.) leaves on alloxan induced diabetic adult male albino rats. The extracts were able to tremendously lower the high blood glucose levels of the diabetic rats to normal. The rats fed with 300 mg level of leaf extract of A. esculentus had the highest decrease when compared with others. The total cholesterol, high and low density cholesterol and triglycerides values of the rats were also lowered by the two extracts.

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  How to cite this article:

Ethel E.O. Onuora and Christiana N. Okafor, 2016. Efficacy of Extracts of African Eggplant and Okra Leaves on Alloxan-Induced Diabetes Mellitus Adult Male Albino Rats. Pakistan Journal of Nutrition, 15: 551-555.

DOI: 10.3923/pjn.2016.551.555

URL: https://scialert.net/abstract/?doi=pjn.2016.551.555

REFERENCES
Amin, I.M., 2011. Nutritional properties of Abelmoschus esculentus as remedy to manage diabetes mellitus: A literature review. Proceedings of the International Conference on Biomedical Engineering and Technology, Volume 11, June 4-5, 2011, IPCBEE IACSIT Press, Singapore, pp: 44-57.

Anwar, F., U. Rashid, M. Ashraf and M. Nadeem, 2010. Okra (Hibiscus esculentus) seed oil for biodiesel production. Applied Energy, 87: 779-785.
Direct Link  |  

Bansal, P., 2002. Healing Powers of Foods. Pustak Mahsal, India.

Burkill, H.M., 1985. The Useful Plants of West Tropical Africa. 2nd Edn., Vol. 2, Royal Botanic Gardens, Kew, London, Pages: 960.

Chinedu, S.N., A.C. Olasumbo, O.K. Eboji, O.C. Emiloju, O.K. Arinola and D.I. Dania, 2011. Proximate and phytochemical analyses of Solanum aethiopicum L. and Solanum macrocarpon L. fruits. Res. J. Chem. Sci., 1: 63-71.
Direct Link  |  

Collins, E.M., 2010. An A-Z Guide to Healing Foods: A Shopper's Reference. Vol. 2, Florida Institute of Horticulture, Conari Press, Florida, USA., pp: 23-45.

Denton, O.A., 2004. Justicia ladanoides Lam. In: Record from PROTA4U, Grubben, G.J.H. and O.A. Denton (Eds.). Plant Resources of Tropical Africa, Wageningen, Netherlands, pp: 335-345.

Gbile, Z.O., 1987. Nigerian Solanum species. Nig. Field., 52: 19-26.

Gunn-Moore, D.A., T.D. Watson, S.J. Dodkin, A.C. Blaxter, S.M. Crispin and T.J. Gruffydd-Jones, 1997. Transient hyperlipidaemia and anaemia in kittens. Vet. Record, 140: 355-359.
CrossRef  |  Direct Link  |  

Harbone, J.B., 1984. Phytochemical Methods: A Guide to Modern Technique of Plant Analysis. Chapman and Hall, London, pp: 60-64.

IDF., 2007. Diabetes Atlas. 3rd Ed., International Diabetes Federation, USA., pp: 46-48.

Kwon, Y.I., E. Apostolidis and K. Shetty, 2008. In vitro studies of eggplant (Solanum melongena) phenolics as inhibitors of key enzymes relevant for type 2 diabetes and hypertension. Bioresour. Technol., 99: 2981-2988.
CrossRef  |  Direct Link  |  

Lung'aho, M.G. and R.P. Glahn, 2009. In vitro estimates of iron bioavailability in some Kenyan complementary foods. Food Nutr. Bull., 30: 145-152.
CrossRef  |  Direct Link  |  

Martin, F.W., 1982. Okra, potential multiple-purpose crop for the temperate zones and tropics. Econ. Bot., 36: 340-345.
CrossRef  |  Direct Link  |  

Mays, D.A., W. Buchanan, B.N. Bradford and P.M. Giordano, 1990. Fuel Production Potential of Several Agricultural Crops. In: Advances in New Crops, Janick, J. and J.E. Simon (Eds.). Timber Press, Portland, OR., pp: 260-263.

Mbanya, J.C.N., A.A. Motala, E. Sobngwi, F.K. Assah and S.T. Enoru, 2010. Diabetes in sub-Saharan Africa. Lancet, 375: 2254-2266.
CrossRef  |  Direct Link  |  

Oboh, G., M.M. Ekperigin and M.I. Kazeem, 2005. Nutritional and haemolytic properties of eggplants (Solanum macrocarpon) leaves. J. Food Compos. Anal., 18: 153-160.
CrossRef  |  Direct Link  |  

Ramachandran, A., C. Snehalatha and V. Viswanathan, 2002. Burden of type 2 diabetes and its complications-the Indian scenario. Curr. Sci., 83: 1471-1476.
Direct Link  |  

Sabitha, V., S. Ramachandran, K.R. Naveen and K. Panneerselvam, 2011. Antidiabetic and antihyperlipidemic potential of Abelmoschus esculentus (L.) Moench. in streptozotocin-induced diabetic rats. J. Pharm. BioAllied Sci., 3: 397-402.
CrossRef  |  Direct Link  |  

Saxena, A.M., M.B. Bajpai and S.K. Mukherjee, 1991. Swerchirin induced blood sugar lowering of streptozotocin treated hyperglycemic rats. Indian J. Exp. Biol., 29: 674-675.
PubMed  |  

Siemonsma, J.S. and C. Kouame, 2004. Abelmoschus esculentus (L.) Monech. In: PROTA 2: Vegetables/Legumes, Grubben, G.J.H. and O.A. Denton (Eds.). PROTA, Wageningen, The Netherlnds.

Sodipo, O.A., F.I. Abdulrahman, U.K. Sandabe and J.A. Akinniyi, 2009. Effect of Solanum macrocarpum Linn. on biochemical liver function in diet-induced hypercholesterolaemic rats. Nig. Vet. J., 30: 1-8.

Waugh, A. and A. Grant, 2006. Ross and Wilson Anatomy and Physiology in Health and Illness. 10th Edn., Churchill Livingstone, Elsevier Ltd., Spain, ISBN 0443101019, pp: 490.

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