Subscribe Now Subscribe Today
Research Article
 

Nutritional and Phytochemical Composition of Moringa oleifera Lam and its Potential Use as Nutraceutical Plant: A Review



A. Godinez-Oviedo, N. Guemes-Vera and O.A. Acevedo-Sandoval
 
Facebook Twitter Digg Reddit Linkedin StumbleUpon E-mail
ABSTRACT

Moringa oleifera Lam. is a plant that is known for its nutritional value and particularly for its protein quantity and quality. Due to its nutrient constitution, M. oleifera is used in several regions to treat malnutrition, especially in children. Moreover, M. oleifera contains phytochemical compounds that have important biological activities. Several previous studies confirmed that extracts or compounds isolated from M. oleifera have antioxidant, anti-carcinogenic, anti-diabetic, anti-inflammatory and anti-hypertensive properties, as well as the ability to protect against hepatic damage. This review discusses the characteristics and potential benefits of M. oleifera nutrients and phytochemicals.

Services
Related Articles in ASCI
Similar Articles in this Journal
Search in Google Scholar
View Citation
Report Citation

 
  How to cite this article:

A. Godinez-Oviedo, N. Guemes-Vera and O.A. Acevedo-Sandoval, 2016. Nutritional and Phytochemical Composition of Moringa oleifera Lam and its Potential Use as Nutraceutical Plant: A Review. Pakistan Journal of Nutrition, 15: 397-405.

DOI: 10.3923/pjn.2016.397.405

URL: https://scialert.net/abstract/?doi=pjn.2016.397.405

REFERENCES
1:  Abdulkarim, S.M., K. Long, O.M. Lai, S.K.S. Muhammad and H.M. Ghazali, 2005. Some physico-chemical properties of moringa oleifera seed oil extracted using solvent and aqueous enzymatic methods. Food Chem., 93: 253-263.
CrossRef  |  Direct Link  |  

2:  Abdulkarim, S.M., K. Long, O.M. Lai, S.K.S. Muhammad and H.M. Ghazali, 2007. Frying quality and stability of high-oleic Moringa oleifera seed oil in comparison with other vegetable oils. Food Chem., 105: 1382-1389.
CrossRef  |  Direct Link  |  

3:  Adedapo, A.A., O.M. Mogbojuri and B.O. Emikpe, 2009. Safety evaluations of the aqueous extract of the leaves of Moringa oleifera in rats. J. Med. Plants Res., 3: 586-591.
Direct Link  |  

4:  Akinlolu, A.A., O.K. Ghazali, O.M. Ameen, S.C. Oyebanji, G.O. Omotoso and B.U. Enaibe, 2014. Moringa oleifera impairs the morphology and functions of the kidney in adult wistar rats. Int. J. Morphol., 32: 469-474.
CrossRef  |  Direct Link  |  

5:  Alhakmani, F., S. Kumar and S.A. Khan, 2013. Estimation of total phenolic content, in-vitro antioxidant and anti-inflammatory activity of flowers of Moringa oleifera. Asian Pac. J. Trop. Biomed., 3: 623-627.
CrossRef  |  Direct Link  |  

6:  Al‐Said, M.S., R.A. Mothana, M.A. Al‐Yahya, A.S. Al‐Blowi, M. Al‐Sohaibani, A.F. Ahmed and S. Rafatullah, 2012. Edible oils for liver protection: Hepatoprotective potentiality of Moringa oleifera seed oil against chemical‐induced hepatitis in rats. J. Food Sci., 77: T124-T130.
CrossRef  |  Direct Link  |  

7:  Anjorin, T.S., P. Ikokoh and S. Okolo, 2010. Mineral composition of Moringa oleifera leaves, pods and seeds from two regions in Abuja, Nigeria. Int. J. Agric. Biol., 12: 431-434.
Direct Link  |  

8:  Anwar, F. and M.I. Bhanger, 2003. Analytical characterization of Moringa oleifera seed oil grown in temperate regions of Pakistan. J. Agric. Food Chem., 51: 6558-6563.
CrossRef  |  PubMed  |  Direct Link  |  

9:  Anwar, F., M. Ashraf and M.I. Bhanger, 2005. Interprovenance variation in the composition of Moringa oleifera oilseeds from Pakistan. J. Am. Oil Chem. Soc., 82: 45-51.
CrossRef  |  Direct Link  |  

10:  Anwar, F., S. Latif, M. Ashraf and A.H. Gilani, 2007. Moringa oleifera: A food plant with multiple medicinal uses. Phytother. Res., 21: 17-25.
CrossRef  |  PubMed  |  Direct Link  |  

11:  Ashfaq, M., S.M.A. Basra and U. Ashfaq, 2012. Moringa: A miracle plant for agro-forestry. J. Agric. Soc. Sci., 8: 115-122.
Direct Link  |  

12:  Aslam, M., F. Anwar, R. Nadeem, U. Rashid, T.G. Kazi and M. Nadeem, 2005. Mineral composition of Moringa oleifera leaves and pods from different regions of Punjab, Pakistan. Asian J. Plant Sci., 4: 417-421.
CrossRef  |  Direct Link  |  

13:  Atawodi, S.E., J.C. Atawodi, G.A. Idakwo, B. Pfundstein and R. Haubner et al., 2010. Evaluation of the polyphenol content and antioxidant properties of methanol extracts of the leaves, stem and root barks of Moringa oleifera Lam. J. Med. Food, 13: 710-716.
CrossRef  |  Direct Link  |  

14:  Banerji, R., S.C. Verma and P. Pushpendra, 2003. Oil potential of Moringa. Nat. Prod. Radiance, 2: 68-69.
Direct Link  |  

15:  Bennett, R.N., F.A. Mellon, N. Foidl, J.H. Pratt, M.S. Dupont, L. Perkibns and P.A. Kroon, 2003. Profiling glucosinolates and phenolics in vegetative and reproductive tissues of the multi-purpose trees Moringa oleifera L. (Horseradish Tree) and Moringa stenopetala L. J. Agric. Food Chem., 51: 3546-3553.
CrossRef  |  PubMed  |  Direct Link  |  

16:  Berkovich, L., G. Earon, I. Ron, A. Rimmon, A. Vexler and S. Lev-Ari, 2013. Moringa Oleifera aqueous leaf extract down-regulates nuclear factor-kappaB and increases cytotoxic effect of chemotherapy in pancreatic cancer cells. BMC Complement. Altern. Med., Vol. 13. 10.1186/1472-6882-13-212

17:  Bharali, R., J. Tabassum and M.R. Azad, 2003. Chemomodulatory effect of Moringa oleifera, Lam, on hepatic carcinogen metabolising enzymes, antioxidant parameters and skin papillomagenesis in mice. Asian Pac. J. Cancer Prev., 4: 131-139.
PubMed  |  Direct Link  |  

18:  Teixeira, E.M.B., M.R.B. Carvalho, V.A. Neves, M.A. Silva and L. Arantes-Pereira, 2014. Chemical characteristics and fractionation of proteins from Moringa oleifera Lam. leaves. Food Chem., 147: 51-54.
CrossRef  |  Direct Link  |  

19:  Cheenpracha, S., E.J. Park, W.Y. Yoshida, C. Barit, M. Wall, J.M. Pezzuto and L.C. Chang, 2010. Potential anti-inflammatory phenolic glycosides from the medicinal plant Moringa oleifera fruits. Bioorg. Med. Chem., 18: 6598-6602.
CrossRef  |  Direct Link  |  

20:  Chumark, P., P. Khunawat, Y. Sanvarinda, S. Phornchirasilp and N.P. Morales et al., 2008. The in vitro and ex vivo antioxidant properties, hypolipidaemic and antiatherosclerotic activities of water extract of Moringa oleifera Lam. leaves. J. Ethnopharmacol., 116: 439-446.
CrossRef  |  PubMed  |  Direct Link  |  

21:  Costa-Lotufo, L.V., M.T.H. Khan, A. Ather, D.V. Wilke and P.C. Jimenez et al., 2005. Studies of the anticancer potential of plants used in Bangladeshi folk medicine. J. Ethnopharmacol., 99: 21-30.
CrossRef  |  PubMed  |  Direct Link  |  

22:  Das, N., K. Sikder, S. Ghosh, B. Fromenty and S. Dey, 2012. Moringa oleifera Lam. leaf extract prevents early liver injury and restores antioxidant status in mice fed with high-fat diet. Indian J. Exp. Biol., 50: 404-412.
PubMed  |  Direct Link  |  

23:  Dhakar, R.C., S.D. Maurya, B.K. Pooniya, N. Bairwa and M. Gupta, 2011. Moringa: The herbal gold to combat malnutrition. Chron. Young Sci., 2: 119-125.
CrossRef  |  Direct Link  |  

24:  Fahey, J.W., 2005. Moringa oleifera: A review of the medical evidence for its nutritional, therapeutic and prophylactic properties. Part 1. Trees Life J., Vol. 1. 10.1201/9781420039078.ch12

25:  Faizi, S., B.S. Siddiqui, R. Saleem, K. Aftab, F. Shaheen and A.H. Gilani, 1998. Hypotensive constituents from the pods of Moringa oleifera. Planta Med., 64: 225-228.
CrossRef  |  PubMed  |  Direct Link  |  

26:  Faizi, S., B.S. Siddiqui, R. Saleem, S. Siddiqui and K. Aftab et al., 1994. Isolation and structure elucidation of new nitrile and mustard oil glycosides from moringa oleifera and their effect on blood pressure. J. Nat. Prod., 57: 1256-1261.
CrossRef  |  PubMed  |  Direct Link  |  

27:  Faizi, S., B.S. Siddiqui, R. Saleem, S. Siddiqui, K. Aftab and A.H. Gilani, 1995. Fully acetylated carbamate and hypotensive thiocarbamate glycosides from Moringa oleifera. Phytochemistry, 38: 957-963.
CrossRef  |  PubMed  |  Direct Link  |  

28:  Fakurazi, S., I. Hairuszah and U. Nanthini, 2008. Moringa oleifera lam prevents acetaminophen induced liver injury through restoration of glutathione level. Food Chem. Toxicol., 46: 2611-2615.
CrossRef  |  Direct Link  |  

29:  Fakurazi, S., U. Nanthini and H. Ithnin, 2008. Hepatoprotective and antioxidant action of Moringa oleifera Lam. againsts acetaminophen induced hepatoxicity in rats. Int. J. Pharm., 4: 270-275.
Direct Link  |  

30:  Ferreira, P.M.P., D.F. Farias, J.T. de Abreu Oliveira and A.D.F.U. Carvalho, 2008. Moringa oleifera: Bioactive compounds and nutritional potential. Rev. Nutr., 21: 431-437.
Direct Link  |  

31:  Ghasi, S., E. Nwobodo and J.O. Ofili, 2000. Hypocholesterolemic effects of crude extract of leaf of Moringa oleifera Lam in high-fat diet fed wistar rats. J. Ethnopharmacol., 69: 21-25.
CrossRef  |  PubMed  |  Direct Link  |  

32:  Guevara, A.P., C. Vargas, H. Sakurai, Y. Fujiwara and K. Hashimoto et al., 1999. An antitumor promoter from Moringa oleifera Lam. Mutat. Res./Genet. Toxicol. Environ. Mutagen., 440: 181-188.
CrossRef  |  Direct Link  |  

33:  Gupta, R., M. Mathur, V.K. Bajaj, P. Katariya, S. Yadav, R. Kamal and R.S. Gupta, 2012. Evaluation of antidiabetic and antioxidant activity of Moringa oleifera in experimental diabetes. J. Diabetes, 4: 164-171.
CrossRef  |  Direct Link  |  

34:  Hamza, A.A., 2010. Ameliorative effects of Moringa oleifera Lam seed extract on liver fibrosis in rats. Food Chem. Toxicol., 48: 345-355.
CrossRef  |  PubMed  |  Direct Link  |  

35:  Hukkeri, V.I., C.V. Nagathan, R.V. Karadi and B.S. Patil, 2006. Antipyretic and wound healing activities of Moringa oleifera Lam. in rats. Indian J. Pharm. Sci., 68: 124-126.
CrossRef  |  Direct Link  |  

36:  Iqbal, S. and M.I. Bhanger, 2006. Effect of season and production location on antioxidant activity of Moringa oleifera leaves grown in Pakistan. J. Food Comp. Anal., 19: 544-551.
CrossRef  |  Direct Link  |  

37:  Jain, P.G., S.D. Patil, N.G. Haswani, M.V. Girase and S.J. Surana, 2010. Hypolipidemic activity of Moringa oleifera Lam., Moringaceae, on high fat diet induced hyperlipidemia in albino rats. Revista Brasileira de Farmacognosia, 20: 969-973.
CrossRef  |  Direct Link  |  

38:  Jaiswal, D., P.K. Rai, A. Kumar, S. Mehta and G. Watal, 2009. Effect of Moringa oleifera Lam. leaves aqueous extract therapy on hyperglycemic rats. J. Ethnopharmacol., 123: 392-396.
CrossRef  |  PubMed  |  Direct Link  |  

39:  Jaiswal, D., P.K. Rai, S. Mehta, S. Chatterji and S. Shukla et al., 2013. Role of Moringa oleifera in regulation of diabetes-induced oxidative stress. Asian Pacific J. Trop. Med., 6: 426-432.
CrossRef  |  Direct Link  |  

40:  Jung, I.L., 2014. Soluble extract from Moringa oleifera leaves with a new anticancer activity. PloS ONE, Vol. 9. 10.1371/journal.pone.0095492

41:  Karadi, R.V., N.B. Gadge, K.R. Alagawadi and R.V. Savadi, 2006. Effect of Moringa oleifera Lam. root-wood on ethylene glycol induced urolithiasis in rats. J. Ethnopharmacol., 105: 306-311.
CrossRef  |  PubMed  |  Direct Link  |  

42:  Kashiwada, Y., F.A. Ahmed, S.I. Kurimoto, S.Y. Kim, H. Shibata, T. Fujioka and Y. Takaishi, 2012. New α-glucosides of caffeoyl quinic acid from the leaves of Moringa oleifera Lam. J. Nat. Med., 66: 217-221.
CrossRef  |  Direct Link  |  

43:  Kasolo, J.N., G.S. Bimenya, L. Ojok, J. Ochieng and J.W. Ogwal-Okeng, 2010. Phytochemicals and uses of Moringa oleifera leaves in Ugandan rural communities. J. Med. Plants Res., 4: 753-757.
Direct Link  |  

44:  Kumar, N.A. and L. Pari, 2003. Antioxidant action of Moringa oleifera Lam. (Drumstick) against antitubercular drugs induced lipid peroxidation in rats. J. Med. Food, 6: 255-259.
CrossRef  |  PubMed  |  Direct Link  |  

45:  Kumari, D.J., 2010. Hypoglycaemic effect of Moringa oleifera and Azadirachta indica in type 2 diabetes mellitus. Bioscan, 5: 211-214.
Direct Link  |  

46:  Kumbhare, M.R., V. Guleha and T. Sivakumar, 2012. Estimation of total phenolic content, cytotoxicity and in-vitro antioxidant activity of stem bark of Moringa oleifera. Asian Pac. J. Trop. Dis., 2: 144-150.
CrossRef  |  Direct Link  |  

47:  Lalas, S. and J. Tsaknis, 2002. Characterization of Moringa oleifera seed oil variety Periyakulam 1. J. Food Compos. Anal., 15: 65-77.
CrossRef  |  Direct Link  |  

48:  Lalas, S. and J. Tsaknis, 2002. Extraction and identification of natural antioxidant from the seeds of the Moringa oleifera tree variety of Malawi. J. Am. Oil Chem. Soc., 79: 677-683.
CrossRef  |  Direct Link  |  

49:  Mahajan, S.G., R.G. Mali and A.A. Mehta, 2007. Protective effect of ethanolic extract of seeds of Moringa oleifera Lam. against inflammation associated with development of arthritis in rats. J. Immunotoxicol., 4: 39-47.
CrossRef  |  Direct Link  |  

50:  Makkar, H.P.S. and K. Becker, 1996. Nutrional value and antinutritional components of whole and ethanol extracted Moringa oleifera leaves. Anim. Feed Sci. Technol., 63: 211-228.
CrossRef  |  Direct Link  |  

51:  Mehta, A. and B. Agrawal, 2008. Investigation into the mechanism of action of Moringa oleifera for its anti-asthmatic activity. Orient. Pharm. Exp. Med., 8: 24-31.
Direct Link  |  

52:  Mehta, L.K., R. Balaraman, A.H. Amin, P.A. Bafna and O.D. Gulati, 2003. Effect of fruits of Moringa oleifera on the lipid profile of normal and hypercholesterolaemic rabbits. J. Ethnopharmacol., 86: 191-195.
CrossRef  |  PubMed  |  Direct Link  |  

53:  Mensah, J.K., B. Ikhajiagbe, N.E. Edema and J. Emokhor, 2012. Phytochemical, nutritional and antibacterial properties of dried leaf powder of Moringa oleifera (Lam) from Edo Central province, Nigeria. J. Nat. Plant Resour., 2: 107-112.
Direct Link  |  

54:  Morton, J.F., 1991. The horseradish tree, Moringa pterygosperma (Moringaceae): A boon to arid lands? Econ. Bot., 45: 318-333.
CrossRef  |  Direct Link  |  

55:  Moyo, B., P.J. Masika, A. Hugo and V. Muchenje, 2011. Nutritional characterization of Moringa (Moringa oleifera Lam.) leaves. Afr. J. Biotechnol., 10: 12925-12933.
Direct Link  |  

56:  Muangnoi, C., P. Chingsuwanrote, P. Praengamthanachoti, S. Svasti and S. Tuntipopipat, 2012. Moringa oleifera pod inhibits inflammatory mediator production by lipopolysaccharide-stimulated RAW 264.7 murine macrophage cell lines. Inflammation, 35: 445-455.
CrossRef  |  Direct Link  |  

57:  Ndong, M., M. Uehara, S.I. Katsumata and K. Suzuki, 2007. Effects of oral administration of Moringa oleifera Lam on glucose tolerance in Goto-Kakizaki and Wistar rats. J. Clin. Biochem. Nutr., 40: 229-233.
CrossRef  |  Direct Link  |  

58:  Nikkon, F., Z.A. Saud, M.H. Rahman and M.E. Haque, 2003. In vitro antimicrobial activity of the compound isolated from chloroform extract of Moringa oleifera Lam. Pak. J. Biol. Sci., 6: 1888-1890.
CrossRef  |  Direct Link  |  

59:  Oduro, I., W.O. Ellis and D. Owusu, 2008. Nutritional potential of two leafy vegetables: Moringa oleifera and Ipomoea batatas leaves. Sci. Res. Essay, 3: 57-60.
Direct Link  |  

60:  Ogbunugafor, H.A., F.U. Eneh, A.N. Ozumba, M.N. Igwo-Ezikpe and J. Okpuzor et al., 2011. Physico-chemical and antioxidant properties of Moringa oleifera seed oil. Pak. J. Nutr., 10: 409-414.
CrossRef  |  Direct Link  |  

61:  Oliveira, J.T.A., S.B. Silveira, I.M. Vasconcelos, B.S. Cavada and R.A. Moreira, 1999. Compositional and nutritional attributes of seeds from the multiple purpose tree Moringa oleifera Lamarck. J. Sci. Food Agric., 79: 815-820.
CrossRef  |  Direct Link  |  

62:  Manguro, L.O.A. and P. Lemmen, 2007. Phenolics of Moringa oleifera leaves. Nat. Prod. Res., 21: 56-68.
CrossRef  |  Direct Link  |  

63:  Pari, L. and N.A. Kumar, 2002. Hepatoprotective activity of Moringa oleifera on antitubercular drug-induced liver damage in rats. J. Med. Food, 5: 171-177.
CrossRef  |  Direct Link  |  

64:  Pari, L. and N.A. Kumar, 2002. Hepatoprotective activity of Moringa oleifera on antitubercular drug-induced liver damage in rats. J. Med. Food, 5: 171-177.
CrossRef  |  Direct Link  |  

65:  Ramachandran, C., K.V. Peter and P.K. Gopalakrishnan, 1980. Drumstick (Moringa oleifera): A multipurpose Indian vegetable. Econ. Bot., 34: 276-283.
CrossRef  |  Direct Link  |  

66:  Rashid, U., F. Anwar, B.R. Moser and G. Knothe, 2008. Moringa oleifera oil: A possible source of biodiesel. Bioresour. Technol., 99: 8175-8179.
CrossRef  |  PubMed  |  Direct Link  |  

67:  Richter, N., P. Siddhuraju and K. Becker, 2003. Evaluation of nutritional quality of moringa (Moringa oleifera Lam.) leaves as an alternative protein source for Nile tilapia (Oreochromis niloticus L.). Aquaculture, 217: 599-611.
CrossRef  |  Direct Link  |  

68:  Sashidhara, K.V., J.N. Rosaiah, E. Tyagi, R. Shukla, R. Raghubir and S.M. Rajendran, 2009. Rare dipeptide and urea derivatives from roots of Moringa oleifera as potential anti-inflammatory and antinociceptive agents. Eur. J. Med. Chem., 44: 432-436.
CrossRef  |  Direct Link  |  

69:  Siddhuraju, P. and K. Becker, 2003. Antioxidant properties of various solvent extracts of total phenolic constituents from three different agroclimatic origins of drumstick tree (Moringa oleifera Lam.) leaves. J. Agric. Food Chem., 51: 2144-2155.
CrossRef  |  PubMed  |  Direct Link  |  

70:  Singh, B.N., B.R. Singh, R.L. Singh, D. Prakash, R. Dhakarey, G. Upadhyay and H.B. Singh, 2009. Oxidative DNA damage protective activity, antioxidant and anti-quorum sensing potentials of Moringa oleifera. Food Chem. Toxicol., 47: 1109-1116.
CrossRef  |  Direct Link  |  

71:  Singh, R.S.G., P.S. Negi and C. Radha, 2013. Phenolic composition, antioxidant and antimicrobial activities of free and bound phenolic extracts of Moringa oleifera seed flour. J. Funct. Foods, 5: 1883-1891.
CrossRef  |  Direct Link  |  

72:  Sreelatha, S. and P.R. Padma, 2009. Antioxidant activity and total phenolic content of Moringa oleifera leaves in two stages of maturity. Plant Foods Hum. Ntur., 64: 303-311.
CrossRef  |  PubMed  |  Direct Link  |  

73:  Sreelatha, S. and P.R. Padma, 2010. Protective mechanisms of Moringa oleifera against CCl4-induced oxidative stress in precision-cut liver slices. Forschende Komplementarmedizin, 17: 189-194.
CrossRef  |  Direct Link  |  

74:  Sreelatha, S., A. Jeyachitra and P.R. Padma, 2011. Antiproliferation and induction of apoptosis by Moringa oleifera leaf extract on human cancer cells. Food Chem. Toxicol., 49: 1270-1275.
CrossRef  |  Direct Link  |  

75:  Tree for Life, 2005. Moringa book. http://www.treesforlife.org/our-work/our-initiatives/moringa/moringa-book.

76:  Verma, A.R., M. Vijayakumar, C.S. Mathela and C.V. Rao, 2009. In vitro and in vivo antioxidant properties of different fractions of Moringa oleifera leaves. Food Chem. Toxicol., 47: 2196-2201.
CrossRef  |  PubMed  |  Direct Link  |  

77:  Vongsak, B., P. Sithisarn, S. Mangmool, S. Thongpraditchote, Y. Wongkrajang and W. Gritsanapan, 2013. Maximizing total phenolics, total flavonoids contents and antioxidant activity of Moringa oleifera leaf extract by the appropriate extraction method. Ind. Crop Prod., 44: 566-571.
CrossRef  |  Direct Link  |  

78:  Zvinorova, P.I., L. Lekhanya, K. Erlwanger and E. Chivandi, 2015. Dietary effects of Moringa oleifera leaf powder on growth, gastrointestinal morphometry and blood and liver metabolites in Sprague Dawley rats. J. Anim. Physiol. Anim. Nutr., 99: 21-28.
CrossRef  |  Direct Link  |  

©  2020 Science Alert. All Rights Reserved