ABSTRACT
The present study was designed to analyze the effect of water intake rat offsprings body length and IGF-1 hormone level of rats An experimental animal study using randomized block design was applied to pregnant female of rats with gestation age ±22 days. Body length and IGF-1 hormone level of the offspring were measured at the age of five weeks after born. The results showed the mean offsprings body length at birth was 44.22±1.99, 46.20±3.93, 50.69±3.14, 52.17±2.48, 52.05±2.67 and 52.48±2.27 mm for water intake level of 1, 3, 6, 9, 12 and 15 ml, respectively. The result of ANOVA test showed that water intake level significantly and positively affects body length with coeficient of determination of 76.33%; but not significant for IGF-1 hormone level. This implies that chronic dehydration during pregnancy of rat affects offsprings linear growth.
PDF References Citation
How to cite this article
Afrinia Eka Sari, Hardinsyah and Ikeu Tanziha, 2015. Effect of Water Intake on Sprague-Dawley Rat Off Springs Linear Growth. Pakistan Journal of Nutrition, 14: 436-439.
DOI: 10.3923/pjn.2015.436.439
URL: https://scialert.net/abstract/?doi=pjn.2015.436.439
DOI: 10.3923/pjn.2015.436.439
URL: https://scialert.net/abstract/?doi=pjn.2015.436.439
REFERENCES
- Aboderin, F.I. and V.O. Oyetayo, 2006. Haematological studies of rats fed different doses of probiotic, Lactobacillus plantarum, isolated from fermenting corn slurry. Pak. J. Nutr., 5: 102-105.
CrossRefDirect Link - Burn, J.F., E. Varlet-Marie, P. Connes and I. Aloulou, 2010. Hemorheological alterations related to training and overtraining. Biorheology, 47: 91-115.
CrossRefPubMedDirect Link - Coyle, E.F., 1998. Cardiovascular drift during prolonged exercise and the effects of dehydration. Int. J. Sports Med., 19: S121-S124.
CrossRefPubMedDirect Link - Lao, T.T., K.F. Tam and L.Y. Chan, 2000. Third trimester iron status and pregnancy outcome in non-anaemic women; pregnancy unfavourably affected by maternal iron excess. Hum. Reprod., 15: 1843-1848.
CrossRefDirect Link - Allen, L.H., 2000. Anemia and iron deficiency: Effects on pregnancy outcome. Am. J. Clin. Nutr., 71: 1280S-1284S.
Direct Link - Underwood, M.A., W.M. Gilbert and M.P. Sherman, 2005. Amniotic fluid: Not just fetal urine anymore. J. Perinatol., 25: 341-348.
CrossRefDirect Link - Blankson, M.L., R.L. Goldenberg, G. Cutter and S.P. Cliver, 1993. The relationship between maternal hematocrit and pregnancy outcome: Black-white differences. J. Natl. Med. Assoc., 85: 130-134.
PubMed - Khoigani, M.G., S. Goli and A. Hasanzadeh, 2012. The relationship of hemoglobin and hematocrit in the first and second half of pregnancy with pregnancy outcome. Iran. J. Nursing Midwifery Res., 17: S165-S170.
PubMed - Gluckman, P.D. and C.S. Pinal, 2003. Regulation of fetal growth by the somatotrophic axis. J. Nutr., 133: 1741S-1746S.
Direct Link - Peyreigne, C., D. Bouix, C. Fedou and J. Mercier, 2001. Effect of hydration on exercise-induced growth hormone response. Eur. J. Endocrinol., 145: 445-450.
CrossRefDirect Link - Popkin, B.M., K.E. D'Anci and I.H. Rosenberg, 2010. Water, hydration and health. Nutr. Rev., 68: 439-458.
CrossRefDirect Link - Shirreffs, S.M., 2003. Markers of hydration status. Eur. J. Clin. Nutr., 57: S6-S9.
CrossRefDirect Link - Shumway, J.B., A. Al-Malt, E. Amon, B. Cohlan, S. Amini, M. Abboud and M.H. Winn, 1999. Impact of oligohydramnios on maternal and perinatal outcomes of spontaneous premature rupture of the membranes at 18-28 weeks. J. Maternal-Fetal Med., 8: 20-23.
CrossRefDirect Link - Tong, X.L., L. Wang, T.B. Gao, Y.G. Qin, Y.Q. Qi and Y.P. Xu, 2009. Potential function of amniotic fluid in fetal development-novel insights by comparing the composition of human amniotic fluid with umbilical cord and maternal serum at mid and late gestation. J. Chin. Med. Assoc., 72: 368-373.
CrossRefDirect Link