A.M. Areej
Department of Animal Resource, Department of Basic Science, College of Agriculture, University of Baghdad, Baghdad, Iraq
Sanaa A. Al-Hammed
Department of Animal Resource, College of Agriculture, University of Baghdad, Baghdad, Iraq
A.M. Rawaa
Department of Basic Science, College of Agriculture, University of Baghdad, Baghdad, Iraq
ABSTRACT
An oily injectable administration of [Di nitrate- bis {p-methyl anilino phenyl aceto nitrite} cadmium (II)] -2H2O and its molecular formula [Cd (HL)1(NO3)2] - 2H2O and tested against E. coli (sensitivity test) in vitro showed inhibitory zone of 12 mm. The CLC was injected subcutaneously in the layer chickens neck (Lohman brown) at different levels, T1 0.0%, T2 0.25%, T3 0.50% and T4 1.0%. After five days E. coli was orally administrated by drinking water at concentration of 8500 x 106 cells/ml (highly pathogenic) as causative agent of Salpengitis and Ovaritis. The results after four months were revealed that the treated chickens showed a resistance against E. coli infection; moreover, all the blood parameters are within the normal ranges. The protective effects of CLC in respect to blood biochemical's activities which are then confirmed by measuring the residual concentration of Cd in liver and egg of treated chickens by using the graphite furnace atomic absorption. The results showed that, the liver and eggs are free from any residues. The hematological results of this study are associated with the normal control (T1), while there are significant increases in blood parameters of (T4) in Hb, PCV, RBCs, WBCs, Glucose, Total protein, Total albumin, Total globulins and High Density Lipoprotein (HDL), but there was significant decrease in Low Density Lipoprotein (LDL).The obtained results refer to the safety use of CLC as a synthetic chemical prophylactic agent against E. coli during the production period of layers, in addition to its inexpensive cost.
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How to cite this article
A.M. Areej, Sanaa A. Al-Hammed and A.M. Rawaa, 2012. The Injection Effect of Local Oily Cadmium Ligand Compound on the Blood Performances of Layer Chickens. Pakistan Journal of Nutrition, 11: 635-638.
DOI: 10.3923/pjn.2012.635.638
URL: https://scialert.net/abstract/?doi=pjn.2012.635.638
DOI: 10.3923/pjn.2012.635.638
URL: https://scialert.net/abstract/?doi=pjn.2012.635.638
REFERENCES
- Crouse, J.R., J.S. Parks, H.M. Schey and F.R. Kahl, 1985. Studies of low density lipoprotein molecular weight in human beings with coronary artery disease. J. Lipid Res., 26: 566-574.
PubMedDirect Link - Deaton, J.W., F.N. Reece and W.J. Tarver, 1969. Hematocrit, hemoglobin and plasma-protein levels of broilers reared under constant temperatures. Poult. Sci., 48: 1993-1996.
CrossRef - Heafele, C., C. Bonfils and Y. Sauvaire, 1997. Characterization of adioxygenase from Trigonella foenum-graecum involved in 4-hydroxyisoleucine biosynthesis. Phytochemistry, 44: 563-566.
Direct Link - Jeyaprakash, K. and P. Chinnaswamy, 2005. Effect of Spirulina and Liv-52 on cadmium induced toxicity in albino rats. Indian J. Exp. Biol., 43: 773-781.
PubMedDirect Link - Khosla, P., D.D. Gupta and R.K. Nagpal, 1995. Effect of Trigonella foenum graecum (Fenugreek) on blood glucose in normal and diabetic rats. Indian. J. Physiol. Pharmacol., 39: 173-174.
PubMedDirect Link - Perrier, V., A.C. Wallace, K. Kaneko, J. Safa, S.B. Prusiner and F.E. Cohen, 2000. Mmcking dominant negative inhibition of prion replication through structure-based drug design. Proc. Nat. Acad. Sci. USA., 23: 6073-6078.
Direct Link - Pirarat, N., P. Chotipong and P. Singhasenee, 2008. Toxicity of cadmium on tilapia (Oreochromis niloticus) spleen. Proceedings of the 15th Congress of FAVA-OIE Joint Symposium on Emerging Diseases, October 27-30, 2008, Bangkok, Thailand, pp: 143-144.
Direct Link - Prasanna, M., 2000. Hypolipidemic effect of fenugreek: A clinical study. Indian J. Pharmacol., 32: 34-36.
Direct Link - Sarkar, S., P. Yadav, R. Trivedi, A.K. Bansal and D. Bhatnagar, 1995. Cadmium-induced lipid peroxidation and the status of the antioxidant system in rat tissues. J. Trace Elem. Med. Biol., 9: 144-149.
CrossRefDirect Link - Postel, D., A.N. van Nhien, M. Pillon, P. Villa and G. Ronco, 2000. Stereoselective synthesis of α-aminonitriles at non-anomeric positions of monosaccharides. Tetrahydron Lett., 41: 6403-6406.
CrossRef - Warnick, G.R. and P.D. Wood, 1995. National cholesterol education program recommendations for measurement of high-density lipoprotein cholesterol: Executive summary. Clin. Chem., 41: 1427-1433.
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