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Research Article

Effect of “Folere” Juice (Calyx of Hibiscus sabdariffa Lin) on Some Biochemical Parameters in Humans

Maffo Tazoho Ghislain, Etame Loe Gisele, Pankoui Mfonkeu Joel Bertrand, Feukeng Mathieu, Fotso Kuate Honore, Tchouanguep Mbiapo Felicite and Gouado Inocent
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This study aimed to evaluate the effect of the consumption of “Folere” juice extracted from the dried calyx of Hibiscus sabdariffa Lin on some biochemical parameters in humans. A standardized extraction procedure of the juice was set up using a survey carried out on 10 “foleré” juice sellers in Douala town. An enrolment of 22 apparently healthy male volunteers was done and these were observed before and throughout the study period. Each subject consumed 1 liter of juice per day (half in the morning and half in the evening). Glucose, haemoglobin, serum iron, total cholesterol, triglycerides, High density lipoprotein cholesterol, low density lipoprotein cholesterol, aspartate aminotransferase, alanine aminotransferase and C-reactive protein levels were all determined at days 0, 4 and 9. Results shows that “Folere” juice significantly decreases the serum level of serum iron, total cholesterol and high density lipoprotein (p<0.05) and increases significantly triglycerides and haemoglobin levels (p<0.05). Also, no differences in blood glucose levels were obtained during the study period. Furthermore, a non significant decrease in transaminases levels was also observed. These findings suggest that “folere” juice can safely be used in the prevention and management of anaemia and cardiovascular diseases and may also have some level of hepatoprotective effects as far as transaminases are concerned.

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Maffo Tazoho Ghislain, Etame Loe Gisele, Pankoui Mfonkeu Joel Bertrand, Feukeng Mathieu, Fotso Kuate Honore, Tchouanguep Mbiapo Felicite and Gouado Inocent, 2011. Effect of “Folere” Juice (Calyx of Hibiscus sabdariffa Lin) on Some Biochemical Parameters in Humans. Pakistan Journal of Nutrition, 10: 755-759.

DOI: 10.3923/pjn.2011.755.759


1:  Carvajal-Zarrabal,O.,S.M. Waliszewski, D.M. Barradas-Dermitz, Z. Orta-Flores and P.M. Hayward-Jones et al., 2005. The consumption of Hibiscus sabdariffa dried calyx ethanolic extract reduced lipid profile in rats. Plant Foods Hum. Nutr., 60: 153-159.
CrossRef  |  

2:  Chen, C.C., F.P. Chou, Y.C. Ho, W.L. Lin and C.P. Wang et al., 2004. Inhibitory effects of Hibiscus sabdariffa L extract on low-density lipoprotein oxidation and anti-hyperlipidemia in fructose-fed and cholesterol-fed rats. J. Sci. Food Agric., 84: 1989-1996.
CrossRef  |  Direct Link  |  

3:  Friedewald, W.T., R.I. Levy and D.S. Fredrickson, 1972. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin. Chem., 18: 499-502.
CrossRef  |  PubMed  |  Direct Link  |  

4:  Gupta, S. and J. Prakash, 2009. Studies on Indian green leafy vegetables for their antioxidant activity. Plant Foods Hum. Nutr., 64: 39-45.
CrossRef  |  Direct Link  |  

5:  Hercberg, S. and P. Galan, 1991. Apports Conseilles en Mineraux (Fer): Apports Nutritionnels Conseilles Pour la Population Francaise. 2nd Edn., Lavoisier, Paris, pp: 39-41.

6:  Hunter, K.J. and J.M. Fletcher, 2002. The antioxidant activity and composition of fresh, frozen, jarred and canned vegetable. Innovation Food Sci. Emerg. Technol., 3: 399-406.
CrossRef  |  Direct Link  |  

7:  Kariola, A.C. and G.V.Z. Dedoussis, 2007. Natural antioxidant compounds in risk factors of cardiovascular diseases. Pharm. Res., 103: 4-18.

8:  Kaur, C. and H.C. Kapoor, 2005. Antioxidant activity of some fruits in Indian diet. Acta Horticulturae, 696: 563-565.
CrossRef  |  Direct Link  |  

9:  McMahon, B.J., S.R. Albert, R.B. Wainwright and A.P. Lanier, 1990. Hepatitis B released squelae: Prospective study in 1400 hepatitis surface antigens-positive alaska carriers, Arch. Int. Med., 150: 1051-1054.
PubMed  |  

10:  Morton, L.W., C.R. Abu-Amsha, I.B. Puddey and K.D. Croft, 2000. Chemistry and biological effects of dietary phenolic compounds: Relevance to cardiovascular diseases. Clin. Exp. Pharmacol. Physiol., 27: 152-159.
PubMed  |  

11:  Ologundudu, A., A.O. Ologundudu, I.A. Ololade and F.O. Obi, 2009. Effect of Hibiscus sabdariffa anthocyanins on 2,4-dinitrophenylhydrazine-induced hematotoxicity in rabbits. Afr. J. Biochem. Res., 3: 140-144.
Direct Link  |  

12:  Olsen, A., J. Nawiri and H. Friis, 2000. The impact of iron supplementation on reinfection with intestinal helminths and schistosoma mansoni in western Kenya. Trans. R. Soc. Trop. Med. Hyg., 94: 493-499.
PubMed  |  

13:  Promphorn, P., P. Laddawal, C. Chaiyo, N. Nuansri and L. Somsong, 2006. Aqueous extract of calyces of Hibiscus sabdariffa Lin: Effects on hepatic cytochrome P450 and subacute toxicity in rats. Thai J. Pharm. Biol., 30: 8-18.
Direct Link  |  

14:  Sue, R., 1994. Essentials Minerals of Nutrition and Diet Therapy. 6th Edn., Mosby Publisher, USA., pp: 49-409.

15:  Lin, T.L., H.H. Lin, C.C. Chen, M.C. Lin, M.C. Chou and C.J. Wang, 2007. Hibiscus sabdariffa extract reduces serum cholesterol in men and women. Nutr. Res., 27: 140-145.
CrossRef  |  Direct Link  |  

16:  Visioli, F., L. Borsani and C. Galli, 2000. Diet and prevention of coronary heart disease: The potential role of phytochemicals. Cardiovasc. Res., 47: 419-425.
CrossRef  |  

17:  Hirunpanich, V., A. Utaipat, N.P. Morales, N. Bunyapraphatsara, H. Sato, A. Herunsale and C. Suthisisang, 2006. Hypocholesterolemic and antioxidant effects of aqueous extracts from the dried calyx of Hibiscus sabdariffa L. in hypercholesterolemic rats. J. Ethnopharmacol., 103: 252-260.
CrossRef  |  

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