Submit Manuscript

Pakistan Journal of Nutrition

Year: 2011 | Volume: 10 | Issue: 3 | Page No.: 238-240
Facebook Twitter Digg Reddit Linkedin StumbleUpon E-mail

ABSTRACT

Infertility is one of the most tragic of all marital problems. Despite recent advances in the treatment of male infertility, the problem has not been satisfactorily tackled. The infertility may be due to an inadequate number of spermatozoa in the semen, the failure of the spermatozoa to move with sufficient vigor towards their goal or that they are deficient in other respects. Aims of the study is to investigate the safety and efficacy of Xperm (Herbal Medicine) in test group in comparison with Sulfonylureas plus (Allopathic) in control group. A Causi experimental randomized controlled, two-arm parallel group clinical trial conducted at Shifa-ul-Mulk Memorial Hospital for Eastern Medicine, Hamdard University Karachi. Hundred patients in the age group of 20-50 years with idiopathic infertility with a total sperm count less than 20 million/ml. Comparison of data recorded by participants relating to these variables showed significant differences between test and control groups (p<0.05) despite the fact that no side effects were at all recorded in test group. Overall clinical success was observed in both treatment groups however the efficacy of the test treated medication (Xperm) was superior as p = 0.03. Xperm is more effective than the Sulfonylureas plus in the treatment of Oligospermia and male infertility.
PDF References Citation

Search

REFERENCES

  1. Brown, G.A., M.D. Vukovich, E.R. Martini, M.L. Kohut, W.D. Franke, D.A. Jackson and D.S. King, 2001. Endocrine and lipid responses to chronic androstenediol herbal supplementation in 30 to 58 year old men. J. Am. Coll. Nutr., 20: 520-528.
    Direct Link
  2. Brown, G.A., M.D. Vukovich, T.A. Reifenrath, N.L. Uhl, K.A. Parsons, R.L. Sharp and D.S. King, 2000. Effects of anabolic precursors on serum testosterone concentrations and adaptations to resistance training in young men. Int. J. Sport Nutr. Exercise Metab., 10: 340-359.
    PubMed
  3. Brugh, V.M. and L.I. Lipshultz, 2004. Male factor infertility: Evaluation and management. Med. Clin. North Am., 88: 367-385.
    PubMed
  4. Bucci, L.R., 2000. Selected herbals and human exercise performance. Am. J. Clin. Nutr., 72: 624S-636S.
    PubMedDirect Link
  5. Cooper, T.G., E. Noonan, S. von Eckardstein, J. Auger and H.W.G. Baker et al., 2010. World Health Organization reference values for human semen characteristics. Hum. Reprod. Update, 16: 231-245.
    Direct Link
  6. Greenberg, S.H., L.I. Lipshultz and A.J. Wein, 1978. Experience with 425 subfertile male patients. J. Urol., 119: 507-510.
    PubMed
  7. Guzick, D.S., J.W. Overstreet, P. Factor-Litvak, C.K. Brazil and S.T. Nakajima et al., 2001. National cooperative reproductive medicine network. Sperm morphology, motility and concentration in fertile and infertile men. N. Engl. J. Med., 345: 1388-1393.
  8. Hirsh, A., 2003. Male subfertility. BMJ, 327: 669-672.
  9. MacLeod, J., 1951. Semen quality in 1000 men of known fertility and in 800 cases of infertile marriage. Fertil Steril, 2: 115-139.
  10. Makar, R.S. and T.L. Toth, 2002. The evaluation of infertility. Pathol. Patterns Rev., 117: S95-S103.
    CrossRefDirect Link
  11. Sallmen, M., C.R. Weinberg, D.D. Baird, M.L. Lindbohm and A.J. Wilcox, 2005. Has human fertility declined over time: Why we may never know. Epidemiol., 16: 494-499.
  12. World Health Organization, 1987. Towards more objectivity in diagnosis and management of male fertility. Int. J. Androl., 7: 1-35.

Search

Comments

kwesi Reply

i wish to say that i was not very happy to know that i was oligospermia patient i have tried to cure myself to no avail my current sperm count is 4m,i want you to help me to increase my count in order for me to father a child.thanks a lot.

Leave a Comment

Your email address will not be published. Required fields are marked *