Amr A. Rezq
Department of Nutrition and Food Science, Faculty of Home Economics, Helwan University, Cairo, Egypt
Fatma A. Labib
Department of Nutrition and Food Science, Faculty of Home Economics, Helwan University, Cairo, Egypt
Abd Elrahman M. Attia
Department of Nutrition and Food Science, Faculty of Home Economics, Helwan University, Cairo, Egypt
ABSTRACT
Amount and type of fats in the diet have an important effect on bone health and lipid profile. This study was conducted to investigate the effect of different types of dietary oils and fats on lipid profile, calcium absorption and bone mineralization in male mice. Mice weighing 25±5 g were divided into nine groups and fed on diets without oils or fats (control group) and containing soybean oil, corn oil, olive oil, palm oil, sunflower oil, butter, animal fat or margarine. Mice fed on diet containing soybean oil or olive oil had the lowest levels of TG, TC, LDL-c and HDL-c as compared to the other groups. Diets with palm oil, olive oil, sunflower oil, butter, animal fat or margarine caused significant decreases in the serum level of calcium as compared to the effect of diet without oils or fats. Mice fed diet containing olive oil, butter or animal fat had significant increase in bone density, while those fed diet containing soybean oil, corn oil, sunflower oil or margarine had significant decreases in femur bone density, compared to the control group. The apparent calcium absorption was significantly increased by feeding diets containing soybean oil, corn oil, palm oil, olive oil, sunflower oil, butter or animal fat. Dietary intake of vegetable oils improved lipid profile while butter, animal fat and margarine had the opposite effect. Butter and animal fats increased calcium and phosphorus deposition in femur bone more than vegetable oils.
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How to cite this article
Amr A. Rezq, Fatma A. Labib and Abd Elrahman M. Attia, 2010. Effect of Some Dietary Oils and Fats on Serum Lipid Profile, Calcium Absorption and Bone Mineralization in Mice. Pakistan Journal of Nutrition, 9: 643-650.
DOI: 10.3923/pjn.2010.643.650
URL: https://scialert.net/abstract/?doi=pjn.2010.643.650
DOI: 10.3923/pjn.2010.643.650
URL: https://scialert.net/abstract/?doi=pjn.2010.643.650
REFERENCES
- Annemieke, M.B., A.M. Melanie, G.J. Engels, E.P. Boerma and M.P. Sabine, 1997. Changes in bone mineral density, body composition and lipid metabolism during Growth Hormone (GH) treatment in children with GH deficiency. J. Clin. Endocrinol. Metabol., 82: 2423-2428.
Direct Link - Asadi, F., A. Shahriari, M. Pourkabir and R. Maclaren, 2008. Short and long-term effects of corn oil on serum lipid and lipoprotein and visceral abdominal in rats. J. Food Lipi., 15: 68-80.
CrossRefDirect Link - Brownbill, R.A., M. Petrosian and J.Z. Ilich, 2005. Association between dietary conjugated linoleic acid and bone mineral density in postmenopausal women. J. Am. Coll. Nutr., 24: 177-181.
Direct Link - Haag, M., O.N. Magada, N. Claassen, L.H. Bohmer and M.C. Kruger, 2003. Omega-3 fatty acids modulate ATPases involved in duodenal calcium absorption. Prostaglandins Leukot Essent Fatty Acids., 68: 423-429.
PubMed - Hayes, K.C., A. Pronezuk, S. Lindsey and D. Diersen-Schade, 1991. Dietary saturated fatty acids (12:0, 14:0, 16:0) differ in their impact on plasma cholesterol and lipoproteins in nonhuman primates. Am. J. Clin. Nutr., 53: 491-498.
Direct Link - Hoffman, R., L. Lawrence, D. Kronfeld, W. Cooper, D. Sklan and J. Dascanio, 1999. Dietary carbohydrates, and fat influence radiographic bone mineral content in growing foals. J. Anim. Sci., 77: 3330-3338.
Direct Link - Jie, M.Z., S. Shimanuki, A. Igarashi, Y. Kawasaki and M. Yamaguchi, 2000. Preventive effect of dietary soybean on bone Loss in ovariectomized rats: Enhancement with isoflavone and zinc supplementation. J. Health Sci., 46: 263-268.
Direct Link - Karaji-Bani, M., F. Montazeri and M. Hashemi, 2006. Effect of palm oil on serum lipid profile in rats. Pak. J. Nutr., 5: 234-236.
CrossRefDirect Link - Kris-Etheton, P.M. and S. Yu, 1997. Individual fatty acid, effect on plasma lipids and lipoproteins: Human studies. Am. J. Clin. Nutr., 65: 1628S-1644S.
Direct Link - Lee, K.N., D. Kritchevsky and M.W. Pariza, 1994. Conjugated linoleic acid and atherosclerosis in rabbits. Atherosclerosis, 108: 19-25.
CrossRefPubMedDirect Link - Lichtenstein, A.H., L.M. Ausman, W. Carrasco, J.L. Jenner, J.M. Ordovas and E.J. Schaefer, 1993. Hydrogenation impairs the hypolipidemic effect of corn oil in humans. Hydrogenation, trans fatty acids and plasma lipids. Arterioscler Thromb, 13: 154-161.
PubMed - Liu, D., H.P. Veit, J.H. Wilson and D.M. Denbow, 2003. Long-term supplementation of various dietary lipids alter bone mineral content, mechanical properties and histological characteristics of Japanese quail. Poult. Sci., 82: 831-839.
PubMed - Mensink, R.P. and M.B. Katan, 1990. Effect of dietary tram fatty acids on high-density and low-density lipoprotein cholesterol levels in healthy subjects. N. Engl. J. Med., 323: 439-445.
PubMed - Mollard, R.C. and H.A. Weiler, 2006. Dietary arachidonic acid and docosahexaenoic acid elevate femur calcium and reduce zinc content in piglets. Pediatr. Res., 60: 418-422.
PubMed - Oluba, O.M., O. Adeyemi, G.C. Ojieh, C.O. Aboluwoye and G.O. Eidangbe, 2008. Comparative effect of soybean oil and palm oil on serum lipids and some serum enzymes in cholesterol-fed rats. Eur. J. Sci. Res., 23: 559-566.
Direct Link - Parhami, F., 2003. Possible role of oxidized lipids in osteoporosis: Could hyperlipidemia be a risk factor: Prostaglandins Leukot Essent. Fatty Acids, 68: 373-378.
PubMed - Puela, C., A. Quintina, A. Agaliasa, J. Matheya, C. Obleda and A. Mazura, 2004. Olive oil and its main phenolic micronutrient (oleuropein) prevent inflammation-induced bone loss in the ovariectomised rat. Br. J. Nutr., 92: 119-127.
PubMed - Reeves, P.G., F.H. Nielsen and G.C. Fahey Jr., 1993. AIN-93 purified diets for laboratory rodents: Final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet. J. Nutr., 123: 1939-1951.
CrossRefPubMedDirect Link - Scholtz, S.C., M. Pieters, W. Oosthuizen, J.C. Jerling, M.J. Bosman and H.H. Vorster, 2004. The effect of red palm olein and refined palm olein on lipids and haemostatic factors in hyperfibrinogenaemic subjects. Throm. Res., 113: 13-25.
PubMed - Shad, M.A., A.T. Iqbal and M. Tayyabe, 2002. Serum lipid profile: The effects of dietary pufa and mufa an experimental animal study. Prof. Med. J., 9: 116-120.
Direct Link - Snedecor, G.R. and R.G. Cochran, 1980. Statistical Methods. 7th Edn., Iwoa State University Press, Ames, Iowa, ISBN: 9780813815602, Pages: 507.
Direct Link - Wardlaw, G.M. and J.T. Snook, 1990. Effect of diets high in butter, corn oil, or high-oleic acid sunflower oil on serum lipids and apolipoproteins in men. Am. J. Clin. Nutr., 51: 815-821.
PubMed - Watkins, B.A., C.L. Shen, K.G. Allen and M.F. Seifert, 1996. Dietary (n-3) and (n-6) polyunsaturates and acetylsalicylic acid alter ex vivo PGE2 biosynthesis, tissue IGF-I levels and bone morphometry in chicks. J. Bone. Miner. Res., 11: 1321-1332.
PubMed - Watkins, B.A., C.L. Shen, J.P. McMurtry, H. Xu, S.D. Bain and K.G. Allen, 1997. Dietary lipids modulate bone prostaglandin E2 production, insulin-like growth factor-1 concentrations and formation rate in chicks. J. Nutr., 127: 1084-1091.
Direct Link - Watkins, B.A. and M.F. Seifert, 2000. Conjugated linoleic acid and bone biology. J. Am. Coll. Nutr., 19: 478-486.
Direct Link - Watkins, B.A., Y. Li, K.G. Allen, W.E. Hoffman and M.F. Seifert, 2000. Dietary ratio of (n-6), (n-3) polyunsaturated fatty acids alter the fatty acid composition of bone compartments and biomarkers of bone formation in rats. J. Nutr., 130: 2274-2284.
Direct Link - Yang, L.C., J.B. Wu, G.H. Ho, S.C. Yang, Y.P. Huang and W.C. Lin, 2008. Effects of poly-γ-glutamic acid on calcium absorption in rats. Biosci. Biotechonol. Biochem., 72: 3084-3090.
CrossRefPubMedDirect Link - Ima-Nirwana, S., A. Kiftiah, T. Sariza, M.T. Gapor and B.A.K. Khalid, 1999. Palm vitamin E improves bone metabolism and survival rate in thyrotoxic rats. Gen. Pharm., 32: 621-626.
CrossRef