The Syzygium cumini (Myrtaceae) is a traditional
medicine plant for the treatment of hypoglycemic, antibacterial, anti-HIV
and antidiarrheal activities. The work reached the acute toxicity of
Syzygium cumini and its action on the Central Nervous System (CNS)
because no data in the literature have been found of pharmacological
activity of this plant in the CNS. The seed was extracted with ethyl
acetate and methanol and investigated for its Central Nervous System
activity (CNS) of Albino mice in rota rod and actophotometer at the dose
level of 200 mg/kg and 400 mg/kg. Both the extract exhibited significantly
CNS activity. This study established CNS activity in Syzygium
cumini seed.