Research Article

Effects of Fasting and a Medium Calorie Balanced Diet During the Holy Month Ramadan on Weight, BMI and Some Blood Parameters of Overweight Males

M. Salehi and M. Neghab
Facebook Twitter Digg Reddit Linkedin StumbleUpon E-mail

Fasting during holy month, Ramadan, is a religious obligation for all adult healthy Muslims. During this month Muslims are allowed to eat and drink between sunset and dawn. However, they are not allowed to eat and drink after dawn. To assess the effects of fasting on weight, BMI (Body Mass Index) and some blood indices, we recruited 28 overweight male volunteers aged 20-26 years. They were on a balanced diet of 2000 calories, containing 70 g protein, 350 g carbohydrate and 35.5 g lipid during Ramadan, while they were on a free diet before Ramadan. Subjects were requested to drink more than 6 glasses (about 1.5 L) of water or fruit juice every night between sunset to dawn during Ramadan. Serum levels of glucose, cholesterol, triglyceride as well as weight and BMI were measured in all subjects one day before and after Ramadan. Fasting resulted in significant (p<0.05) decreases in the mean values of both, weight and the BMI. Similarly, the mean values of glucose and cholesterol were significantly decreased in subjects after Ramadan, although none of these decreases reached to a level with pathological significance. Conversely, no significant changes in serum levels of triglyceride were noted.

Related Articles in ASCI
Search in Google Scholar
View Citation
Report Citation

  How to cite this article:

M. Salehi and M. Neghab, 2007. Effects of Fasting and a Medium Calorie Balanced Diet During the Holy Month Ramadan on Weight, BMI and Some Blood Parameters of Overweight Males. Pakistan Journal of Biological Sciences, 10: 968-971.

DOI: 10.3923/pjbs.2007.968.971



During Ramadan, Muslims fast the daylight hours for a month. The duration of restricted food and beverage intake is approximately 12 h/day which makes Ramadan a unique model of intermittent fasting. Many physiological and psychological changes are observed during Ramadan that are probably due to the changes in eating and sleeping patterns (Aksungar et al., 2005; Roky et al., 2004). The experience of fasting is intended to teach Muslims self-discipline and self-restraint and remind them of the plight of the impoverished. Muslims are required to abstain not only from eating and drinking, but also from consuming oral medications and intravenous nutritional fluids during fasting (Roky et al., 2004).

Physiological changes occurring during Islamic fasting have received considerable attention (Shokry, 1986; Dowod, 2004; Maislos et al., 1993; Iraki et al., 1997).

It is known that reduced intake of dietary Saturated Fatty Acids (SFA) and cholesterol lower total and LDL cholesterol concentrations as well as the risk of cardiovascular diseases (Law, 2000; Shahar et al., 2001). Fasting has also been shown to have a small, but statistically significant, impact on fasters' BMI at the end of the fasting periods that was not sustained in non-fasting periods. Similarly, Haddad et al. (1999) have reported significantly lower BMI levels in the vegetarian groups. Moreover, vegetarians have been shown to have lower BMI than meat eaters (Key et al., 1996, 1999). A Mediterranean-style diet has also been proven to be beneficial to weight loss (Azizi and Siahkolah, 2003).

Although in some studies (De Lorenzo et al. 1999), fasting has been reported to reduce the serum lipids and blood sugar, no unanimous agreement exists in this regard.

To the best of authors` knowledge, the effect of Islamic fasting on the weight, BMI, serum cholesterol, glucose and triglyceride levels of overweight individuals have not been extensively studied. Additionally, controversy exists in this regard. The current study was, therefore, conducted in Shiraz, south of Iran, during Rmadan 2002, to better address these issues.


Twenty eight healthy males aged 20 to 26 years (mean age 23.4), voluntarily participated in this study which was performed during Ramadan in Shiraz.

They fasted each day from dawn to sunset for 29 days. The length of each day of fasting was approximately 13 h. Subjects had two main meals. One after sunset (Iftar) and the other just before dawn (Sahar) and they were allowed to eat and drink in the interim. They were on a diet of 2000 calories containing 70 g Protein and 350 g Carbohydrate and 35.5 g fat during Ramadan. However, they were on a free diet before Ramadan.

Abstinence from water is known to cause a slight dehydration during Ramadan (Athar and Habib, 1994). To minimize the likely confounding effects of dehydration on serum cholesterol, glucose and triglyceride, subjects were encouraged to drink at least 6 glasses (1.5 L) of water or natural fruit juice from sunset to dawn.

Blood samples were taken just one day before and one day after Ramadan, after an average fasting time of 13 h. Venous blood was collected in clean glass tubes and allowed to clot at zero degree of centigrade. All specimens were centrifuged and serum was transferred to plastic tubes. Serum glucose, cholesterol and triglyceride were determined by Technical Auto Analyzer.

The weight and height of subjects were measured just one day before and one day after Ramadan.

Body weight was measured to the nearest 0.5 kg. Similarly, body height was measured to the nearest 0.5 cm. BMI was also calculated, using subjects` weight and height data.

Data analysis and statistical procedures: The data were analyzed using student`s paired t-test, or Welch`s alternate t-test (when the standard deviations of two comparable variables with the F-test were significantly different) with a preset probability of p<0.05.


As shown, fasting resulted in significant decreases (p<0.5) in the mean value of both, weight and the BMI (Table 1).

The mean values of glucose and cholesterol were significantly decreased in subjects after Ramadan. However, no significant changes in serum levels of triglyceride were noted (Table 2).

Many studies have reported weight loss during the month of Ramadan fasting (Takruri, 1989. Nomani et al., 1990, 1992). As shown in Table 1, our overweight subjects also experienced a 6% reduction in their weight and BMI during Ramadan. This finding is qualitatively similar to the findings of other studies in which 1.7 kg (Azizi, 1978) 1.8 kg (Sajid et al., 1999), 2 kg (Takruri, 1989) and 3.8 kg (Sulimani, 1988) weight loss have been reported among normal weight individuals during Ramadan.

Similarly, total cholesterol showed a 38% decrease. This statistically significant reduction in serum cholesterol level is also in accord with other studies

Table 1: Anthropometric characteristics of subjects
Image for - Effects of Fasting and a Medium Calorie Balanced Diet During the Holy Month Ramadan on Weight, BMI and Some Blood Parameters of Overweight Males
N/A: Not Applicable, *: significantly different from its corresponding before Ramadan value (paired t-test)

Table 2: Serum glucose, cholesterol and T.G levels in subjects before and after Ramadan
Image for - Effects of Fasting and a Medium Calorie Balanced Diet During the Holy Month Ramadan on Weight, BMI and Some Blood Parameters of Overweight Males
NS: Non Significant, * significantly different from its corresponding before Ramadan value (paired t-test)

(Katerina et al., 2003) in which fasters presented 12.5% lower-end-total cholesterol value compared to their control counterparts.

Increase in total cholesterol levels during Ramadan seldom occurs (Laajam, 1990) and few studies have reported increases in high-density-lipoprotein (Adlouni et al., 1998; Maislos et al., 1998).

Compared to other studies (Azizi, 1978; Sajid et al., 1999; Takruri, 1989; Sulimani, 1988; Katerina et al., 2003) a combination of sufficient fluid intake in conjunction with a medium calorie balanced diet, as practiced in our study, more efficiently reduced the BMI, weight and serum cholesterol levels. This could be explained, at least in part, by the fact that drinking relatively large amounts of fluids reduces the normal appetite, thereby restricts food consumption.

Our data also showed a non significant slight increase in serum TG levels in fasting overweight individuals. This non significant increase is also consistent with the observations of other authors who found non significant elevations in end-fasting serum TG and VLDL that could be attributed to the lipolytic effects of prolonged fasting (De Lorenzo et al., 1999; Nagra et al., 1998).

Few studies have investigated the effects of Ramadan fasting on serum glucose levels (Haouri et al., 1997; Azizi and Rasouli, 1987). Some have shown a mild increase (Scot, 1981) or variation in serum glucose concentration (Davidson, 1979; Khogheer et al., 1981).

Fasting is known to be associated with psychological effects. There is a peace and tranquility for those who fast during the month of Ramadan. Personal hostility is at a minimum and the crime rate decreases. This psychological improvement could be related to better stabilization of blood glucose during fasting as hyperglycemia after eating, aggravates behavior changes.

(Athar and Habib, 1994). As illustrated in Table 2, serum glucose level in this study also showed a 15% decrease in overweight subjects. Qualitatively similar findings have been reported by authors in a previous study (Ravanshad et al., 1999) in healthy adult male aged 16-67 years.

In conclusion, our findings demonstrate that consumption of a medium calorie balanced diet in conjunction with sufficient fluid intake during Ramadan and fasting may significantly decrease serum levels of glucose, cholesterol, as well as weight and BMI. Although none of these decreases reaches pathological level.


  1. Adlouni, A., N. Ghalim, R. Saile, N. Had, H.J. Parra and A. Benslimane, 1998. Beneficial effect on serum apo A1, APO B and Lp A1 levels of Ramadan fasting. Clin. Chim. Acta, 271: 179-189.

  2. Aksungar, F.B., A.E. Sengul U.O. Teskin and A. Gursel, 2005. Effects of intermittent fasting on serum lipid levels, coagulation status and plasma homocysteine levels. Eur. J. Nut. Diet, 49: 77-82.
    CrossRef  |  Direct Link  |  

  3. Athar, S. and M. Habib, 1994. Management of stable type 2 diabetes mellitus NIDDM during Islamic fasting in Ramadan, 1994. Proceedings of the 1st International Congress on Health and Ramadan, Jan. 19-22, Casablanca, Morocco.

  4. Azizi, F., 1978. Effect of dietary composition on fasting induced changes in serum thyroid hormones and thyrotropin. Metabolism, 27: 935-945.

  5. Azizi, F. and H.A. Rasouli, 1987. Erum glucose, bilirubin, calcium, phosphorus, protein and albumin concentrations during Ramadan. Med. J. IR. Iran, 1: 38-41.

  6. Azizi, F. and B. Siahkaloh, 2003. Ramadan fasting and diabetes mellitus. Arch. Iran. Med., 6: 237-242.
    Direct Link  |  

  7. Burr, M.L. and B.K. Butland, 1988. Heart disease in British vegetarians. Am. J. Clin. Nutr., 48: 830-832.
    Direct Link  |  

  8. Davidson, J.C., 1979. Muslims, Ramadans and diabetes mellitus. Br. Med. J., 2: 1511-1512.
    Direct Link  |  

  9. De Lorenzo, A., P. Petrone-De Luca, S.F. Guido, G.C. Maria, R. Paolo and B. Aldo, 1999. Effects of weight loss on body composition and pulmonary function. Respiration J., 66: 407-412.
    CrossRef  |  Direct Link  |  

  10. Dowod, T., 2004. Effect of ramadan fasting on blood lipids and sugar. Pak. J. Med. Sci., 20: 308-310.
    Direct Link  |  

  11. El-Ati, J., C. Beji and J. Danguir, 1995. Increased fat oxidation during Ramadan fasting in healthy women: An adaptive mechanism for body-weight maintenance. Am. J. Clin. Nutr., 62: 302-307.

  12. Fedail, S.S., D. Murphy, S.Y. Salih, C.H. Bolton and R.F. Harvey, 1982. Changes in Certain blood constituents during Ramadan. Is. J. Clin. Nutr., 36: 350-353.

  13. Haddad, E.H., S.B. Lee, D.K. James, W.H. Richard and R.P. Warren, 1999. Dietary intake and biochemical, hematological and immune status of vegans compared with no vegetarians. Am. J. Clin. Nutr., 70: 586S-593S.
    PubMed  |  Direct Link  |  

  14. Haouri, M., F. Haourai-Oukerro and A. Mebazaa et al., 1997. Circadian evolution of serum level of glucose, insulin, cortisol and total proteins in healthy, fasting volunteers. Proceedings of the 2nd International Congress on Health and Ramadan, Dec. 1-3, Istanbul, Turkey.

  15. Iraki, L., A. Bogdan, F. Hakkou, N. Amrani, A. Abkari and Y. Touitou, 1997. Ramadan diet restrictions modify the circadian time structure in humans. A study on plasma gastrin, insulin, glucose and calcium and on gastric pH. J. Clin. Endocrinol. Metab., 82: 1261-1273.
    Direct Link  |  

  16. Katerina, O., E. Nikolaos, K. Manolis, D. George and G. Anthony, 2003. Effects of Greek Orthodox Christian Church Fasting on Serum Lipids and Obesity. BMC Public Health, Paris, pp: 3-16

  17. Key, T. and G. Davey, 1996. Prevalence of obesity is low in people who do not eat meat. BMC., 313: 816-817.
    Direct Link  |  

  18. Key, T.J., G.K. Davey and P.N. Appleby, 1999. Health benefits of a vegetarian diet. Proc. Nutr. Soc., 58: 271-275.
    CrossRef  |  PubMed  |  Direct Link  |  

  19. Khogheer, Y., M.I. Sulaiman and S.F. Al-Fayez, 1987. Ramadan fasting state of controls. Ann. Saudi Med., 7: 5-6.

  20. Laajam, M.A., 1990. Ramadan fasting and non-insulin-dependent diabetes: Effect on metabolic control. East Afr. Med. J., 67: 732-736.
    PubMed  |  Direct Link  |  

  21. Law, M., 2000. Dietary fat and adult diseases and the implications for childhood nutrition: An epidemiologic approach. Am. J. Clin. Nutr., 72: 1291S-1296S.
    Direct Link  |  

  22. Maislos, M., N. Khamaysi, A. Assali, Y. Abou-Rabiah, I. Zvili and S. Shany, 1993. Marked increase in plasma high-density lipoprotein cholesterol after prolonged fasting during Ramadan. IS. J. Clin. Nutr., 57: 640-642.

  23. Maislos, M., Y. Abou-Rabiah, I. Zuili, S. Iordash and S. Shany, 1998. Gorging and plasma HDL-cholesterol: The Ramadan model. Eur. J. Clin. Nutr., 52: 127-130.
    Direct Link  |  

  24. Nagra, S.A., Z. Rahman and J. Mehmood et al., 1998. Study of some biochemical parameters in young women as affected by Ramadan fasting. Int. J. Ramadan Fasting Res., 2: 1-5.

  25. Nomani, M.Z., M.H. Hallak and I.P. Siddiqui, 1990. Effect of Ramadan fasting on plasma uric acid and body weight in healthy men. J. Am. Dietetic Association, 90: 1435-1436.
    PubMed  |  

  26. Nomani, M.Z.A., S.K. Baloch and I.P. Siddiqui, 1992. Changes in serum cholesterol level and dietary vegetable fat at restricted energy intake condition during Ramadan fasting. Int. J. Sci. Technol., 4: 30-36.

  27. Ravanshad, S.H., M. Salehi, E. Setoudeh, B. Zeighami and S.A. Ayatollahi, 1999. Effect of fastiung On serum glucose, lipids and keton bodies concentration during Ramadan in Arsanjan, Iran. Med. J. Iran Hosp., 2: 23-28.

  28. Roky, R., I. Houti, S. Moussamih, S. Qotbi and N. Aadil, 2004. Physiological and chronobiological changes during ramadan intermittent fasting. Ann. Nutr. Metab., 48: 296-303.
    PubMed  |  Direct Link  |  

  29. Sajid, K.M., M. Akhtar and G.O. Malik, 1991. Ramadan fasting and thyroid hormone profile. J. Pak. Med. Assoc., 41: 213-216.

  30. Scott, T.G., 1981. The effect of Muslim fast of Ramadan on routine laboratory investigation. King Abdulaziz Med. J., 1: 23-35.

  31. Shahar, D.R., N. Yerushalmi, F. Lubin, P. Froom, A. Shahar and E. Kristal-Boneh, 2001. Seasonal variations in dietary intake affect the consistency of dietary assessment. Eur. J. Epidemiol., 17: 129-133.
    CrossRef  |  Direct Link  |  

  32. Shoukry, M.I., 1986. Effect of fasting in Ramadan on plasma lipoproteins and apportions. Saudi. Med. J., 7: 561-565.

  33. Suleiman, R.A., 1988. Effect of Ramadan fasting on thyroid function in Healthy male individuals. Nutr. Res., 8: 549-552.

  34. Takruri, H.R., 1989. Effect of fasting in Ramadan on body weight. Saudi. Med. J., 10: 491-494.

©  2022 Science Alert. All Rights Reserved