Subscribe Now Subscribe Today
Research Article
 

Biological Evaluation of Some Acylated Derivatives of D-mannose



Abul K.M.S. Kabir , Pijush Dutta and M.N. Anwar
 
Facebook Twitter Digg Reddit Linkedin StumbleUpon E-mail
ABSTRACT

A number of D-mannose derivatives were evaluated for in vitro antibacterial activity against eleven human pathogenic bacteria. These compounds were also screened for in vitro antifungal activity against six plant pathogenic fungi. It was observed from the study that the tested acylated derivatives of D-mannose exhibited moderate to good antibacterial and antifungal activities. The acylated D-mannose derivatives were found to be more effective against fungal phytopathogens than those of the bacterial strains. For comparative study, the biological activity of two standard antibiotics (Ampicillin and Nystatin) were also measured. It was found that the antimicrobial functionality of D-mannose increased with the introduction of various acyl substituents and in some cases, this functionality was greater than or comparable to the antibiotics studied.

Services
Related Articles in ASCI
Similar Articles in this Journal
Search in Google Scholar
View Citation
Report Citation

 
  How to cite this article:

Abul K.M.S. Kabir , Pijush Dutta and M.N. Anwar , 2004. Biological Evaluation of Some Acylated Derivatives of D-mannose. Pakistan Journal of Biological Sciences, 7: 1730-1734.

DOI: 10.3923/pjbs.2004.1730.1734

URL: https://scialert.net/abstract/?doi=pjbs.2004.1730.1734

REFERENCES
1:  Singh, H., K.N. Shukla, R. Dwivedi and L.D.S. Yadav, 1990. Clycloaddition of 4-amino-3-mercepto-1,2,4-triazole to heterocumulenes and antifungal activity of the resulting 1,2,4-triazolo[3,4-c]-1,2-dithia-4,5-diazines. J. Agric. Food. Chem., 38: 1483-1486.

2:  Andary, C., R. Wylde, C. Laffite, G. Privat and F. Winternitz, 1982. Structures of verbascoside and orobanchoside, caffeic acid sugar esters from Orobanche rapum-genistae. Phytochemistry, 21: 1123-1127.
CrossRef  |  Direct Link  |  

3:  Gupta, R., S. Paul, A.K. Gupta, P.L. Kachroo and S. Bani, 1997. Synthesis and biological activities of some 2-substituted phenyl-3-(3-alkyl/aryl-5,6-dihydro-s-triazolo[3,4-b][1,3,4] thiazol-6-yl) indoles. Indian J. Chem., 36: 707-710.
Direct Link  |  

4:  Kabir, A.K.M.S., M.M. Matin, M.M.R. Bhuiyan and M.A. Rahim, 2001. Synthesis and characterization of some acylated derivatives of D-mannose. Chittagong Univ. J. Sci., 25: 65-73.

5:  Kabir, A.K.M.S., M.M. Matin and A.F.M. Sanaullah, 2002. Regioselective synthesis and characterization of some lyxose derivatives. Ceylon J. Sci., 9: 9-14.

6:  Kabir, A.K.M.S., M.M. Matin, M.J. Alam and M.A. Manchur, 2000. Synthesis and antimicrobial activities of some D-glucose derivatives. J. Bangladesh Chem. Soc., 13: 107-115.

7:  Kabir, A.K.M.S., M.M. Matin, A.F.M. Sanaullah, M.A. Sattar and M.S. Rahman, 2001. Antimicrobial activities of some lyxoside derivatives. Bangladesh J. Microb., 18: 89-95.

8:  Kabir, A.K.M.S., M.M. Matin, M. Ali and M.N. Anwar, 2003. Comparativestudies on selective acylation and antimicrobial activities of some D-glucofuranose derivatives. J. Bangladesh Aca. Sci., 27: 43-50.

9:  Kabir, A.K.M.S, P. Dutta and M.N. Anwar, 2003. Synthesis of some D-mannose derivatives for antimicrobial screening studies. Chittagong Univ. J. Sci.

10:  Bauer, A.W., W.M.M. Kirby, J.C. Sherris and M. Turck, 1966. Antibiotic susceptibility testing by a standardized single disk method. Am. J. Clin. Pathol., 45: 493-496.
CrossRef  |  PubMed  |  Direct Link  |  

11:  Grover, R.K. and J.D. Moore, 1962. Toximetric studies of fungicides against the brown rot organisms, Sclerotinia fructicola and S. laxa, Phytopathology, 52: 52-52.

12:  Miah, M.A.T, H.U. Ahmed, N.R. Sharma, A. Ali and S.A. Miah, 1990. Antifungal activity of some plant extracts. Bangladesh J. Bot., 19: 5-10.

©  2021 Science Alert. All Rights Reserved