|
|
|
| |
Research Article
|
|
Purification and Identification of Antibacterial Compound of Atung (Parinarium glaberrimum Hassk) Seed |
|
|
Erynola Moniharapon ,
Samir A.M. Abdelgaleil ,
Trijunianto Moniharapon ,
Yuka Watanabe
and
Fumio Hashinaga
|
| |
|
|
ABSTRACT
|
The present study was carried out to isolate and identify antibacterial compound of atung (Parinarium glaberrimum Hassk) seed. Based on the MS and NMR spectroscopic data, the chemical structure of compound was determined as nonanedioic acid (azelaic acid). This compound exhibited considerably strong antibacterial activities against six tested strains of food spoilage and pathogenic bacteria with 20-30 μg mL-1 of minimum inhibitory concentration.
|
|
| |
|
|
|
|
|
REFERENCES |
1: Moniharapon, T., S.T. Soekarto, S. Putro and R.R. Nitibaskara, 1993. Atung seed as preservatives of Penaeus monodon Fab fresh shrimp. J. Ilmu Pertanian Indonesia, 3: 48-52.
2: Dunstan, C.A., Y. Noreen, G. Serrano, P.A. Cox, P. Perera and L. Bohlin, 1997. Evaluation of some Samoan and Peruvian medicinal plants by prostaglandin biosynthesis and rat ear oedema assays. J. Ethnopharmacol., 57: 35-36.
CrossRef | Direct Link |
3: Moniharapon, E. and F. Hashinaga, 2004. Antimicrobial activity of atung (Parinarium glaberrimum Hassk) fruit extract. Pak. J. Biol. Sci., 7: 1057-1061.
CrossRef | Direct Link |
4: Nishina, A.K., K. Hasegawa, T. Uchibori, H. Seino and T. Osawa, 1991. 2, 6-dimethy-p-benzoquinone as an antibacterial substance in the bark of Phyllostachys heterocycla Var. Pubescens, a species of thick-stemmed bamboo. Agric. Food Chem., 39: 266-269.
5: Kim, J., M.R. Marshall and C.I. Wei, 1995. Antibacterial activity of some essential oil components against five foodborne pathogens. J. Agric. Food Chem., 43: 2839-2845.
CrossRef | Direct Link |
6: Nishina, C., N. Enoki, S. Tawata, A. Mori, K. Kobayashi and M. Fukushima, 1987. Antibacterial activity of flavonoids against Staphylococcus epidermidis a skin of bacterium. Agric. Biol. Chem., 51: 139-143.
Direct Link |
7: Nguyen V.C., T. Kurata, H. Kato and M. Fujimaki, 1982. Antimicrobial activity of kumazasa (Sasa albo marginata). J. Agric. Biol. Chem., 46: 971-978.
8: Nakayama, R., M. Murata, S. Homma and K. Aida, 1990. Antibacterial compounds from Eucalyptus perriniana. Agric. Biol. Chem., 54: 231-232.
9: Cho, J.Y., H.K. Kim, S.J. Ma, J.H. Moon and K.H. Park, 2000. Isolation and identification of azelaic acid and 3, 4-dihydroxybenzoic acid from buckwheat hull as antimicrobial substances. Food Sci. Biotechnol., 9: 313-316.
10: Nazzaro-Porro, M., S. Passi and M. Picardo, 1983. Beneficial effect 15% azelaic acid cream on Acne vulgaris. Br. J. Dermatol., 109: 45-48.
11: Graupe, K., W.J. Cunliffe, H.P.M. Gollnick and R.P. Saumseil, 1996. Efficacy and safety of topical azelaic acid (20%) cream: An overview of results from European clinical trials and experimental reports. Cutis, 57: 20-35.
PubMed |
12: Carmichael, A.J., R. Marks and K. Graupe, 1993. Topical azelaic acid in the treatment of rosacea. J. Dermatol. Treat., 4: 19-22.
13: Nazzaro-Porro, M., 1993. The use of azelaic acid in hyperpigmentation. Rev. Contemp. Pharmacother., 4: 415-423.
14: Breatnach, A.S., 1996. Melanin hyperpigmentation of skin: Melasma, topical treatment with azelaic acid and other therapies. Cutis, 57: 36-45.
15: Mingrone, G., A.V. Greco, M. Nazzaro-Porro and S. Passi, 1983. Toxicity of azelaic acid. Drugs Clin. Exp. Res., 9: 447-455.
16: Topert, M., P. Rach and F. Siegmund, 1989. Pharmacology and Toxicology of Azelaic Acid. In: Azelaic Acid: A New Therapeutic Agent, Breatnach, A.S., K. Graupe and G. Stingl (Eds.). IGBP, Stockholm, pp: 14-19.
17: Passi, S., 1993. Pharmacology and pharmakinetics of azelaic acid. Rev. Contemp. Pharmacother., 4: 441-447.
|
|
|
 |
Subscribe Today
