ABSTRACT
In this study isolated perfused rat muscle was used to examine the direct effect of temperature changes on the eccentric contraction-induced force and desmin loss. The left medial gastrocnemius muscle was separated and the entire lower limb was transferred into a prewarmed (35°C) organ bath. Temperature was adjusted to 31 or 39°C before and during eccentric contractions. Maximal isometric force and desmin loss were measured after 15 isometric or eccentric contractions. According to our data, organ bath temperature changes before or during eccentric contractions had no significant effect on force loss. However, a strong correlation between desmin loss and temperature changes before (r = 0.93, p<0.05) and during (r = 0.87, p<0.05) eccentric contractions was observed. Present results suggest that cooling before or during eccentric contractions may decrease desmin loss.
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Behnoosh Vasaghi-Gharamaleki, Mansoor Keshavarz, Shahryar Gharibzadeh, Masoud Sotodeh, Hamidreza Marvi, Javad Mosayebnejad and Ismail Ebrahimi Takamjani, 2008. The Influence of Temperature Alterations on Eccentric Contraction-Induced sometric Force and Desmin Loss in Rat Medial Gastrocnemius Muscle. Journal of Medical Sciences, 8: 162-169.
DOI: 10.3923/jms.2008.162.169
URL: https://scialert.net/abstract/?doi=jms.2008.162.169
DOI: 10.3923/jms.2008.162.169
URL: https://scialert.net/abstract/?doi=jms.2008.162.169
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