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Journal of Medical Sciences

Year: 2008 | Volume: 8 | Issue: 2 | Page No.: 102-110
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Research Article

Some Complementary Hypoglycemic Supplements from Grains and Legumes for the Management of Type 2 Diabetes Mellitus

Lobna A. Ghattas, Laila M. Hanna, Salwa T. Tapozada and Salwa M. El-Shebini

ABSTRACT

In this study the aim was to introduce and incorporate some of the traditional plants as test foods supplements: namely wheat, two forms of fenugreek (both powdered and germinated), lupine and chickpea. Also, the combination of two test foods in the same mixture in the form of biscuits in which whole wheat is the main constituent, to serve as adjuncts to the orthodox medical treatment, to aid in the rapid normalization and consequent stabilization of the blood glucose levels. Volunteers of apparently uncomplicated type 2 diabetic patients recruited from the National Research Center, Cairo Egypt. They were divided to 9 groups and instructed to follow a low hypocaloric balanced diet. Eight groups instructed to substituted known amounts of the above mentioned nutrients for part of their daily breakfast bread for one week for each test food item calculated according to their carbohydrate content. The last group followed the diet only. Mean blood sugar levels were decreased at all time points in the glucose tolerance test. Significant values were noted on the glucose curve of lupine, fenugreek powdered, partially decorticated belila and at all the points of the curve in the data of two biscuits 1 and 2 in comparison to basal levels. A significant fall in serum insulin levels after 2 h were observed in lupine with a percentage decrease (-39.93%) and after introducing partially decorticated wheat (belila) with a percentage decrease of -44.94% after 2 h. Data for HBA1c showed a numerical decrease for all groups except for that of lupine and a significant loss was found for whole wheat and biscuit 1. In conclusion various combinations of different grains and legumes led to a beneficial hypoglycemic effect together with the improvement of glucose, insulin and glycosylated haemoglobin in type 2 diabetics.
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