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(1→3)-β-D-Glucans from Libyan Dates (Phoenix dactylifera L.) and Their Anti-cancer Activities



Omar Ishurd , Faraj Zgheela , Adel Kermagia , Nansur Flefleaa , Mohamed Elmabruka , John F. Kennedy and Ahmed Ashour
 
ABSTRACT

A glucan of cellular origin has been isolated from Libyan dates (Phoenix dactylifera L.) and the structure of the purified glucan characterised using derivatisation methods including methylation, periodate oxidation and acetolysis. Glucans were found to exhibit potent antitumour activity; this activity could be correlated to their (1→3)-β-D-glucan linkages. This is the first report on studies of antitumour active compounds occurring in dates.

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  How to cite this article:

Omar Ishurd , Faraj Zgheela , Adel Kermagia , Nansur Flefleaa , Mohamed Elmabruka , John F. Kennedy and Ahmed Ashour , 2007. (1→3)-β-D-Glucans from Libyan Dates (Phoenix dactylifera L.) and Their Anti-cancer Activities. Journal of Biological Sciences, 7: 554-557.

DOI: 10.3923/jbs.2007.554.557

URL: https://scialert.net/abstract/?doi=jbs.2007.554.557

REFERENCES
Ahmed, I.A. and R.K. Robinson, 1999. The ability of date extracts to support the production of aflatoxins. Food Chem., 66: 307-312.
Direct Link  |  

Ishurd, O., C. Sun, P. Xiao, A. Ashour and Y. Pan, 2002. A neutral β-D-glucan from dates of the date palm, Phoenix dactylifera L. Carbohydr. Res., 337: 1325-1328.
Direct Link  |  

Ishurd, O., M. Zahid, V.U. Ahmad and Y.J. Pan, 2001. Isolation and structure analysis of a glucomannan from the seeds of Libyan dates. J. Agric. Food Chem., 49: 3772-3774.
Direct Link  |  

Misaki, A., M. Kakuta, T. Sasaki, M. Tanaka and H. Miyagi, 1981. Studies on interrelation of structure and antitumor effects of polysaccharides: Antitumor action of periodate-modified, branched (163)-β-D-glucan of Auricularia auricula-judae and other polysaccharides containing (l63)-glycosidic linkages. Carbohydr. Res., 92: 115-129.

Misaki, A., M. Nasu, Y. Sone, E. Kishida and C. Kinoshita, 1986. Comparison of structure and antitumor-activity of polysaccharides isolated from Fukurotake, the fruitimg body of V. volvacea. Agric. Biol. Chem., 50: 2171-2183.

Puri, A., R. Sahai, K.L. Singh, R.P. Saxena, J.S. Tandon and K.C. Saxena, 2000. Immunostimulant activity of dry fruits and plants materials used in Indian traditional medical system for mother after child birth and invalids. J. Ethnopharmacol., 71: 89-92.
Direct Link  |  

Rinaudo, M. and M. Vincendon, 1982. 13C NMR structural investigation of scleroglucan. Carbohydr. Polym., 2: 135-144.

Sasaki, T., J. Hamuro, G. Chihara and M. Amano, 1970. Radioautographic study on distribution of a polysaccharide with antitumoral activity in mice. Gann, 61: 589-591.

Shinwari, M.A., 1992. Encyclopedia of Food Science, Food Technology and Nutrition. Academic Press, London, pp: 1300-1305.

Usui, T., Y. Iwasak and T. Mizuno, 1983. Isolation and characterization of antitumor active β-D-glucans from the fruit bodies of Ganoderma applanatum. Carbohydr. Res., 115: 273-280.

Yoshioka, Y., R. Tabeta, H. Saito, N. Uehara and F. Fukuoka, 1985. Antitumor polysaccharides from P. ostreatus (Fr.) Quel.: Isolation and structure of a β-glucan. Carbohydr. Res., 140: 93-100.
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