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Journal of Biological Sciences

Year: 2004 | Volume: 4 | Issue: 5 | Page No.: 687-693
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Research Article

Important Therapeutic Uses of Sea Buckthorn (Hippophae): A Review

Alam Zeb

ABSTRACT

Sea buckthorn is a deciduous species, widely distributed all over the world, including Pakistan. It contains different kinds of nutrients and bioactive substances such as vitamins, carotenoids, flavonoids, polyunsaturated fatty acids, free amino acids and elemental components etc. These components vary substantially among populations, origins or subspecies, however their presence is more important for the health of individual. The clinical trials and scientific studies during the 20th century confirm medicinal and nutritional value of sea buckthorn. The present study describe some areas of research that have been important points, for example in cancer therapy, cardiovascular diseases, treatment of gastrointestinal ulcers, skin disorder and as a liver protective agent. A lot of research work is still need to clarify the mechanism of curing these conditions in molecular and cellular levels.
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REFERENCES

  1. Li, T.S.C. and W.R. Schroeder, 1996. Sea buckthorn (Hippophae rhamnoide L.): A multipurpose plant. Hort. Technol., 6: 370-380.
  2. Beveridge, T., J.E. Harrison and J. Drover, 2002. Processing effects on the composition of sea buckthorn juice from H. rhamnoides. L. Cv. Indian Summer. J. Agric. Food Chem., 50: 113-116.
  3. Zeb, A., 2004. Chemical and nutritional constituents of sea buckthorn juice. Pak. J. Nutr., 3: 99-106.
    CrossRefDirect Link
  4. Beveridge, T., T.S.C. Li, B.D. Oomah and A. Smith, 1999. Sea buckthorn products: Manufacture and composition. J. Agric. Food Chem., 47: 3480-3488.
    CrossRefPubMedDirect Link
  5. Tang, X. and P. Tiderstedt, 2001. Variation of physical and chemical characters within an elite sea buckthorn (Hippophae ramnoides L.) breeding population. Sci. Hort., 88: 203-214.
  6. Yao, Y., P.M.A. Tigerstedt and P. Joy, 1992. Variation of vitamin C concentration and character correlation and between and within natural sea buckthorn (H. rhamnoides L.) Populations. Acta Agric. Scand., 42: 12-17.
  7. Jeppsson, N. and X.Q. Gao, 2000. Changes in the contents of kaempherol, quercetin and L-ascorbic acid in sea buckthorn berries during maturation. Agric. Food Sci., 9: 17-22.
  8. Kallio, H., B. Yang and P. Peippo, 2002. Effects of different origins and harvesting time on vitamin C, tocopherols and tocotrienols in sea buckthorn (Hippophae rhamnoides) berries. J. Agric. Food Chem., 50: 6136-6142.
    CrossRefPubMedDirect Link
  9. Chen, T., 1988. Studies of the biochemical composition of Hippophae and its quality assessment in Gansu Province. Hippophae, 1: 19-26.
  10. Makinen, K.K. and E. Soderling, 1980. A quantitative study of mannitol, sorbitol, xylitol and xylose in wild berries and commercial fruits. J. Food Sci., 45: 367-374.
  11. Zeb, A. and S. Mehmood, 2004. Carotenoids contents from various sources and their potential health applications. Pak. J. Nutr., 3: 197-202.
  12. Pintea, A., A. Marpeau, M. Faye, C. Socaciu and M. Gleizes, 2001. Polar lipid and fatty acid distribution in caroteno-lipoprotein complexes extracted from sea buckthorn fruits. Phytochem. Analysis, 5: 293-298.
  13. Yang, B.R., 2001. Lipophilic components of sea buckthorn (Hippophae rhamnoides) seeds and berries and physiological effects of sea buckthorn oils. Ph.D. Thesis, University of Turku, Finland.
  14. Berezhnaya, G.A., O.V. Ozerinina, I.P. Yeliseev, V.D. Tsydendambaev and A.G. Vereshchagin, 1993. Developmental changes in the absolute content and fatty acid composition of acyl lipids of sea buckthorn fruits. Plant Physio. Biochem., 31: 323-332.
  15. Hakkinen, S.H., S.O. Karenlampi, I.M. Heinonen, H.M. Mykkanen and A.R. Torronen, 1999. Content of the flavonols quercetin, myricetin and kaempferol in 25 edible berries. J. Agric. Food Chem., 47: 2274-2279.
  16. Yang, B. and H.P. Kallio, 2001. Fatty acid composition of lipids in sea buckthorn (Hippophae rhamnoides L.) berries of different origins. J. Agric. Food Chem., 49: 1939-1947.
  17. Yang, B.R. and H. Kallio, 2002. Effects of harvesting time on triacylglycerols and glycerophospholipids of sea buckthorn (H. rhamnoides L.) Berries of different origins. J. Food Composit. Anal., 15: 143-157.
  18. Yang, B., R.M. Karlsson, P.H. Oksman and H.P. Kallio, 2001. Phytosterols in sea buckthorn (Hippophae rhamnoides L.) berries: Identification and effects of different origins and harvesting times. J. Agric. Food Chem., 49: 5620-5629.
    CrossRefDirect Link
  19. Weller, P. and D.E. Breithaupt, 2003. Identification and quantification of zeaxanthin esters in plants using liquid chromatography-mass spectrometry. J. Agric. Food Chem., 51: 7044-7049.
  20. Luhua, Z., T. Ying, Z. Zhengyu and W. Guangji, 2004. Determination of alpha-tocopherol in the traditional Chinese medicinal preparation sea buckthorn oil capsule by non-aqueous reversed phase-HPLC. Chem. Pharm. Bull. (Tokyo), 52: 150-152.
  21. Puupponen-Pimia, R., L. Nohynek, C. Meier, M. Kahkonen, M. Heinonen, A. Hopia and K.M. Oksman-Caldentey, 2001. Antimicrobial properties of phenolic compounds from berries. J. Applied Microbiol., 90: 494-507.
    CrossRefPubMedDirect Link
  22. Tabassum, B., M.T. Javed, N. Abbas, Alia, S. Pervaiz and K. Almas, 1998. Determination of serum vitamin-A, β-carotene, total proteins and fractions in women within 24 hours of delivery from different age and socioeconomic groups. Pak. J. Biol. Sci., 1: 29-32.
    CrossRefDirect Link
  23. Sadek, I. A. and A. Abou-Gabal, 1999. β-carotene lock the effect of acrylamide on liver in the egyptian toad. Pak. J. Biol. Sci., 2: 1100-1101.
  24. Rosch, D., M. Bergmann, D. Knorr and L.W. Kroh, 2003. Structure-antioxidant efficiency relationships of phenolic compounds and their contribution to the antioxidant activity of sea buckthorn juice. J. Agric. Food Chem., 51: 4233-4239.
    PubMed
  25. Yuzhen, Z. and W. Fuheng, 1997. Sea buckthorn flavonoids and their medical value. Hippophae, 10: 39-41.
  26. Mingyu, X., 1994. Anticancer effects of and direction of research on Hippophae. Hippophae, 7: 41-43.
  27. Zhang, P., 1989. The anti-cancer activities of Hippophae seed oil and its effect on the weight of the immunological organs. Hippophae, 3: 31-31.
  28. Nersesian, A.K., V.N. Zilfian, V.A. Kumkumadzhian and N.V. Proshian, 1990. Antimutagenic properties of sea buckthorn oil. Genetika, 26: 378-380.
  29. Agrawala, P.K. and H.C. Goel, 2002. Protective effect of RH-3 with special reference to radiation induced micronuclei in mouse bone marrow. Indian J. Exp. Biol., 40: 525-530.
    PubMed
  30. Chen, Y., 2003. Study on the effects of the oil from Hippophae rhamnoides in hematopoiesis. Chinese Herbal Drugs, 26: 572-575.
  31. Yu, L., 1993. Effects of Hippophae rhamnoides juice on immunologic and antitumor functions. Acta Nutrimenta Sinica, 15: 280-283.
  32. Zhong, F., 1989. Effects of the total flavonoid of Hippophae rhamnoides on nonspecific immunity in animals. Shanxi Med. J., 18: 9-10.
  33. Ismail, A.S., 1999. Impact on vitamins, nutrition and cancer in amphibian. Pak. J. Biol. Sci., 2: 1655-1662.
  34. Hang, M., 1987. Treatment of ischemic heart diseases with flavonoids of Hippophae rhamnoides. Chin. J. Card., 15: 97-99.
  35. Cheng, J., K. Kondoa, Y. Suzuki, Y. Ikeda, X. Meng and K. Umemura, 2003. Inhibitory effects of total flavones of Hippophae rhamnoides on thrombosis in mouse femoral artery and In vitro platelet aggregation. Life Sci., 72: 2263-2271.
  36. Xiao, Z., W. Peng, B. Zhu and Z. Wang, 2003. The inhibitory effect of total flavonoids of Hippophae on the activation of NF-kappa β by stretching cultured cardiac myocytes. Sichuan Univ. Med. J., 34: 283-285.
  37. Mohammad Salahat, A., S. Husni Farah and S. Yahya Al-Degs, 2002. Importance of HDL cholesterol as predictor of coronary heart disease in Jordan population: The role of HDL-subfractions in reverse cholesterol transport. Pak. J. Biol. Sci., 5: 1189-1191.
    CrossRefDirect Link
  38. Yang, C., 1995. A clinical study of reducing fat and anti-oxidation of dried Hippophae emulsion. Hippophae, 8: 33-35.
  39. Eccleston, C., Y. Baoru, R. Tahvonen, H. Kallio, G.H. Rimbach and A.M. Minihane, 2002. Effects of an antioxidant-rich juice (sea buckthorn) on risk factors for coronary heart disease in humans. J. Nutr. Biochem., 13: 346-354.
  40. Ivanov, V.N. and L.P. Nikitina, 1973. Effect of sea buckthorn oil on certain indices of lipid metabolism in experimental atherosclerosis. Vopr Pitan., 6: 13-16.
  41. Rice-Evans, C. and N.J. Miller, 1994. Total antioxidant status in plasma and body fluids. Methods Enzymol., 234: 279-293.
    PubMed
  42. Xing, J., B. Yang, Y. Dong, B. Wang, J. Wang and H. Kallio, 2002. Effects of sea buckthorn (Hippophae rhamnoides L.) seed and pulp oils on experimental models of gastric ulcer in rats. Fitoterapia, 73: 644-650.
    CrossRef
  43. Suleyman, H., L.O. Demirezer, M.E. Buyukokuroglu, M.F. Akcay, A. Gepdiremen, Z.N. Banoglu and F. Gocer, 2001. Antiulcerogenic effect of Hippophae rhamnoides L. Phytother Res., 15: 625-627.
    CrossRef
  44. Suleyman, H., M.E. Buyukokuroglu, M. Koruk, F. Akcay, A. Kiziltunc and A. Gepdiremen, 2001. The effects of Hippophae rhamnoides L. Extract on ethanol induced gastric lesion and gastric tissue glutathione level in rats: A comparative study with melatonin and omeprazole. Indian J. Pharm., 33: 77-81.
  45. Nuzov, B.G., 1991. Effect of miliacin oil in the treatment of trophic ulcers. Patol. Fiziol. Eksp. Ter., 1: 34-35.
  46. Gao, Z.L., X.H. Gu, F.T. Cheng, F.H. Jiang, 2003. Effect of sea buckthorn on liver fibrosis: A clinical study. World J. Gastroenterol., 9: 1615-1617.
    PubMed
  47. Cheng, T., 1990. Acute toxicity of flesh oil of Hippophae rhamnoides and its protection against experimental hepatic injury. J. Trad. Chin. Med., 15: 45-47.
  48. Zao, T.D., Z.X. Cheng, X.Y. Liu, J.Y. Shao, L.J. Ren, L. Zhang and W.C. Chen, 1987. Protective effect of the sea buckthorn oil for liver injury induced by CCl4. Zhongcaoyao, 18: 22-24.
  49. Huang, D.L., X.Z. Chang, H.N. Gui, Y.D. Tian, L.X. Chen, Z.P. Li and L. Xing, 1991. Analysis of 156 cases of chronic hepatitis treated with sea buckthorn. Zhongxiyi Jiehe Zazhi., 11: 697-698.
  50. Zhao, Y., 1994. Clinical effects of Hippophae seed oil in the treatment of 32 burn cases. Hippophae, 7: 36-37.
  51. Goel, H.C., J. Prasad, S. Singh, R.K. Sagar, I.P. Kumar and A.K. Sinha, 2002. Radioprotection by herbal preparation of Hippophae rhamnoides, RH-3, against whole body lethal irradiation in mice. Phytomedicine, 9: 15-25.
  52. Yang, B., K.O. Kalimo, R.L. Tahvonen, L.M. Mattila, J.K Katajisto and H.P. Kallio, 2000. Effect of dietary supplementation with sea buckthorn (Hippophae rhamnoides) seed and pulp oils on the fatty acid composition of skin glycerophospholipids of patients with atopic dermatitis. J. Nutr. Biochem., 11: 338-340.
  53. Yang, B., K. Kalimo, L. Mattila, S. Kallio, J. Katajisto, O. Peltola and H. Kallio, 1999. Effect of dietary supplementation with sea buckthorn (Hippophae rhamnoides) seed and pulp oils on atopic dermatitis. J. Nutr. Biochem., 10: 622-630.
  54. Mingyu, X., X. Sun and W. Tong, 1994. Medical research and development on sea buckthorn. Hippophae, 7: 32-39.
  55. Suryakumar, G., M. Sai Ram, V. Singh, G. Ilavazhagan and R.C. Sawhney, 2002. Anti-oxidant and immunomodulatory properties of sea buckthorn (Hippophae rhamnoides). An in vitro study. J. Ethnopharmacol., 79: 373-378.
    CrossRefDirect Link
  56. Yang, B. and H. Kallio, 2002. Composition and physiological effects of sea buckthorn (Hippophae) lipids. Trends Food Sci. Technol., 13: 160-167.
  57. Yaonian, Q., B. Zhou, J. Li, Y. Bao and Y. Xue, 1999. Report on biochemical components of different type of sea buckthorn. Hippophae, 9: 32-36.
  58. Pengyuan, Z. and J. Jiang, 1992. Health benefits from sea buckthorn. Hippophae, 5: 20-25.
  59. Yao, Z., Y. Ye and M. Su, 1989. Some thoughts on standards of sea buckthorn for medical applications. Hippophae, 4: 41-43.
  60. Bernath, J. and D. Foldesi, 1992. Sea buckthorn (Hippophae rhamnoides L.): A promising new medicinal and food crop. J. Herbs Spices Med. Plants, 1: 27-35.
  61. Yang, B., H. Kallio, K. Kalimo, L. Mattila, S. Kallio, R. Tahvonen and J. Katajisto, 1999. Effects of dietary supplementation of sea buckthorn (Hippophae rhamnoides) oils on fatty acids in patients with atopic dermatitis. J. Nutr. Biochem., 10: 622-630.
    PubMed
  62. Zhou, Y., 1998. Study on the effect of Hippophae seed oil against gastric ulcer. Institute of Medical Plants Resource Development, The Chinese Academy of Medical Sciences, Beijing, China.
  63. Chai, Q., G. Xiayan, M. Zhao, H. Wemmin and Y. Giang, 1989. The experimental studies on the cardiovascular pharmacology of sea buckthorn extract from Hippophae rhamnoides L. Proceedings of the International Symposium, Sea Buckthorn Xina, (ISSBX`89), China, pp: 392-397.
  64. Yang, B. and H. Kallio, 2002. Supercritical CO2-extracted sea buckthorn (Hippophae rhamnoides) oils as new food ingredients for cardiovascular health. Proceedings of the Health Ingred Europe, September 17-19, 2002, Paris, France, pp: 7.
  65. Suleyman, H., F. Gocer, G. Ozbakis, D. Sadeler, M.E. Buyukokuroglu and N. Banoglu, 1997. The effect of oil extract of Hippophae rhamnoides L. on stress-induced gastric ulcer in rats. Proceedings of the 14th National Congress of Pharmacology, Nov. 2-7, Tekiova, Antalya, Turkey.
  66. Yang, B., H.P. Kallio, K.O. Kalimo, L.M. Mattila, R.L. Tahvonen, S.E. Kallio and J.K. Katajisto, 1999. Effects of Dietary Supplementation with Sea Buckthorn Seed and Pulp Oils on Fatty Acid Composition of Plasma Lipids in Patients with Atopic Dermatitis and Measurement of Skin Surface Roughness. In: Functional Foods-A New Challenge for the Food Chemists, Lasztity, R., W. Pfannhauser, L. Simon-Sarkadi and S. Tomoskozi (Eds.). TUB Publishing Company, Budapest, Hungary, pp: 124-131.
  67. Yang, B. and H. Kallio, 2003. Effect of sea Buckthorn oil (Hippophae rhamnoides) on skin: Eastern tradition and modern research. November 2003, Personal Care, pp: 46-49.
  68. Kallio, H., B.R. Yang, R. Tahvonen and M. Hakala, 1999. Composition of sea buckthorn berries of various origins. Proceeding of International Symposium on Sea Buckthorn (IWS) Beijing, China.
  69. Zhang, W., J. Yan, J. Duo, B. Ren and J. Guo, 1989. Preliminary study of biochemical constitutes of berry of sea buckthorn growing in Shanxi Province and their changing trend. Proceedings of the International Symposium on Sea Buckthorn (H. rhamnoides L.), Xian, China.

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