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First Report on the Identification of Nodularin from King Talal Reservoir (Jordan)

S. Al-Jassabi and A.M. Khalil

The aim of present study was to investigate Nodularia spumigena blooms intensity and their toxin concentration and biochemical characters in King Talal Reservoir. The time of the seasonal maximum intensity of this type of cyanobacterial blooms vary significantly from month to month during 2003. The maximum intensity of the bloom was from 30th of July-30th of Aug. The LD50 of nodularin in Balb/C mice was 44 μg kg-1 body weight (b.w.) and the maximum concentrations of nodularin in King Talal Reservoir water were 0.455 μg L-1 on 30th of July, 0.46 μg L-1 on 1st Aug and 0.45 μg L-1 on 30th of Aug. Therefore, it is considered as a potent biotoxin. By using NMR, it has shown that the structure of this peptide is similar to that found by others in other places of the world and biochemical studies on this toxin showed that more than 50% inhibition of PP1 occurred at these concentrations.

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  How to cite this article:

S. Al-Jassabi and A.M. Khalil , 2004. First Report on the Identification of Nodularin from King Talal Reservoir (Jordan). Journal of Biological Sciences, 4: 559-563.

DOI: 10.3923/jbs.2004.559.563


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