An experimental study was conducted to investigate the effects induced in broiler chickens by excess sodium from different compounds, namely sodium chloride (SC), sodium bicarbonate (SB) and sodium phosphate (SP), added to the drinking water. Higher and lower doses of the these compounds were administered to the treated birds. All the high-dosed birds died during the first 10 days post-treatment. Histological examination revealed significant myocardial alterations in all groups, however these were more pronounced in the SC-group while SB-and SP-groups showed marked renal changes. Erythrocyte deformability was decreased in all treated birds and probably was related to the increased mean corpuscular volume (MCV) of erythrocytes.
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Muhammad Mubarak, 2004. Histopathology of Toxicity Induced in Broiler Chickens by Excess Sodium Compounds. Journal of Biological Sciences, 4: 553-558.