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In vitro Studies of Antimicrobial Activity of Synthetic Ovaliflavone

Sayed Alam , M.A. Jalil Miah and Azizul Islam

In the present study 8-γ,γ-dimethyallyl-5, 7-dimethoxyflavone [ovaliflavone, 6] has been synthesized from phloroacetophenone via chalcone precursor and by its treatment with DMSO/I2 or diphenyl sulphide. The antibacterial and antifungal activities of ovaliflavone and its corresponding chalcone were found in vitro by the filter paper disc diffusion method and poisoned food technique, respectively. Compound 6 showed good antibacterial and antifungal activities to the some selected bacterial and fungal strain.

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  How to cite this article:

Sayed Alam , M.A. Jalil Miah and Azizul Islam , 2004. In vitro Studies of Antimicrobial Activity of Synthetic Ovaliflavone. Journal of Biological Sciences, 4: 527-531.

DOI: 10.3923/jbs.2004.527.531


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