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Journal of Biological Sciences

Year: 2001 | Volume: 1 | Issue: 8 | Page No.: 761-764
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Research Article

Plasma Free Amino Acids Levels in Rats with Parasitically Infected Liver

Nasreen Gill, M.Saleh Memon and M. Munif Khan

ABSTRACT

Amino acid variation in different organs of rats Rettus norvegicus collected from different areas of Sindh for parasitic and biochemical analysis. Chromatographic separation of free amino acids, in normal and infected rats with endoparasites, using two different solvent system for avoiding overlapping have been used. The amino acid variation have been observed in liver (cyst) infection, liver (cyst) with intestine single (cestode) infection, liver (cyst) with intestine double (cestode +nematode) infection, liver (cyst) with blood single or both (sporozoan + trypanosome) infection, liver (cyst) with intestine (cestode) and blood (sporozoan or trypanosome) infection, liver (cyst) with intestine (nematode) infection. Isoleucine was totally absent in all types of infections. In liver (cyst) and blood (trypanosome and sporozoan) with double infection, only histidine was present in the plasma of the infected rats while all other amino acid which are normally present were totally absent. Leucine, methionine and valine were mostly absent except in some rats, infected with all type of endoparasitic infections.
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