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Research Article
 

Optimizations of Conditions for Maximum Recovery of Astragalin from Thesium chinense Turcz



Zahida Parveen , Yulin Deng , Muhammad Khalid Saeed , Rongji Dai , Waqar Ahmad , Yuhong Yu and Tahmina Yasmeen
 
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ABSTRACT

Astragalin, one of the flavonoid extracted from plants is increasingly in demand in food and pharmaceutical industries due to its various biological and physiological activities including antioxidation, antiallergy, anti-inflammation and anti-hepatoptoxic. The whole plant of Thesium chinense Turcz is a major source of astragalin. This study developed a low-cost process encompassing the efficient extraction, fractionation, isolation and recrystallization to obtain high-purity astragalin from Thesium chinense and it could improve the economic utilization of this plant. In this study plant was extracted with 80% ethanol for 3 h and extract was fractionated on AB-8 (styrene based copolymer) with water, 20, 40 and 80% aqueous ethanol. Astragalin was isolated by silica gel column and purified by recrystalization with methanol. These conditions resulted 90% recovery of Astragalin with 95% purity.

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  How to cite this article:

Zahida Parveen , Yulin Deng , Muhammad Khalid Saeed , Rongji Dai , Waqar Ahmad , Yuhong Yu and Tahmina Yasmeen , 2006. Optimizations of Conditions for Maximum Recovery of Astragalin from Thesium chinense Turcz. Journal of Applied Sciences, 6: 2829-2832.

DOI: 10.3923/jas.2006.2829.2832

URL: https://scialert.net/abstract/?doi=jas.2006.2829.2832

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