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Avian Salmonellosis and Colibacillosis: Risk Factors, Antibiotic Resistance, Public Health Impact and Biological Control



O.N.C. Aguidissou, Y. Akpo, A.M.J. Adoko, C.M. Adoligbé, B.G. Koutinhouin, C.K. Boko and S. Farougou
 
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ABSTRACT

Salmonella spp. and Escherichia coli are the two leading causes of foodborne bacterial zoonosis in the world. Respectively responsible for avian pullorosis/typhosis and colibacillosis in poultry, these pathogens represent major constraints for the poultry industry (layers, broilers) in the world because of the mortality and economic losses generated. The isolation of multidrug resistant Salmonella and E. coli strains in poultry farms in several parts of the world reflects the global aspect of the problem. Antibiotics are essential in the treatment and control of these two bacterial diseases. Resistance results in the progressive ineffectiveness of several families of antibiotics, which constitutes a threat to animal health, food safety and public health. This article reviews the various studies conducted on avian salmonellosis and colibacillosis. The antibiotic molecules to which Salmonella spp. and Escherichia coli strains are resistant are discussed. The virulence and resistance genes associated with the different serotypes are reported. Finally, the risk factors, the impact on public health and some pyhtotherapeutic solutions are described. A better knowledge of this information will allow the poultry industry to make further progress in the elimination of salmonellosis and avian colibacillosis, the reduction of antibiotic use and the potential public health risks.

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  How to cite this article:

O.N.C. Aguidissou, Y. Akpo, A.M.J. Adoko, C.M. Adoligbé, B.G. Koutinhouin, C.K. Boko and S. Farougou, 2022. Avian Salmonellosis and Colibacillosis: Risk Factors, Antibiotic Resistance, Public Health Impact and Biological Control. International Journal of Poultry Science, 21: 90-106.

DOI: 10.3923/ijps.2022.90.106

URL: https://scialert.net/abstract/?doi=ijps.2022.90.106
 
Copyright: © 2022. This is an open access article distributed under the terms of the creative commons attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.

 INTRODUCTION

Poultry farming is one of the most important sources of animal protein and income in the world in general and particularly in Africa1. It is a sub-sector that contributes considerably to the economy of several African countries and thus play key role in fighting against hunger and poverty. Despite of its importance, this sub-sector is facing major disease challenges that hinder the agricultural and socio-economic development of many countries. Among these, salmonellosis and colibacillosis are the main bacterial diseases caused by Salmonella spp. and Escherichia coli respectively and are considered as one of the main causes of morbidity and mortality either as a primary or secondary pathogen2. In West Africa, salmonellosis alone causes significant economic losses with mortalities of up to 90%3. Antibiotic therapy with synthetic molecules is one of the ways to control these diseases. These molecules are used either for curative or preventive purposes, or as growth promoters in feed4. Their use in poultry farming has undoubtedly improved the productivity5. However, the frequent and uncontrolled use of these molecules has progressively contributed to the emergence of resistant bacteria, in this case Salmonella and Escherichia coli strains that are multi-resistant to different families of antibiotics6. According to Chang et al.7; Economou and Gousia8, the use of antibiotics in veterinary medicine and farm animals is of constant concern because of the possible transmission of resistant bacteria to human through food consumption and environment. New effective and accessible treatment methods must therefore be envisaged to reduce the speed at which this microbial resistance develops. Medicinal plants, through their pharmacological effects, are an option to be considered. Used for thousands of years, they represent a significant source of new drugs. The abundance of research work in this area confirms the renewed interest in their use in the treatment of animals9. In Benin, the poultry sub-sector is booming but bacterial resistance related to Salmonella and Escherichia coli is one of the major challenges for it. The objective of this article is to: (1) Synthesize recent information on the different serotypes isolated and their associated virulence genes, (2) Determine the bacterial resistance to antibiotics and and their impact on public health (3) Review some phytosanitary treatments performed against these bacteria in several regions of the world.

Avian salmonellosis and colibacillosis

Avian salmonellosis: Avian salmonellosis is one of the most common bacterial infections of poultry. It is caused by the multiplication in the body of germs of the Salmonella genus, a facultative intracellular pathogenic bacterium causing local or systemic infections and belonging to the Enterobacteriaceae family10. The genus Salmonella currently includes 2659 serovars belonging to two species: Salmonella enterica which has 6 subspecies (enterica, salamae, arizonae, diarizonae, houtenae, indica) and Salmonella bongori. Of these many serovars, only 10% have been isolated from poultry and over 50% from humans2. In poultry farming, there are two types of infection due to Salmonella Pullorum and Salmonella Gallinarum are the etiological agents of pullorosis and avian typhosis, respectively, which cause huge economic losses to the poultry industry. Besides the serovar Gallinarum/Pullorum recognized as specific to poultry, there are other serovars (Salmonella enteritidis, S. Typhimurium, S. Hadar, S. Heidelberg, S. Saintpaul and S. Infantis) less or non-specific, also responsible for the development of poultry infections and moreover, involved mainly in the public health problem via the consumption of food of animal origin11. Two types of transmission are possible in poultry farms: vertical and horizontal transmission. Vertical transmission can be transovarial (direct contamination of the egg during its formation from the infected ovary or oviduct)12. Horizontal transmission, on the other hand, occurs orally, through contact with virulent materials (feces), the environment as well as water and food. It can infect chicks, pullets as well as adult hens. Thus, several Salmonella serotypes have been isolated from poultry farms, their environments, poultry carcasses and also table eggs13,14. Apart from the different Salmonella serotypes isolated till date, different virulence genes associated with them have also been determined by PCR technique from DNA and also plasmid analysis. Table 1 summarizes the recently identified Salmonella serovars and their associated virulence genes.