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Research Article
 

Effect of Spirulina on Biochemical Parameters and Reduction of Tissue Arsenic Concentration in Arsenic Induced Toxicities in Ducks



M.S. Islam, M.A. Awal, M. Mostofa, F. Begum, A. Khair and M. Myenuddin
 
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ABSTRACT

The present study was undertaken for the effect of spirulina on biochemical parameters and reduction of tissue arsenic concentration in arsenic induced toxicities in ducks. One hundred and seventy 5 ducklings were divided into five equal groups separately. One group (T0) of ducklings was kept as control. One group (T1) of ducklings were given arsenic trioxide @ 100 mg/L drinking water and rest three groups of ducklings (T2, T3 and T4) were given arsenic trioxide @ 100 mg/L plus spirulina in three different doses i.e. 30, 60 and 120 mg/L in drinking water daily for 90 days starting from day 15. Five birds were sacrificed from each group in every 15 day intervals and biochemical parameters were determined. All the biochemical parameters (SGPT, SGOT, ALP, LDH and ACP) were significantly (p<0.01) elevated in arsenic treated groups. However, the elevation of these parameters was less in arsenic plus spirulina treated groups (T2, T3 and T4). The distribution of arsenic concentration was highest in liver and lowest in faeces. Maximum reduction of arsenic was recorded in all organs following highest doses of spirulina (120 mg/L). The present study reveals that spirulina may be helpful for reducing the tissue burden of arsenic in ducks.

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  How to cite this article:

M.S. Islam, M.A. Awal, M. Mostofa, F. Begum, A. Khair and M. Myenuddin, 2009. Effect of Spirulina on Biochemical Parameters and Reduction of Tissue Arsenic Concentration in Arsenic Induced Toxicities in Ducks. International Journal of Poultry Science, 8: 69-74.

DOI: 10.3923/ijps.2009.69.74

URL: https://scialert.net/abstract/?doi=ijps.2009.69.74

REFERENCES

1:  Ahmed, S., 2004. Effect of filtration of arsenic contaminated water and interaction of arsenic with few reagents in rabbit (Orictolagus cunculus). M.Sc. Thesis, Department of Pharmacology, Bangladesh Agricultural University, Mymensingh, Bangladesh.

2:  Alam, T., 2004. The role of ascorbic acid, alpha-tocopherol and ferrous sulphate on arsenic induced toxicity in long evans rats. M.Sc. Thesis, Department of Pharmacology, Bangladesh Agricultural University, Mymensingh, Bangladesh.

3:  Bednar, A.J., J.R. Garbarino, I. Ferrer, D.W. Rutherford, R.L. Wershaw, J.F. Ranville and T.R. Wildeman, 2003. Photodegradation of roxarsone in poultry litter leachates. Sci. Total Environ., 302: 237-245.
CrossRef  |  

4:  Chiou, P.W.S., K.L. Chen and B. Yu, 1997. Effects of roxarsone on performance, toxicity, tissue accumulation and residue of eggs and excreta in laying hens. J. Sci. Food Agric., 74: 229-236.
CrossRef  |  Direct Link  |  

5:  Deneke, U. and W. Rittersdorf, 1984. Evaluation of the refloquant GPT (ALT) reagent carriers with reflotron. Clin. Chem., 30: 1009-1009.

6:  Deneke, U., W. Rittersdorf and W. Werner, 1985. Performance data of Reflotron-GOT (AST) dry chemistry test for reflotron. Clin. Chem., 31: 921-921.

7:  Dinman, B.D., E.A. Hamdi, C.F. Fox and W.J. Frajola, 1963. CC14 Toxicity. III. Hepatostructural and enzymatic changes. Arch. Environ. Health, 7: 630-646.
PubMed  |  Direct Link  |  

8:  Drotman, R.B. and G.T. Lawhorn, 1978. Serum enzymes as indicators of chemically induced liver damage. Drug Chem. Toxicol., 1: 163-171.
CrossRef  |  PubMed  |  Direct Link  |  

9:  EPA, 1980. Ambient water quality criteria for arsenic 1980. US Environ. Protection Agency Report, pp: 205.

10:  Department of National Health and Welfare and the Canadian Association of Occupational Therapists, 1983. Guidelines for the client-centred practice of occupational therapy (H39-33/1983E). Department of National Health and Welfare, Ottawa, ON.

11:  Gartrell, M.J., J.C. Craun, D.S. Podrebarac and E.L. Gunderson, 1986. Pesticides, selected elements and other chemicals in adult total diet samples, October 1980 to March 1982. J. Assoc. Official Anal. Chem., 69: 146-159.
PubMed  |  Direct Link  |  

12:  Islam, A.K.M.S., M.A. Awal, A.S.M. Bari, M.M. Rahman, S. Begum and M.S. Islam, 2001. Effects of experimentally induced toxicosis with arsenic trioxide on body weight in different organs in mice. Bangladesh Vet. J., 35: 151-153.

13:  Islam, M.N., M.A. Awal, M.M. Rahman, M.S. Islam and M. Mostofa, 2005. Effects of arsenic alone and in combination with selenium, iron and zinc on clinical signs, body weight and hematobiochemical parameters in long evans rats. Bangladesh J. Vet. Med., 3: 75-77.

14:  Lasky, T., W. Sun, A. Kadry and M.K. Hoffman, 2004. Mean total arsenic concentrations in chicken 1989-2000 and estimated exposures for consumers of chicken. Environ. Health Perspect., 112: 18-21.
Direct Link  |  

15:  Misbahuddin, M., A.Z.M.M. Islam, S. Khandker and N. Islam, 2006. Efficacy of Spirulina extract plus zinc in patients of chronic arsenic poisoning: A randomized placebo-controlled study. Clin. Toxicol., 44: 135-147.
Direct Link  |  

16:  Olayemi, F.O., R.O.A. Arowlo, A.B. Saba and S.A. Fankinde, 2002. Effect of sex on the blood profile of the Nigerian duck. Bull. Anim. Health Prod. Afr., 50: 67-71.

17:  Peto, R., R. Doll, J.D. Buckley and M.B. Sporn, 1981. Can dietary beta-carotene materially reduce human cancer rates? Nature, 290: 201-208.
CrossRef  |  Direct Link  |  

18:  Pizzaro, I., M.M. Gomez, P. Fodor, M.A. Palacios and C. Camara, 2004. Distribution and biotransformation of arsenic species in chicken cardiac and muscle tissues. Biol. Trace Element Res., 99: 129-143.
CrossRef  |  Direct Link  |  

19:  Robert, H., 1989. Earth Food Spirulina. Ronor Enterprises Inc., Laguna Beach, California, USA

20:  Ramazzotto, P. and R. Carlin, 1978. Effects of DMSO on SGOT during hypothermia in adrenalectomized rats. Life Sci., 22: 329-336.
PubMed  |  Direct Link  |  

21:  Sharma, A., M.K. Sharma and M. Kumar, 2007. Protective effect of Mentha piperita against arsenic-induced toxicity in liver of Swiss albino mice. Basic Clin. Pharmacol. Toxicol., 100: 249-257.
CrossRef  |  Direct Link  |  

22:  Shekelle, R.B., W.J. Raynor and M. Lepper, 1981. Dietary vitamin A and risk of cancer in the Western electric study. Lancet, 8257: 1185-1189.
PubMed  |  Direct Link  |  

23:  Taggart, M.A., J. Figuerola, A.J. Green, R. Mateo, C. Deacon, D. Osborn and A.A. Meharg, 2006. After the aznalcollar mine spill: Arsenic, zinc, selenium, lead and copper levels in the livers and bones of five waterfowl species. Environ. Res., 100: 349-361.
Direct Link  |  

24:  Tao, S.S. and P.M. Bolger, 1999. Dietary arsenic intakes in the United States: FDA total diet study, September 1991 to December 1996. Food Additives Contam., 16: 465-472.
CrossRef  |  Direct Link  |  

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