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International Journal of Poultry Science

Year: 2009 | Volume: 8 | Issue: 6 | Page No.: 583-587
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Research Article

Effects of Different Sources and Levels of Selenium on Performance, Thyroid Function and Antioxidant Status in Stressed Broiler Chickens

Chun Fan, Bing Yu and Daiwen Chen

ABSTRACT

The effects of adding different sources and levels of selenium on performance, thyroid function and antioxidant status in stressed broiler chickens were evaluated. Stress was induced by supplementation with 20 mg/kg Corticosterone (CORT) in basal diet. Total 144 Avian broilers were used for 2 weeks from 14 days of age, which were randomly distributed to 6 groups. One of these groups was fed with basal diets and the remaining with basal diet supplemented with CORT. Meanwhile, diets used in CORT groups were supplemented with 0, 0.1 or 0.4 mg/kg sodium selenite or yeast selenium, respectively. The results showed that dietary CORT resulted in significant suppression of growth and thyroid function, increase in creatine kinase activity and uric acid concentration in serum, indicating that CORT induced stress of broilers. In addition, the balance between pro-oxidants and antioxidants was disturbed by CORT administration, resulting in oxidative injury in the body. Supplementation of dietary selenium improved feed efficiency, promoted conversion of thyroxine (T4) to triiodothyronine (T3), minimized the changes of blood biochemical parameters; furthermore, it elevated antioxidases activities and decreased lipid peroxidation products in stressed broilers. The effects of adding 0.4 mg/kg selenium were better than 0.1 mg/kg. Although there was no significant difference between two selenium sources, it was conclude that high level of inorganic or organic selenium was able to attenuate stress and oxidative injury due to exogenous CORT administration, especially organic yeast selenium.
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REFERENCES

  1. Arthur, J.R., F. Nicol and G.J. Beckett, 1990. Hepatic iodothyronine 5'2-deiodinase: The role of selenium. Biochem. J., 272: 537-542.
  2. Darras, V.M., S.P. Kotanen, K.L. Geris, L.R. Berghman and E.R. Kuhn, 1996. Plasma thyroid hormone levels and iodothyronine deiodinase activity following an acute glucocorticoid challenge in embryonic compared with posthatch chickens. Gen. Comp. Endocrinol., 104: 203-212.
    CrossRef
  3. Eid, Y.Z., A. Ohtsuka and K. Hayashi, 2003. Tea polyphenols reduce glucocorticoids induced growth inhibition and oxidative stress in broiler chickens. Br. Poult. Sci., 44: 127-132.
    PubMed
  4. Ekholm, R. and U. Bjorkman, 1997. Glutathione peroxidase degrades intracellular hydrogen peroxide and thereby inhibits intracellular protein iodination in thyroid epithelium. Endo, 138: 2871-2878.
    PubMed
  5. Jianhua, H., A. Ohtsuka and K. Hayashi, 2000. Selenium influences growth via thyroid hormone status in broiler chickens. Br. J. Nutr., 84: 727-732.
    Direct Link
  6. Jiang, K.J., 2007. Effects of stress and dietary energy level on growth and lipid metabolism of broiler chickens. M.A. Thesis, Shandong Agricaltual University, Tai'an, China.
  7. Lin, H., E. Decuypere and J. Buyse, 2004. Oxidative stress induced by corticosterone administration in broiler chickens (Gallus gallus domesticus): 1. Chronic exposure. Comp. Biochem. Physiol. Part B: Biochem. Mol. Biol., 139: 737-744.
    CrossRefDirect Link
  8. Malherios, R.D., V.M. Moraes, A. Collin, E. Decuypere and J. Buyse, 2003. Free diet selection by broiler as influenced by dietary macronutrient ratio and corticosterone supplementation.1. Diet selection, organ weights and plasma metabolites. Poult. Sci., 82: 123-131.
    Direct Link
  9. Moberg, G.P. and J.A. Mench, 2000. The Biology of Animal Stress: Basic Princilies and Implications for Animal Welfare. CABI Publishing, UK., pp: 3-6.
  10. NRC., 1994. Nutrient Requirements of Poultry. 9th Edn., National Academy Press, Washington, DC., USA., ISBN-13: 9780309048927, Pages: 155.
    Direct Link
  11. Ohtsuka, A., T. Ohtani, H. Horiguchi and K. Hayashi, 1998. Vitamin E reduces glucocorticoids induced growth inhibition and lipid peroxidation in rats. J. Nutr. Sci. Vitaminol., 44: 237-247.
    PubMed
  12. Sui, S.J., 2005. Effects of stress and energy type of diets on meat quality of broilers. M.A. Thesis, Shandong Agricaltual University, Tai'an, China.
  13. Taniguchi, N., A. Ohtsuka and K. Hayashi, 1999. Effect of dietary corticosterone and vitamin E on growth and oxidative stress in broiler chickens. Anim. Sci. J., 7: 195-200.
  14. Virden, W.S., M.S. Lilburn, J.P. Thaxton, A. Corzo, D. Hoehler and M.T. Kidd, 2007. The effect of corticosterone induced stress on amino acid digestibility in Ross broiler. Poult. Sci., 86: 338-342.
    Direct Link
  15. Watanabe, C., C.Y. Kima and H. Satoha, 1997. Tissue-specific modification of selenium concentration by acute and chronic dexamethasone administration in mice. Br. J. Nutr., 78: 501-509.
    Direct Link
  16. Yuan, S.B., 2007. Impacts of oxidative stress on piglets and the anti-stress effect and mechanism of selenium. Ph.D. Thesis, Sichuan Agricaltual University, Yaan, China.

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