Subscribe Now Subscribe Today
Research Article
 

The Effects of Direct-fed Microbial, Primalac®, or Salinomycin Supplementation on Intestinal Lactate Isomers and Cecal Volatile Fatty Acid Concentrations in Broilers1



J. Croom, M. Chichlowski, M. Froetschel, B.W. McBride, R. Qui and M.D. Koci
 
Facebook Twitter Digg Reddit Linkedin StumbleUpon E-mail
ABSTRACT

Direct-Fed Microbials (DFM) are a putative alternative to the feeding of sub-therapeutic levels of antibiotics in the production of poultry and other livestock species. This study was designed to examine the effects of a commercial DFM (Primalac®), or salinomycin (SAL), a commonly used antibiotic and coccidiostat supplement, on fermentation patterns and lactate production in the cecum and the lower intestinal tract of broiler chickens. L-lactate and total lactate concentrations in the digesta fluid of the ileum decreased (P<0.01) with the DFM feeding in comparison to CON and SAL treatments while d-lactate concentration increased (P<0.04) in comparison to CON. Total cecal VFA concentration was lower (P<0.003) with DFM feeding and SAL than the CON. In the present study both dietary supplements, DFM and SAL, altered lactic acid and VFA concentrations in the cecum and intestines of experimental animals; however the full spectrum of mechanisms responsible for antibacterial properties and growth promotion associated with those changes remains to be elucidated.

Services
Related Articles in ASCI
Search in Google Scholar
View Citation
Report Citation

 
  How to cite this article:

J. Croom, M. Chichlowski, M. Froetschel, B.W. McBride, R. Qui and M.D. Koci, 2009. The Effects of Direct-fed Microbial, Primalac®, or Salinomycin Supplementation on Intestinal Lactate Isomers and Cecal Volatile Fatty Acid Concentrations in Broilers1. International Journal of Poultry Science, 8: 128-132.

DOI: 10.3923/ijps.2009.128.132

URL: https://scialert.net/abstract/?doi=ijps.2009.128.132

REFERENCES

1:  Bjerrum, L., R.M. Engberg, T.D. Leser, B.B. Jensen, K. Finster and K. Pedersen, 2006. Microbial community composition of the ileum and cecum of broiler chickens as revealed by molecular and culture based techniques. Poult. Sci., 85: 1151-1164.
PubMed  |  Direct Link  |  

2:  Bagley, C.P., J.I. Feazel, D.G. Morrison and D.M. Lucas, 1988. Effects of salinomycin on ruminal characteristics and performance of grazing beef steers. J. Anim. Sci., 66: 792-797.

3:  Chichlowski, M., J. Croom, B.W. McBride, L. Daniel, G. Davis and M.D. Koci, 2007. Direct-fed Microbial primalac and salinomycin modulate whole-body and intestinal oxygen consumption and intestinal mucosal cytokine production in the broiler chick. Poult. Sci., 86: 1100-1106.
CrossRef  |  PubMed  |  Direct Link  |  

4:  Davis, G.S. and K.E. Anderson, 2002. The effects of feeding the direct-fed microbial, primalac, on growth parameters and egg production in single comb white leghorn hens. Poult. Sci., 81: 755-759.
CrossRef  |  PubMed  |  Direct Link  |  

5:  Engberg, R.M., M.S. Hedemann, T.D. Leser and B.B. Jensen, 2000. Effects of zinc bacitracin and salinomycin on intestinal microflora and performance of broilers. Poult. Sci., 79: 1311-1319.
PubMed  |  Direct Link  |  

6:  Garcia, C.K., J.L. Goldstein, R.K. Pathak, R.G.W. Anderson and R.M.S. Brown, 1964. Molecular characterization of a membrane transporter for lactate, pyruvate and other monocarboxylates: Implications for the Cori cycle. Cell, 76: 865-873.
Direct Link  |  

7:  Jin, L.Z., Y.W. Ho, N. Abdullah, M.A. Ali and S. Jalaludin, 1998. Effect of adherent Lactobacillus cultures on growth, weight of organs and intestinal microflora and volatile fatty acids in broilers. Anim. Feed Sci. Technol., 70: 197-209.

8:  Marounek, M., V. Rada and V. Benda, 1996. Effect of ionophores and 2-bromoethanesulphonic acid in hen caecal methanogenic cultures. J. Anim. Feed Sci., 5: 425-425.

9:  Marounek, M., O. Suchorska and O. Savka, 1999. Effect of substrate and feed antibiotics on in vitro production of volatile fatty acids and methane in caecal contents of chickens. Anim. Feed Sci. Technol., 80: 223-230.

10:  Mirdamadi, S., H. Sadeghi, N. Sharafi, M. Fallahpour, F.A. Mohseni and M.R. Bakhtiari, 2002. Comparison of lactic acid isomers produced by fungal and bacterial strains. Iran Biomed. J., 6: 69-75.

11:  Mountzouris, K.C., P. Tsirtsikos, E. Kalamara, S. Nitsch, G. Schatzmayr and K. Fegeros, 2007. Evaluation of the efficacy of a probiotic containing Lactobacillus, Bifidobacterium, Enterococcus and Pediococcus strains in promoting broiler performance and modulating cecal microflora composition and metabolic activities. Poult. Sci., 86: 309-317.
CrossRef  |  PubMed  |  Direct Link  |  

12:  Nemcova, R., 1997. Criteria for selection of lactobacilli for probiotic use. Vet. Med. (Praha), 42: 19-27.
Direct Link  |  

13:  Patterson, J.A. and K.M. Burkholder, 2003. Application of Prebiotics and Probiotics in poultry production. Poult. Sci., 82: 627-631.
Direct Link  |  

14:  Spears, J.W., 1990. Ionophores and nutrient digestion and absorption in ruminants. J. Nutr., 120: 632-638.
PubMed  |  Direct Link  |  

15:  Taylor, R., 2002. Hindgut function in the laying hen. A Report for the Rural Industries Research and Development Corporation. Publication No. 02/043, Newcastle, Australia.

16:  Wang, Z.R., S.Y. Oiao, W.O. Lu and D.F. Li, 2005. Effects of enzyme supplementation on performance, nutrient digestibility, gastrointestinal morphology and volatile fatty acid profiles in the hindgut of broilers fed wheat-based diets. Poult. Sci., 84: 875-881.
CrossRef  |  Direct Link  |  

17:  Zhang, W.F., D.F. Li, W.Q. Lu and G.F. Yi, 2003. Effects of isomalto-oligosaccharides on broiler performance and intestinal microflora. Poult. Sci., 82: 657-663.
CrossRef  |  PubMed  |  Direct Link  |  

©  2021 Science Alert. All Rights Reserved