Antimicrobial agent resistance has been recognized as an
emerging worldwide problem in both human and animals, antimicrobial agent
use is considered the most important factor for the emergence, selection
and dissemination of antimicrobial agent-resistant bacteria, intrinsically
either acquires the resistance gene from other bacterial environment or
development of pumping out mechanism. The aim of this study was to
generate baseline data on the prevalence of antimicrobial resistance in
Escherichia coli isolates from different sources. Seventy E.
coli isolates from humans and environments were tested for
susceptibility to 10 antimicrobial agents by diffusion method. Resistance
was found in 61.2% of the isolates. The most prevalent resistances were to
kanamycin and tetracycline (81.4%), followed by chloramphenicol (75.7%)
and gentamicin, (74.3%). The low prevalent were to cefetoxin (44.3%),
norofluoxacin (27.1%) and ciprofluoxacin (24.3%). This study showed the
distribution of antimicrobial agent resistance in E. coli isolates
from a variety of sources and analysis of such patterns of resistance may
prove to be useful beyond simple description. Regarding to the concern of
water quality and environmental contamination by human and agricultural
waster have increased, it has become increasingly important to develop
low-cost screening tools that can be used to identify the most probable
source of contamination.
N. Alhaj, N.S. Mariana, A.R. Raha and Z. Ishak, 2007. Prevalence of Antibiotic Resistance among Escherichia coli from Different Sources in Malaysia. International Journal of Poultry Science, 6: 293-297.