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Research Article
 

16 α Hydroxy-(-)-kauran-19-oic Acid: An Antibacterial Diterpene from Sweet Apple (Annona squamosa L., Annonaceae)



Christophe Wiart , Ta Siang Au , Yusof Mohd , Hassan Hamimah and Mazdida Sulaiman
 
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ABSTRACT

The methanolic extract of sweet apple (Annona squamosa L.) showed a good antibacterial activity against both ATCC and clinical strains of Staphylococcus aureus and Streptococcus pneumoniae. 16 α Hydroxy-(-)-kauran-19-oic acid, was identified as the compound responsible for the antibacterial activity of this plant.

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  How to cite this article:

Christophe Wiart , Ta Siang Au , Yusof Mohd , Hassan Hamimah and Mazdida Sulaiman , 2005. 16 α Hydroxy-(-)-kauran-19-oic Acid: An Antibacterial Diterpene from Sweet Apple (Annona squamosa L., Annonaceae). International Journal of Pharmacology, 1: 296-298.

DOI: 10.3923/ijp.2005.296.298

URL: https://scialert.net/abstract/?doi=ijp.2005.296.298

REFERENCES

1:  Kirtikar, K.R. and B.D. Basu, 1980. Indian Medicinal Plants. 2nd Edn., Bishen Singh Mahendra Pal Sing, India

2:  Li, X.H., Y.H. Hui, J.K. Rupprecht, Y.M. Liu and K.V. Wood et al., 1990. Bullatacin, bullatacinone and aquaone, a new bioactive acetogenin from the bark of Annona squamosa. J. Nat. Prod., 53: 81-86.

3:  Wu, Y.C., Y.C. Hung, F.R. Chang, M. Consetino, H.K. Wang and K.H. Lee, 1996. Identification of ent-16 beta, 17 Bdihydroxykauran-19-oic acid as an anti-HIV principle and isolation of the new diterpenoids annosquamosin A and B from Annona squamosa. J. Nat. Prod., 59: 635-637.

4:  Wu, Y.C., F.R. Chang, S.T. Lu and S.K. Wang, 1994. Bioactive alkaloids from Annona squamosa. Chinese Pharm. J., 46: 438-446.

5:  Yang, X.J., L.Z. Xu, S.C. Wang and G. Zheng, 1992. Studies on the chemical constituents of Annona squamosa. Acta Pharm. Sinica, 27: 185-190.
PubMed  |  

6:  Bauer, A.W., W.M.M. Kirby, J.C. Sherris and M. Turck, 1966. Antibiotic susceptibility testing by a standardized single disk method. Am. J. Clin. Pathol., 45: 493-496.
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