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    Publisher: Asian Network for Scientific Information
   
  Research Journal of Mutagenesis is an international multi-disciplinary journal designed to bring together research aimed at the identification, characterization and elucidation of the mechanisms of action of physical, chemical and biological agents capable of producing genetic change in living organism and the study of the consequences of such changes. Scope of the journal includes: Fundamental and molecular mechanisms of mutagenesis, genetic toxicology and environmental mutagenesis, responses to DNA damage and other aspects of genomic stability.

  Editor-in-Chief:  Carlos Eduardo Fonseca Alves
 
 
Aguiar, A.C.S., M.M.P. Rodrigues, C.E. Fonseca-Alves, F.C.A. Santos, P.S.L. Vilamaior, S.R. Taboga and R. Laufer-Amorim, 2013. Female paraurethral prostate gland in bitches. Braz. J. Vet. Pathol., 6: 106-110.
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Alves, C.E.F., A.G. Correa, S.S. Costa and S.G. Calazans, 2013. Nodular dermatofibrosis in a German shepherd dog: case report. Pak. J. Biol. Sci., 16: 1623-1625.
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Alves, R.C.C., T.L. Batista, R. Laufer-Amorim, F. Elias, S.G. Calazans and C.E. Fonseca-Alves, 2015. Clinicopathological and immunohistochemical evaluation of oesophagealleiomyosarcoma in a dog. Ciencia Rural, (In Press). 10.1590/0103-8478cr20140686.
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Azevedo, E.M.R., S.C. Duarte, H.X. Costa, C.E. Fonseca-Alves, O.J. Silveira Neto, V.S. Jayme and G.F.C. Linhares, 2011. Linhares, Studies on canine visceral leishmaniasis in the municipality of Goiania, Goias, Brazil. J. Trop. Pathol., 40: 159-168.
Bersano, P.R.O., M.T. S. Alves, M.F.M.R. Gartner, A.C. Ferrasi and J.F. Lima-Neto et al., 2013. Role of selective cyclo-oxygenase-2 inhibitor celecoxib in canine osteosarcoma cell culture. Open J. Pathol., 3: 144-149.
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Branco, A., A.S. Rodrigues, A.T. Fabro, C.E. Fonseca-Alves and R.H.G. Martins, 2014. Hyaluronic acid behavior in the lamina propria of the larynx with advancing age. Otolaryngol. Head Neck Surg., 151: 652-656.
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Brandao, J.S., M.L. Alvarenga, J.P.H. Pfeifer, V.H. dos Santos and C.E. Fonseca-Alves et al., 2018. Allogeneic mesenchymal stem cell transplantation in healthy equine superficial digital flexor tendon: A study of the local inflammatory response. Res. Vet. Sci., 118: 423-430.
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Buzatto, A.B., F. Elias, M.S. Franzoni and C.E. Fonseca-Alves, 2019. Long-term survival of a cat with primary leiomyosarcoma of the urinary bladder. Vet. Sci., Vol. 6. 10.3390/vetsci6030060.
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Calazans, S.G., C.E.F. Alves, N.M. Zanetti, V.A. Conforti, J. Santilli, D.S. Anjos and G.M. Magalhaes, 2016. Metastatic kidney carcinoma causing paralysis of pelvic limbs in a dog. Pak. Vet. J., 36: 124-126.
Calderon, L.G.R., P.E. Kobayashi, R.O. Vasconcelos, C.E. Fonseca-Alves and R. Laufer-Amorim, 2019. Characterization of collagen fibers (I, III, IV) and elastin of normal and neoplastic canine prostatic tissues. Vet. Sci., Vol. 6. 10.3390/vetsci6010022.
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Costa, C.D., A.A. Justo, P.E. Kobayashi, M.M. Story, C. Palmieri, R.L. Amorim and C.E. Fonseca-Alves, 2019. Characterization of OCT3/4, Nestin, NANOG, CD44 and CD24 as stem cell markers in canine prostate cancer. Int. J. Biochem. Cell Biol., 108: 21-28.
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Da Silva, L., C.E. Fonseca‐Alves, J.J. Thompson, R.A. Foster, G.A. Wood, R.L. Amorim and B.L. Coomber, 2017. Pilot assessment of vascular endothelial growth factor receptors and trafficking pathways in recurrent and metastatic canine subcutaneous mast cell tumours. Vet. Med. Sci., 3: 146-155.
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De Nardi, A.B., M.T. Costa, R.L. Amorim, R.O. Vasconcelos and M.L. Dagli et al., 2018. Brazilian consensus for the diagnosis, treatment and prognosis of cutaneous mast cell tumors in dogs. Investigacao, 17: 1-15.
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Dos Anjos, D.S., A.F. Vital, P.D.F. Lainetti, A.F. Leis-Filho and F. Dalmolin et al., 2019. Deregulation of VEGFR-2 and PDGFR expression and microvascular density in a triple-negative model of canine malignant mammary tumors with lymph node or lung metastasis. Vet. Sci., Vol. 6. 10.3390/vetsci6010003.
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Dos Anjos, D.S., A.R. Assis, C.E. Fonseca-Alves and V.J. Babo-Terra, 2016. Clinical, pathological and immunohistochemical evaluation of a primary hemangiosarcoma in a pinscher dog. Acta Sci. Vet., Vol. 44. .
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Dos Anjos, D.S., J. Santilli, A.F. Vital, J.R. de Oliveira and M.F.D.R. Sobreira et al., 2018. Evaluation of hemostatic parameters in tumor-bearing dogs. Acta Sci. Vet., Vol. 46. 10.22456/1679-9216.89391.
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Dos Anjos, D.S., P.B. Costa, L.F. Magalhaes, O.R. Sierra, S.G. Calazans and C.E. Fonseca-Alves, 2018. Hydroxyurea-induced onychomadesis in a dog with chronic myeloid leukemia: A case report. Top. Companion Anim. Med., 33: 73-76.
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Dos Anjos, D.S., Y.A. Rossi, L.F. Magalhaes, S.G. Calazans and C.E. Fonseca-Alves, 2018. Digital trichoblastoma treated with electrochemotherapy in a dog. Vet. Record Case Rep., Vol. 6. 10.1136/vetreccr-2018-000671.
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Dos Santos, S.O., P.P. Cintra, C. Fonseca-Alves, O.R.S. Matiz, G.M. Magalhaes, A.D.S. Jorge and S.G. Calanzans, 2017. [Undifferentiated carcinoma of the exocrine pancreas in dog: Case report]. Vet. Zootecnia, 24: 303-310.
Elias, F., R.M. Barros, H.L. Santos-Junior, R.S.A. Eloi, V. Silva, F. Freitas and C.E. Fonseca-Alves, 2016. Pathological alterations in dogs resulting from parasitism by Spirocerca lupi. Acta Sci. Vet., Vol. 44. .
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Filho, A.F.L., P.F. Lainetti, M.A. Cyrino, P.E. Kobayashi and C.D. Costa et al., 2018. Primary diffuse mammary hemangiosarcoma in a female dog. Braz. J. Vet. Pathol., 11: 102-107.
Fonseca-Alves, C.E. and S.G. Calazans, 2016. Metronomic chemotherapy in small animal practice: An update. Asian J. Anim. Vet. Adv., 11: 17-23.
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Fonseca-Alves, C.E., A.G. Correa, H.L. Santos-Junior, F. Elias, S.S. Costa and V.M.B.D. De Moura, 2012. Prostatic abscess in dogs: Report of 15 cases. Semina Ciencias Agrarias, 33: 1157-1164.
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Fonseca-Alves, C.E., A.G. Correa, H.X. Costa, H.L. Santos-Junior, F. Elias, S.S. Costa and S.G. Calazans, 2012. Juvenile cellulitis in a puppy-case reports. Semina Ciencias Agrarias, 33: 1165-1168.
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Fonseca-Alves, C.E., A.G. Correia and F. Elias, 2012. Eosinophilic gastroenteritis in basset hound dog. Open J. Anim. Sci., 20: 110-112.
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Fonseca-Alves, C.E., F. Elias and S.G. Calazans, 2014. Cyclooxygenase inhibitor associated with carboplatin in treatment of metastatic nasal carcinoma in dog. Case Rep. Vet. Med. 10.1155/2014/817930.
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Fonseca-Alves, C.E., F. Elias and H.L. Santos-Junior, 2011. Therapeutic protocol for canine liver cirrhosis-use in three animals. Biol. Stud., 33: 39-43.
Fonseca-Alves, C.E., G.G. Guiraldelli, G.G. Fernandes, P.D. Cosentino, A.F. Leis Filho and P.F. Lainetti, 2018. Long-term survival in two dogs with intracranial meningioma treated with lomustine and prednisone. Int. J. Vet. Anim. Med., 1: 1-2.
Fonseca-Alves, C.E., I.S.T. Vicente, S.G. Calazans and R. Laufer-Amorim, 2013. Canine prostate cancer: Would the dog be an important model for the study of new drugs? Am. J. Drug Discovery Dev., 3: 220-224.
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Fonseca-Alves, C.E., M.B.R. Faleiro, R. Laufer Amorim and V.M.B.D De Moura, 2010. Prostatic histological evaluation in adult not castrated dogs. Arq. Bras. Med. Vet. Zootec., 62: 596-602.
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Fonseca-Alves, C.E., M.G. Possa, F. Bernardi, H.L. Santos-Junior, R.S.A. Eloi and F. Elias, 2017. Histopathological and immunohistochemical evaluation of primary muscular peripheral T cell lymphoma in a dog. Acta Sci. Vet., Vol. 45. .
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Fonseca-Alves, C.E., M.M.P. Rodrigues, V.M.B.D. de Moura, S.R. Rogatto and R. Laufer-Amorim, 2013. Alterations of C-MYC, NKX3.1 and E-cadherin expression in canine prostate carcinogenesis. Microscopy Res. Technique, 76: 1250-1256.
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Fonseca-Alves, C.E., P.E. Kobayashi and R. Laufer-Amorim, 2018. Evaluation of NKX3. 1 and C-MYC expression in canine prostatic cancer. Res. Vet. Sci., 118: 365-370.
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Fonseca-Alves, C.E., P.E. Kobayashi, C. Palmieri and R. Laufer-Amorim, 2017. Investigation of c-KIT and Ki67 expression in normal, preneoplastic and neoplastic canine prostate. BMC Vet. Res., Vol. 13. 10.1186/s12917-017-1304-0.
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Fonseca-Alves, C.E., P.E. Kobayashi, L.G.R. Calderon and R. Laufer-Amorim, 2015. Evidence of epithelial-mesenchymal transition in canine prostate cancer metastasis. Res. Vet. Sci., (In Press). 10.1016/j.rvsc.2015.03.001.
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Fonseca-Alves, C.E., P.E. Kobayashi, L.G.R. Calderon, S.L. Felisbino and J.D.C. Rinaldi et al., 2018. Immunohistochemical panel to characterize canine prostate carcinomas according to aberrant p63 expression. PLoS One, Vol. 13. 10.1371/journal.pone.0199173.
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Fonseca-Alves, C.E., S.C.M.C. Carneiro and V.T. Vidotto, 2011. Reintroduction in nature of giant anteater (Myrmecophaga tridactyla) after osteosynthesis of radius and ulna. Biol. Stud., 33: 39-43.
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Franzoni, M.S., A. Brandi, J.K.D.O.M. Prado, F. Elias and F. Dalmolin et al., 2019. Tumor-infiltrating CD4+ and CD8+ lymphocytes and macrophages are associated with prognostic factors in triple-negative canine mammary complex type carcinoma. Res. Vet. Sci., 126: 29-36.
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Gorricho, C.M., M.R. Tavares, M. Apparicio, C.E. Fonseca‐Alves, B.I. Macente, C.F. Mansano and G.H. Toniollo, 2018. Vitrification of cat ovarian tissue: Does fragment size matters? Reprod. Domestic Anim., 53: 125-132.
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Hood, G., R. Laufer-Amorim, C.E. Fonseca-Alves and C. Palmieri, 2016. Overexpression of ephrin A3 receptor in canine prostatic carcinoma. J. Comp. Pathol., 154: 180-185.
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Iessi, I.L., Y.K. Sinzato, F.Q. Gallego, B. Dallaqua and R.L. Amorim et al., 2015. In vivo analysis of oxidative stress relationship in embryofetal pancreas development of the offspring of diabetic rats. Placenta, 36: 519-519.
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Jardim, J., P.E. Kobayashi, P.D. Cosentino, A. Alcaraz, R. Laufer-Amorim and C.E. Fonseca-Alves, 2018. Clinicopathological and immunohistochemical description of an intrapelvic hepatoid gland carcinoma in a 14-year-old Teckel dog. Vet. Q., 38: 9-13.
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Jark, P.C., T.M.M. Raposo, C.E. Fonseca-Alves, B.I. Macente, R.R. Gutierrez, A.B. de Nardi, R. Laufer-Amorim and M.T. Costa, 2014. Neoadjuvant chemotherapy with vinblastine and lomustine in the treatment of a canine cutaneous mast cell tumous with multiple negative prognostic factors and survival over two years. Revista Portuguesa Ciencias Veterinarias, 108: 587-588.
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Kobayashi, P.E., C.E. Fonseca-Alves, L.G. Rivera-Calderon and R. Laufer-Amorim, 2017. [Carcinogenic process of canine prostate: WNT canonical pathway and its comparative study]. Vet. Zootecnia, 24: 49-59.
Kobayashi, P.E., C.E. Fonseca-Alves, L.G. Rivera-Calderon, M. Carvalho, H. Kuasne, S.R. Rogatto and R. Laufer-Amorim, 2018. Deregulation of E-cadherin, β-catenin, APC and Caveolin-1 expression occurs in canine prostate cancer and metastatic processes. Res. Vet. Sci., 118: 254-261.
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Kobayashi, P.E., M.M. Rodrigues, F. Gartner, A. Rema, C.E. Fonseca-Alves and R. Laufer-Amorim, 2019. Association between decreased expression of estrogen receptor alpha, androgen receptor and phosphatase and tensin homolog immunoexpression in the canine prostate. Pesq. Vet. Bras., 39: 40-46.
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Kubota, L.E., G.M. Magalhaes, P.P. Cintra, S.G. Calazans, F. Elias and C.E. Fonseca-Alves, 2016. [Inflammatory mammary carcinoma-A comparative approach]. Arq. Cienc. Vet. Zool. UNIPAR, 19: 187-194.
Laufer-Amorim, R., A.F. Busso, S.M. Silveira, C.E. Fonseca-Alves, M.M.P. Rodrigues and S.R. Rogatto, 2012. Genomic copy number variation in proliferative, preneoplastic and neoplastic prostate lesions of the dog. Proceedings of the American College of Veterinary Pathologists Annual Meeting, December 1-5, 2012, Washington, USA -.
Laufer-Amorim, R., C.E. Fonseca-Alves, M.M.P. Rodrigues, V.M.B.D. De Moura and S.R. Rogatto, 2012. Immunohistochemical evaluation of C-Myc, Nkx3.1 and E-Cadherin in canine prostatic lesions. Proceedings of the American College of Veterinary Pathologists Annual Meeting, December 1-5, 2012, Washington -.
Laufer-Amorim, R., C.E. Fonseca-Alves, R.A.R. Villacis, S.A.D. Linde and M. Carvalho et al., 2019. Comprehensive genomic profiling of androgen-receptor-negative canine prostate cancer. Int. J. Mol. Sci., Vol. 20. 10.3390/ijms20071555.
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Laufer-Amorim, R., R.B. Ferioli, C.E. Fonseca-Alves, R. Torres Neto, R. Malagoli and S.R. Rogatto, 2012. IGF-1, M-TOR, SCF and C-kit receptor protein expression in canine cutaneous mast cell tumors in tissue microarray slides. Proceedings of the American College os Veterinary Pathologists Annual Meeting, December 1-5, 2012, Washington, USA -.
Lima, A.M.V., N.S.T. Chaves, A.V.C. Amaral, J.M. Moraes and C.E. Fonseca-Alves, 2011. Tear production and conjunctival goblet cell density in shih-tzu dogs. J. Anim. Sci., 129: 353-358.
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Neves, J.P.L., A.E.D.S. Silveira, N.S. Rocha, L.F. Crocomo, C.E. Fonseca-Alves, F.G.O. da Silva and W.C.M. Filho, 2016. [Enterocutaneous fistula in a mare-Case roport]. Vet. Zootecnia, 23: 209-214.
Neves, J.P.L., A.E.S. Silveira, N.S. Rocha, L.F. Crocomo and C.E. Fonseca-Alves et al., 2016. [Photosensitization in a kid goat-Case report]. Vet. Zootecnia, 23: 588-593.
Palmieri, A., G. Hood, M. Brennan, C.E. Fonseca-Alves, R. Laufer-Amorim and R. Allavena, 2019. Tumour-infiltrating T cells are increased in canine prostate cancer tissue: Potential prognostic implications? J. Comp. Pathol., 166: 127-127.
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Palmieri, C., G. Hood, C.E. Fonseca-Alves, R. Laufer-Amorim and R. Allavena, 2019. An immunohistochemical study of T and B lymphocyte density in prostatic hyperplasia and prostate carcinoma in dogs. Res. Vet. Sci., 122: 189-192.
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Palmieri, C., R. Foster, V. Grieco, C.E. Fonseca-Alves and G. Wood et al., 2019. Pathology of the canine prostate: Recommendations of an oncology/pathology working group. J. Comp. Pathol., 166: 100-100.
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Palmieri, C., R.A. Foster, V. Grieco, C.E. Fonseca-Alves and G.A. Wood et al., 2019. Histopathological terminology standards for the reporting of prostatic epithelial lesions in dogs. J. Comp. Pathol., 171: 30-37.
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Pfeifer, J.P., V.H. Santos, G. Rosa, J.B. Souza and M.J. Watanabe et al., 2019. Isolation, cultivation and immunofluorescence characterization of lamellar keratinocytes from equine hoof by using explants. Pesq. Vet. Bras., 39: 292-298.
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Porto, R.N.G., V.M.B.D. De Moura, A.P.I. Santin, C.E.F. Alves and T.P. Sales et al., 2008. Canine lymphocytic thyroiditis in a Bull Terrier. Acta Sci. Vet., 36: 285-288.
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Rivera-Calderon, L.G., C.E. Fonseca-Alves, P.E. Kobayashi, M. Carvalho, R.O. Vasconcelos and R. Laufer-Amorim, 2019. p-mTOR, p-4EBP-1 and eIF4E expression in canine prostatic carcinoma. Res. Vet. Sci., 122: 86-92.
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Rivera-Calderon, L.G., C.E. Fonseca-Alves, P.E. Kobayashi, M. Carvalho, S.A. Drigo, R.D.O. Vasconcelos and R. Laufer-Amorim, 2016. Alterations in PTEN, MDM2, TP53 and AR protein and gene expression are associated with canine prostate carcinogenesis. Res. Vet. Sci., 106: 56-61.
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Story, M., C.E. Fonseca-Alves, B.W. Stringer, R. Straw, A.M. de Marzo, R. Laufer-Amorim and C. Palmieri, 2019. Immunophenotype of proliferative inflammatory atrophy (PIA) in the canine prostate. J. Comp. Pathol., 166: 110-110.
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Vicente, I.S.T. and C.E. Fonseca-Alves, 2013. Impact of introduced nile tilapia (Oreochromis niloticus) on non-native aquatic ecosystems. Pak. J. Biol. Sci., 16: 121-126.
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Vicente, I.S.T., F. Elias and C.E. Fonseca-Alves, 2013. Zinc-responsive dermatosis in a mixed breed dog. J. Vet. Adv., 3: 325-328.
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