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    Publisher: Asian Network for Scientific Information
   
  International Journal of Pharmacology (IJP) is an internationally recognized Journal, contains peer-review material and provides broad coverage of all aspects of the interactions of drugs and medicines with biological systems (chemical, physiological and behavioral effects); including autonomic, behavioral, cardiovascular, cellular, clinical, developmental, gastrointestinal, immuno-, neuro-, pulmonary, and renal pharmacology, as well as analgesics, drug abuse, metabolism and disposition, chemotherapy, and toxicology, pharmaceuticals, neutraceuticals, immunomodulation, vaccines and vaccines based therapies, pharmacogenomics aided drug development and therapeutics, pharmacokinetics, pharmacodynamics, modes of action and metabolism of effective drugs and medicines, various upcoming drug designing and novel drug delivery methods. It also emphasizes frontiers in therapeutic advances and their biomedical perspectives including advances and recent trends in various prophylactic and therapeutic regimens to effectively combat various diseases and other health problems, both infectious and non-infectious posing challenge to the humans and their companion animals. Novel, emerging and valuable alternate / complementary therapeutic options with interdisciplinary approaches of biotechnology, molecular aspects of drug actions, mechanism and toxicity, genetics, cellular immunology, immunomics, proteomics, pharmacology, bioinformatics, nanotechnology would be the given due focus.

International Journal of Pharmacology now accepting new submissions. Submit your best paper via online submission system.

  Founder Editor-in-Chief:  Mohammad Abdollahi
 
 
Abbas, A., K. Arif-ullah, F. Ali, H. Afzal and K. Imran, 2017. Synthesis, characterization, antioxidant, antimicrobial, cytotoxic, anticancer, leishmanicidal, anti-inflammatory activities and docking studies of heterocyclic 1,3,4-oxadiazoles and 4-amino-1,2,4-triazoles derivatives. J. Chem. Soc. Pak., .
Afridi, F., K. Arif-ullah, F. Ali and H. Nadeem, 2017. In-silico, invitro and in-vvo investigation of novel oxadiazole and pyrazole derivatives. BMC Pharmacol. Toxicol., .
Ahmad, I., A.U. Khan, B.A. Chaudhary, K.H. Janbaz and M. Uzair et al., 2012. Antifungal and antispasmodic activities of the extracts of Euphorbia granulata. J. Med. Plants Res., 6: 19-23.
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Ali, F., I. Ali, H. Khan, K. Arif-ullah and A.H. Gilani, 2011. Studies on Buddleja asiatica antibacterial, antifungal, antispasmodic and Ca++ antagonist activities. Afr. J. Biotechnol., 10: 7679-7683.
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Arif, N., H. Nadeem, Z.R. Paracha, F. Ali and K. Arif-ullah, 2017. Synthesis, anti-inflammatory activity and docking analysis of 4,5-disubstituted-1,2,4-triazole thioacetate derivatives. Arabian J. Chem., .
Arif-ullah K and A.H. Gilani, 2008. Pharmacodynamic evaluation of Terminalia bellerica for its antihypertensive effect. J. Food Drug Anal., 16: 6-14.
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Arif-ullah, K and A.H. Gilani, 2008. Cardiovascular inhibitory effects of Hyoscyamus niger. Meth. Findings Exp. Clin. Pharmacol., 30: 295-300.
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Arif-ullah, K and A.H. Gilani, 2010. Analgesic and antisecretory activities of Terminalia bellerica. Afr. J. Biotechnol., 9: 2717-2719.
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Arif-ullah, K and A.H. Gilani, 2010. In vivo studies on bronchodilatory and analgesic activities of Hysocyamus niger and Aspalathus linearis. Latin Am. J. Pharm., 29: 777-782.
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Arif-ullah, K and A.H. Gilani, 2011. Pharmacological basis for the use of Valeriana wallichii in constipation. Latin Am. J. Pharm., 30: 186-188.
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Arif-ullah, K and A.H. Gilani, 2015. Natural products useful in respiratory disorders: focus on side-effect neutralizing combinations. Phytother. Res., 29: 1265-1285.
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Arif-ullah, K and A.H. Gilani, 2015. Urinary bladder relaxant effect of Artemisia vulgaris and Aspalathus linearis. J. Anim. Plant Sci., 25: 1779-1781.
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Arif-ullah, K., A.H. Gilani and N. Rehman, 2011. Pharmacological studies on Hypericum perforatum fractions and constituents. Pharm. Biol., 49: 46-56.
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Arif-ullah, K., A.H. Gilani, S. Ali, M. Ahmed, A.K. Marwat and M.I. Choudhary, 2017. Antispasmodic, bronchodilator, vasorelaxant and cardiosuppressant effects of Buxus papillosa. BMC Complementary Altern. Med., 10.1186/s12906-017-1558-x.
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Arif-ullah, K., F. Ali, D. Faraz and A.H. Gilani, 2011. Gut modulatory effects of Daphne oleoides are mediated through cholinergic and Ca++ antagonist mechanisms. Pharm. Biol., 49: 821-825.
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Arif-ullah, K., M.R. Mustafa, A. Khan and D.D. Morgan, 2012. Hypotensive effect of Gentiana floribunda is mediated through Ca++ antagonism pathway. BMC Complementary Alter. Med., 10.1186/1472-6882-12-121.
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Arif-ullah, K., U. Riaz, A. Khan, M.R. Mustafa, J. Hussain, D.D. Murugan and A.H.B. Hadi, 2012. Vasodilator effect of Phlomis bracteosa constituents is mediated through dual endothelium-dependent and-independent pathways. Clin. Exp. Hypertens., 34: 132-139.
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Aslam, H., H. Aslam and K. Arif-ullah, 2017. Computational evaluation of selected natural compounds for antidiabetic potential. Front. Pharmacol., .
Aslam, H., K. Arif-ullah and F. Ali, 2017. In-vitro and in-vivo pharmacological investigation of Conyza canadensis for its anti-diabetic effect. BMC Complementary Altern. Med., .
Aslam, H., K. Arif-ullah, F. Ali, H. Nadeem and S.M. Shah, 2017. Anti-diabetic activity of Heliotropium strigosum in alloxan-induced diabetic mice. Asian Biomed., .
Ayaz, M., F. Subhan, J. Ahmed, A. Khan and F. Ullah et al., 2015. Sertraline enhances the activity of antimicrobial agents against pathogens of clinical relevance. J. Biol. Res. Thessaloniki, 10.1186/s40709-015-0028-1.
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Ayaz, M., F. Subhan, J. Ahmed, K. Arif-ullah and U. Farhat et al., 2015. Citalopram and venlafaxene differentially augments antimicrobial properties of antibiotics. Acta Poloniae Pharm. Drug Res., 72: 1269-1278.
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Farman, K., K. Arif-ullah, A. Khan, J. Hussain and A.H. Gilani, 2016. Spasmolytic and Ca++ channel blocking potential of nepetolide: Isolated from nepeta suavis. Nat. Prod. Commun., 11: 591-592.
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Firdoos, S., K. Arif-ullah and F. Ali, 2017. Anti-nociceptive effect of caralluma edulis on peripheral and central pain pathways-possible underlying pharmacodynamics. Sains Malaysiana, .
Firdoos, S., K. Arif-ullah and F. Ali, 2017. Pharmacological investigation of Aesculus indica for its anti-nociceptive action. J. Anim. Plant Sci., .
Gilani, A.H., A. Khan, A. Khan, S. Bashir and N. Rehman et al., 2010. Pharmacological basis for the medicinal use of Holarrhena antidysenterica in gut motility disorders. Pharm. Biol., 48: 1240-1246.
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Gilani, A.H., A. Khan, F. Subhan and M. Khan, 2005. Antisposmodic and bronchodilator activities of St. Johns Wort are putatively mediated through dual inhibition of calcium influx and phosphodiaestrases fund. Clin. Pharmacol. J. Compilat., 19: 695-705.
Gilani, A.H., A. Khan, M.N. Ghayur, S.F. Ali and J.W. Herzig, 2006. Antispasmodic Effects of Rooibos Tea (Aspalathus linearis) is Mediated Predominantly through K+-Channel Activation. Basic Clin. Pharmacol. Toxicol., 99: 365-373.
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Gilani, A.H., A.U. Khan, A.J. Shah, J. Connor and Q. Jabeen, 2005. Blood pressure lowering effect of olive is mediated through calcium channel blockade. Int. J. Food Sci. Nutr., 56: 613-620.
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Gilani, A.H., A.U. Khan, M. Raoof, M.N. Ghayur, B.S. Siddiqui, W. Vohra and S. Begum, 2008. Gastrointestinal, selective airways and urinary bladder relaxant effects of Hyoscyamus niger are mediated through dual blockade of muscarinic receptors and Ca2+ channels. Fundam. Clin. Pharmacol., 22: 87-99.
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Gilani, A.H., A.U. Khan, Q. Jabeen, F. Subhan and R. Ghafar, 2005. Antispasmodic and blood pressure lowering effects of Valeriana wallichii are mediated through K+ channel activation. J. Ethnopharmacol., 100: 347-352.
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Gilani, A.H., A.U. Khan, T. Ali and S. Ajmal, 2008. Mechanisms underlying the antispasmodic and bronchodilatory properties of Terminalia bellerica fruit. J. Ethnopharmacol., 116: 528-538.
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Gilani, A.H., I.A. Bukhari, R.A. Khan, A.U. Khan, F. Ullah and V.U. Ahmad, 2005. Cholinomimetic and calcium channel blocking activities of Carthamus oxycantha. Phytother. Res., 19: 679-683.
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Gilani, A.H., K. Arif-ullah and M.N. Ghayur, 2006. Ca2+ antagonist and cholinergic activities explain the medicinal use of olive in gut disorders. Nutr. Res., 26: 277-283.
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Gilani, A.H., K.H. Bashir, K.H. Janbaz and A. Khan, 2005. Pharmacological basis for the use of fumaria indica in constipation and disrrheoa. J. Ethnopharmacol., 96: 585-589.
Gilani, A.H., M.H. Mehmood, K.H. Janbaz, A. Khan and S.A. Saeed, 2009. Gut modulatory and antiplatelet activities of Viscum cruciatum. Pharm. Biol., 47: 955-961.
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Gilani, A.H., M.H. Mehmood, K.H. Janbaz, A.U. Khan and S.A. Saeed, 2008. Ethnopharmacological studies on antispasmodic and antiplatelet activities of Ficus carica. J. Ethnopharmacol., 119: 1-5.
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Gilani, A.H., Q. Jabeen, A.U. Khan and A.J. Shah, 2008. Gut modulatory, blood pressure lowering, diuretic and sedative activities of cardamom. J. Ethnopharmacol., 115: 463-472.
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Gilani, A.H., S. Bashir and A.U. Khan, 2007. Pharmacological basis for the use of Borago officinalis in gastrointestinal, respiratory and cardiovascular disorders. J. Ethnopharmacol., 114: 393-399.
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Gilani, S.N., A.U. Khan and A.H. Gilani, 2010. Pharmacological basis for the medicinal use of Zanthoxylum armatum in gut, airways and cardiovascular disorders. Phytother. Res., 24: 553-558.
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Haq, R.U., I.U. Shah, Z. Ullah, R.A. Khan and A. Malik, 2012. Antitussive and toxicological evaluation of Vitex negundo. Natural Prod. Res., 26: 484-488.
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Hussain, J., F. Khan, I. Khan, Riazullah and K. Arif-ullah, 2010. Antifungal and Immunomodulatory potential of Nepeta suavis. Am. Eurasian J. Agric. Environ. Sci., 7: 689-692.
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Hussain, J., F.U. Khan, S.A. Gilani, G. Abbas and S. Ahmed et al., 2010. Antiglycation, antiplatelets aggregation, cytotoxic and phytotoxic activities of Nepeta suavis. Latin Am. J. Pharmacy, 29: 573-578.
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Hussain, J., R. Ullah, A. Khan, F. Mabood, M.R. Shah, A.A. Harrasi and A.H. Gilani, 2011. Antispasmodic and Ca++ antagonist potential of marrubiin, a labdane type diterpene from Phlomis bracteosa. J. Pharm. Res., 4: 178-180.
Hussain, M., K. Arif-ullah, N.G. Qazi and F. Ali, 2017. Pharmacological basis for the medicinal use of Ziziphus nummularia in gastrointestinal disorders. Front. Pharmacol., .
Hussain, S., M. Jamil, F. Ullah, A. Khan, F. Ullah and S. Ahmed, 2010. Antimicrobial and antioxidant activities of the plant Heliotropium strigosum. Afr. J. Biotechnol., 9: 7738-7743.
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Hussain, S., U. Farhat and K. Arif-ullah, 2017. In vitro cytotoxicity of crude and subsequent fractions of Anchusa arvensis against human lung cancer cell line NCI-H460. (UITO-2016-0440). Int. J. Toxicol., .
Ismail, A., J. Hussain, K. Arif-ullah, A.L. Khan and L. Ali et al., 2012. Antibacterial, antifungal, cytotoxic, phytotoxic, insecticidal, and enzyme inhibitory activities of Geranium wallichianum. Evidence-Based Complementary Alter. Med., 10.1155/2012/305906.
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Khan, A. and A.H. Gilani, 2006. Selective bronchodilatory effect of Rooibos tea (Aspalathus linearis) and its flavonoid, chrysoeriol. Eur. J. Nutr., 45: 463-469.
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Khan, A. and A.H. Gilani, 2009. Antidiarrheal, antisecretory, and bronchodilatory activities of Hypericum perforatum. Pharm. Biol., 47: 962-967.
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Khan, A. and A.H. Gilani, 2010. Airways and cardiovascular inhibitory effects of Olea europea and Terminalia bellerica aqueous fractions. Farmacia, 58: 758-763.
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Khan, A. and A.H. Gilani, 2011. Antidiarrheal and bronchodilatory activities of olive extract. Latin Am. J. Pharm., 30: 5-9.
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Khan, A. and A.H. Gilani, 2012. Antidiarrhoeal and bronchodilatory potential of Valeriana wallichii. Nat. Prod. Res., 26: 1045-1049.
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Khan, A., A. Rahim, Z. Iqbal and A.H. Gilani, 2012. Insights into mechanisms underlying the gut and airways modulatory effects of Swertia chirata. J. Nat. Med., 66: 140-148.
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Khan, A., A.H. Gilani, M. Khan and F. Subhan, 2011. Pharmacological explanation for medicinal use of St. John's Wort in the hypo-motility disorder of gut. Latin Am. J. Pharm., 30: 580-583.
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Khan, A., M. Khan, F. Subhan and A.H. Gilani, 2010. Antispasmodic, bronchodilator and blood pressure lowering properties of Hypericum oblongifolium - possible mechanism of action. Phytother. Res., 24: 1027-1032.
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Khan, A., M. Mehwis, S. Wadood and K. Arif-ullah, 2017. The in silico identification of small molecules for protein-protein interaction inhibition in AKAP-Lbc-RhoA signaling complex. Comput. Biol. Chem., 67: 84-91.
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Khan, A., Q.J. Khan and A.H. Gilani, 2011. Pharmacological basis for the medicinal use of cardamom in asthma. Bangladesh J. Pharmacol., 6: 34-37.
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Khan, A.U. and A.H. Gilani, 2009. Antispasmodic and bronchodilator activities of Artemisia vulgaris are mediated through dual blockade of muscarinic receptors and calcium influx. J. Ethnopharmacol., 126: 480-486.
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Khan, A.U. and A.H. Gilani, 2011. Blood pressure lowering, cardiovascular inhibitory and bronchodilatory actions of Achillea millefolium. Phytother. Res., 25: 577-583.
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Khan, A.W and K. Arif-ullah, 2017. Phytochemical composition and antidepressant action of Solanum surattense. J. Herbs Spices Med. Plants, .
Khan, A.W., K. Arif-ullah and T. Ahmed, 2016. Anticonvulsant, anxiolytic, and sedative activities of verbena officinalis. Front. Pharmacol., 7: 1-8.
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Khan, H., I. Ali, K. Arif-ullah, M. Ahmed and Z. Shah et al., 2010. Purification and biochemical characterization of alkaline serine protease from Caesalpinia bonducella. Nat. Prod. Commun., 5: 931-934.
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Khan, H.U., I. Ali, A.U. Khan, R. Naz and A.H. Gilani, 2011. Antibacterial, antifungal, antispasmodic and Ca++ antagonist effects of Caesalpinia bonducella. Nat. Prod. Res., 25: 444-449.
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Khan, I.U., J.A. Khader, F.U. Khan, K. Arif-ullah and U. Muhib et al., 2013. Carbonic anhydrase and urease inhibitory effects of Sonchus asper. Life Sci. J., 10: 2705-2707.
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Khan, M., F. Subhan, K. Arif-ullah, M. Abbas, G. Ali, K. Rauf and A.H. Gilani, 2014. Nature cures nature: Hypericum perforatum attenuates physical withdrawal signs in opium dependent rats. Pharm. Biol., 52: 586-590.
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Khan, M., K. Arif-ullah, N. Rehman and A.H. Gilani, 2012. Gut and airways relaxant effects of Carum roxburghianum. J. Ethnopharmacol., 141: 938-946.
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Khan, M., K. Arif-ullah, N. Rehman and A.H. Gilani, 2012. Pharmacological explanation for the medicinal use of Juniperus excelsa in hyperactive gastrointestinal and respiratory disorders. J. Nat. Med., 66: 292-301.
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Khan, M., K. Arif-ullah, N. Rehman and A.H. Gilani, 2014. Blood pressure lowering Morus alba is mediated through Ca++ antagonist pathway. Int. J. Pharmacol., 10: 225-230.
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Khan, M., K. Arif-ullah, N. Rehman and A.H. Gilani, 2014. Cardiovascular inhibitory properties of Lens culinaris. Bangladesh J. Pharmacol., 9: 303-306.
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Khan, M., K. Arif-ullah, N. Rehman and A.H. Gilani, 2014. Pharmacological basis for the medicinal use of Lens culinaris in gastrointestinal and respiratory disorders. Phytother. Res., 28: 1349-1358.
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Khan, M., K. Arif-ullah, N. Rehman and A.H. Gilani, 2015. Blood pressure lowering, vasodilator and cardiac-modulatory potential of Carum roxburghianum seed extract. Clin. Exp. Hypertens., 37: 102-107.
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Khan, M., K. Arif-ullah, N. Rehman, M.A. Zafar, A. Hazrat and A.H. Gilani, 2012. Cardiovascular effects of Juniperus excelsa are mediated through multiple pathways. Clin. Exp. Hypertens., 34: 209-216.
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Khan, M., Najeeur-Rehman, K. Arif-ullah and A.H. Gilani, 2012. Pharmacological basis for the medicinal use of Morus alba in gut and airways disorders. Bangladesh J. Pharmacol., 7: 289-298.
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Khan, S.U., K. Arif-ullah, A.H.A. Shah, S.M. Shah, S. Hussain, M. Ayaz and S. Ayaz, 2016. Heavy metals content, phytochemical composition, antimicrobial and insecticidal evaluation of Elaeagnus angustifolia. Toxicol. Ind. Health, 32: 154-161.
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Minhas, A.M., K. Arif-ullah and G.A. Miana, 2017. Anti-inflammatory activity of Berberis lycium in acute and chronic models of inflammation. J. Anim. Plant Sci., .
Minhas, A.M., K. Arif-ullah and M.M. Ansari, 2017. Anti-inflammatory effect of Caralluma edulis in acute and chronic inflammation; An explanation of possible underlying biochemical mechanisms. J. Anim. Plant Sci., .
Najeeb-ur-Rehman, K. Arif-ullah, K.M. Alkharfy and A.H. Gilani, 2012. Pharmacological basis for the medicinal use of Lepidium sativum in airways disorders. Evidence-Based Complementary Altern. Med., 10.1155/2012/596524.
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Qazi, N.G., K. Arif-ullah and F. Ali, 2017. Pharmacological basis for medicinal use of Acacia modesta in hyperactive gastrointestinal disorders. BMC Pharmacol. Toxicol., .
Rahman, N., M. Riaz, K. Arif-ullah, Z. Haq and L. Dima, 2015. Mechanism of anti-inflammatory and anti-nociceptive actions of Acacia modesta in animal models. Pak. J. Zool., 47: 1723-1730.
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Raza, Q., K. Arif-ullah and H. Nadeem, 2017. In-silico investigation, in-vivo anticonvulsant and analgesic effects of novel hydrazide derivatives. Acta Poloniae Pharm. Drug Res., .
Rehman, S., Z. Awan, K. Arif-ullah, A.H. Shah, A. Rahman and I. Gul, 2012. Antibacterial potential of Skemmia laureola methanolic extract. Global Adv. Res. J. Microbiol., 1: 90-93.
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Saleem, M., K. Arif-ullah, F. Ali and F. Noreen, 2017. Protective effect of Parthenium hysterophorus against carbon tetrachloride and paracetamol-induced hepatotoxicity in rabbits. Trop. J. Pharm. Res., .
Shah, S.M., M. Ayaz, A. Khan, F. Ullah and Farhan et al., 2015. 1,1-Diphenyl,2-picrylhydrazyl free radical scavenging, bactericidal, fungicidal and leishmanicidal properties of Teucrium stocksianum. Toxicol. Ind. Health, 31: 1037-1043.
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Shah, S.M., S. Hussain, A. Khan, A.H.A. Shah, H. Khan, F. Ullah and Barkatullah, 2015. Cytotoxic and phytotoxic actions of Heliotropium strigosum. Toxicol. Ind. Health, 31: 429-432.
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Subhan, F., M. Khan, M. Ibrar, Nazar-ul- Islam, A. Khan and A.H. Gilani, 2007. Antagonism of antinociceptive effect of hydro-ethanolic extract of Hypericum perforatum Linn. By a non selective opioid receptor antagonist, Naloxone. Pak. J. Biol. Sci., 10: 792-796.
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Tanzeel-ur-Rehman, K. Arif-ullah and A. Abbas, 2017. Antioxidant, antimicrobial, cytotoxic, anticancer, anti-inflammatory, analgesic activities and molecular docking investigation of nepetolide: A natural diterpene. Nat. Prod. Commun., .
Ullah, Z., K.M. Baloch, J.A. Khader, N.M. AbdElsalam and K. Arif-ullah et al., 2012. Comparative analysis of distinct diuretics through urine analysis. Afr. J. Pharm. Pharmacol., 6: 1977-1981.
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Yaeesh, S., Q. Jamal, A.U. Khan and A.H. Gilani, 2006. Studies on hepatoprotective, antispasmodic and calcium antagonist activities of the aqueous-methanol extract of Achillea millefolium. Phytother. Res., 20: 546-551.
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