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Articles by Zakia Sultana Sathi
Total Records ( 4 ) for Zakia Sultana Sathi
  M. Ibrahim Khalil , Md. Abdul Motallib , A. S. M. Anisuzzaman , Zakia Sultana Sathi , M. A. Hye and M. Shahjahan
  The antibacterial activities of five different brands of unifloral honey from the Northern region of Bangladesh were investigated. The honeys were from Litchi (Litchi shinensis), Kadom (Anthocephalus cadmba), Til (Seasamum indicum), Plum (Zizyphus mauritiana) and Mustard (Brassica campestris) flowers. It was found that the tested unifloral honeys showed a significant antibacterial activity against the wound infecting and enteric pathogens. Among them honey from Mustard flower was more active.
  M. Ibrahim Khalil , Md. Abdul Motallib , A. S. M. Anisuzzaman , Zakia Sultana Sathi , M. A. Hye and M. Shahjahan
  The research work was conducted to investigate the biochemical composition of five different brands of unifloral honey. The honey from Litchi (Litchi chinensis), Kadom (Anthocephalus cadmba), Til (Sesamum indicum), Plum (Zizyphus mauritiana) and Mustard (Brassica campestris) were used. This paper includes, determination of pH, specific gravity, solubility, moisture content as well as the total and reducing sugar, total protein content, water soluble protein, lipid, ash, dry matter, vitamin A and C and mineral content. It was found that the total content of sugar 77.7-80.30%, reducing sugar 62.30-65.02%, protein 0.30-0.33%, lipid 134-146mg 100 gm-1, vitamin-C 4.8-5.3mg 100 gm-1, pH 3.30 to 4.20, ash 0.65 to 0.80 and specific gravity between 1.33 to 1.36.
  Zakia Sultana Sathi , A. S. M. Anisuzzaman , Golam Sadik and M. A. Gafur
  The subacute toxicity study of an antimicrobial compound, 4-hydroxy nitrobenzene isolated from a Streptomyces species was carried out on long Evan’s rats. The compound, 4-hydroxy nitrobenzene (300μg) was administered daily for 14 days and its effect on body weight, hematological and biochemical parameters of blood was investigated. There was no significant difference between weight gain in rats, receiving compound and control (121±5.10 vs 115±7.2g, respectively). There were no significant changes detected in hematology (red blood cells, 5.63±0.23 vs 4.97±0.17; white blood cells, 12575±170.78 vs 10950±238; platelet, 312500 ± 9574 vs 31000±21602 (cells ml-1)x106; hemoglobin, 13.25±0.3 vs 13.27 ±0.36%, for experimental and control rats, respectively) or blood biochemistry (serum glutamic oxaloacetic transaminase, 11.5±1.29 vs 11.75±1.25IU L-1, serum glutamate pyruvate transaminase, 8.25±1.26 vs 7.25±1.5IU L-1, serum alkaline phosphatase 41.25 ±1.89 vs 44.25 ± 3.3IU L-1. Uric acid, 7.05±0.129 vs 7.3± 0.22; urea, 42.25 ± 1.708 vs 41.5 ± 2.64; creatinine, 0.85±0.05 vs 1.07±0.188mg dL-1, for experimental and control rats, respectively). Therefore, the compound, 4-hydroxy nitrobenzene (300μg day-1) over 14 days, had no toxic effects on rats.
  Zakia Sultana Sathi , Md. Aziz Abdur Rahman and M.A. Gafur
  A pure antimicrobial compound was isolated from the chloroform extract of the broth culture of Streptomyces species by preparative thin layer chromatography (PTLC) and was characterized as 4-hydroxy nitrobenzene (ZS-3) on the basis of spectral data (UV, IR, 1H-NMR, HMBC and HMQC). The compound showed significant antimicrobial activity against six gram positive bacteria, ten gram negative bacteria and three pathogenic fungi. The minimum inhibitory concentration (MIC) of the compound determined against ten pathogenic organisms was found to be between 32-64 g/ml.
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