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Articles by Z.X. Cao
Total Records ( 2 ) for Z.X. Cao
  M. Yu , Z.Y. Ning , Z.X. Cao , R.S. Li , C.L. Huang and G.H. Zhang
  In the present study, researchers describe a rescue system for duck hepatitis virus-1 using T7 RNA polymerase. This strain can not induce typical cytopathic effect in BHK-21 cells. First, there is used the vitro transcripts to infect BHK-21 cells. Then the infected cell supernatant were inoculated into chicken embryos to rescue the virus and the cDNA clone was engineered to contain one silent nucleotide change to create a BssHII site to distinguish from the parental virus. The rescued virus was able to result in embryonic death and have similar infection with parental virus in chicken embryos indicating that the cDNA clones were replication competent. It is proposed that this rescue system may benefit the investigation on viral virulence determinants and molecular virology of DHV-1 virus.
  Z.X. Cao , Z.H. Shi , Y. Zhang , Z. Chao , L.M. Wei , Q.W. Liu , X. Zhang , B.G. Ye , X.L. Zheng , F. Wang and Z.M. Lin
  Porcine Circovirus type 2 (PCV2) is one of the most important swine pathogens of economic importance. To understand the genetic diversity of Porcine Circovirus type 2 (PCV2) in South China, 49 PCV2 sequences from South China were compared to 58 other references sequences. Researchers found that the nucleotide similarity among all South China isolates ranged from 93.7-100%. Most of them were classified into PCV2b-1A/1B cluster but the rest mapped to clusters PCV2b-1C, PCV2a-2E or PCV2a-2F. The data contribute to the understanding of molecular variation of PCV2 in South China.
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