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Articles by Yanyong Liu
Total Records ( 2 ) for Yanyong Liu
  Yanyong Liu , Shuxia Liu , Enbo Wang , Yi Zeng and Zelin Li
  Yanyong Liu , Shuxia Liu , Enbo Wang , Yi Zeng and Zelin Li
  A praseodymium salt of 12-tungstophosphate acid, Pr[PW12O40], was synthesized using ion exchange and double decomposition method. Then its 2e and 4e electrochemically reduced heteropoly blues, PrH2[PWVI10WV2O40] and PrH4[PWVI8WV4O40], were synthesized using control-potential electrolysis reduction method. These compounds were characterized with FT-IR, UV-vis, polarography, ESR and XPS. The α-Keggin type structure was kept in the heteropoly blues PrH2[PWVI10WV2O40] and PrH4[PWVI8WV4O40] but the electronic density of heteropoly anion increased after electrochemically reduction. Heteropoly blues PrH2[PWVI10WV2O40] and PrH4[PWVI8WV4O40] showed relatively high in vitro anti-HIV-1 activity and relatively low cytotoxicity on MT-4 cells compared to some other anti-HIV-1 compounds. Because heteropoly blues possess higher negative electronic charges than their non-reduced parents, they strongly interact with HIV-1, MT-4 cells and macrophages and effectively suppress fusion, infection and proliferation of HIV-1.
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