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Articles by Y.U. Dabai
Total Records ( 4 ) for Y.U. Dabai
  S.W. Hassan , M. Lawal , B.Y. Muhammad , R.A. Umar , L.S. Bilbis , A.A. Ebbo and Y.U. Dabai
  The column chromatographic fractions of chloroform (CHL1, CHL2 and CHL3) root extracts of Boscia angustifolia were screened for antibacterial activity and phytochemical properties. CHL1 fraction was significantly active (p<0.05) at 5 to 60 mg L-1 on Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli and Streptococcus pneumoniae with Minimum Inhibitory Concentration (MIC) of 0.63 to 1.25 mg L-1. The active fraction (CHL1) revealed the presence of only alkaloids with Retention factor (Rf) value of 0.36. The active antibacterial agent in the most potent fraction (CHL1) was isolated and identified by thin layer chromatography (TLC) and phytochemistry. The CHL2 and CHL3 fractions did not show inhibitory activity at 5 to 60 mg L-1. The antibacterial activity of root extract of Boscia angustifolia is due to a chloroform-extractable compound. The results support the ethnomedicinal use of root of Boscia angustifolia for the treatment of bacterial diseases.
  S.W. Hassan , R.A. Umar , Y.U. Dabai , A.A. Ebbo and U.Z. Faruk
  The aqueous and organic solvent leaves extracts of Pteridium aquilinum were screened for antibacterial activity by hole-in-plate bioassay procedure. The effect of aqueous leaves extract of the plant on hepatorenal functions in rabbits was also studied. Hexane (HX) fraction at 10 to 120 mg mL-1 did not show activity against Escherichia coli and Pseudomonas aeruginosa. However, it was significantly (p<0.05) active against Staphylococcus aureus at 90 and 120 mg mL-1. The chloroform (CHL) extract fraction at concentrations of 50-120 mg mL-1 was significantly (p<0.05) active on all the bacterial species. Petroleum ether (PE) at 10-120 mg mL-1 showed significant (p<0.05) inhibition of S. aureus and E. coli. Aqueous (W) extract exhibited significant inhibitory activity at 50-120 mg mL-1 on S. aureus and P. aeruginosa. Tannins, anthraquinone glycosides, cardiac glycosides, cyanogenic glycosides and volatile oils were detected in the extracts. The lethal dose (LD50) of the aqueous leaves extracts was found to be greater than 3000 mg kg-1 (p.o.) in rabbits. Non significant (p>0.05) and significant (p<0.05) changes in renal and liver indices, respectively were observed. Aqueous leaves extract of Pteridium aquilinum is toxic to the liver of rabbits only at 1500-3000 mg kg-1. These results have provided scientific evidence to justify the indigenous use of the plant against infectious diseases.
  O.O. Faleke , Y.A. Yabo , A.O. Olaleye , Y.U. Dabai and E.B. Ibitoye
  The present study was conducted to investigate the point prevalence of Cryptosporidium oocysts infection in calves grazing along the bank of Rima River Sokoto in October 2011. The river bank is a converging zone for domestic animals reared in different quarters of the town and the surrounding settlements. A total number of 2,959 cattle were enumerated out of which 147 (4.97%) were calves. Faecal samples were collected from 100 (68.02%) calves by convenient sampling technique. Formol-Ether sedimentation and modified Ziehl-Neelsen staining techniques were used to identify the Cryptosporidium oocysts in the faecal samples. Faecal consistency was also used to identify diarrhoeic and non-diarrhoeic calves. Cryptosporidium oocysts were identified in 33(33.0%) of the calves examined. The detection rate was higher among the male calves (38.46%) than females while the Rahaji breed had the highest prevalence of 62.5%. A total of 6 (18.18%) among the positive cases were diarrhoeic. The differences in prevalence based on sex, breeds and presence of diarrhoea were not statistically significant. Calves may become sources of Cryptosporidia infection to man and other animals in the study area through unrestricted movements and interactions with the environment.
  A.A. Jimoh , E.B. Ibitoye , Y.U. Dabai and S. Garba
  This study was conducted to investigate in vivo antimicrobial potential of garlic against Clostridium perferinges and resultant promotant effects on performance of the broiler chickens. Garlic powder was used as an alternative to GPAs (Growth Promotant Antibiotics) to prevent subclinical Necrotic Enteritis (NE) due to C. perferinges. 120 day-old broiler chicks were randomly distributed to six treatment groups of 20 chicks each (2 replicates¯10 chicks). Six isonutrient diets supplemented with garlic at graded levels of 0.0, 0.5, 1.0, 1.5, 2.0 and 2.5 g kg-1 were fed to the birds for seven weeks. Data were collected weekly on performance parameters including feed intake, weight gain and feed conversion ratio (FCR). Also, on the 21 35 and 49th days of the study, two birds per group were randomly selected, slaughtered and dissected. 1g of caecal contents per each bird were sampled into labelled sterile sample bottles. The samples were subjected to culturing, bacterial identification and colony counting. All data were subjected to analysis of variance. Results showed that garlic significantly (p>0.05) depressed feed intake (3310 g feed/bird at 1.0 g kg-1 supplementation) but improved FCR. The supplement has no significant effect on weight gain but C. perfringens colony counts in the treated groups, were numerically reduced (lowest count, 0.93x105 cfu g-1 at 1.0 gkg-1 supplementation), as compared to the control. It is therefore concluded that diets could be supplemented with garlic at dose range of 1.0 to 1.5 g kg-1 to prevent subclinical NE and achieve improved performance in birds.
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