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Articles by Xu Feng
Total Records ( 6 ) for Xu Feng
  Wang Dong-Feng and Xu Feng
  Existing test problems for multi-objective optimization are mainly criticized for high computational complexity. In this study, we introduce a new non- dominated sorting algorithm based on Pareto optimal solutions which alleviates the problem of high computational complexity in NSGA-II. We use the Arena Principle in NSGA-II to retain the non-dominated solutions found during the evolutionary process. The main goal of this work is to keep the fast convergence exhibited by Arena Principle in global optimization when extending this heuristic to multi-objective optimization. The algorithm’s computational complexity is O(rmN). We adopt two standard test functions and simulation results show that the Arena Principle is able to find more useful and better spread of solutions.
  Xu Feng and Chen Jianguo
  ANP is the most comprehensive framework for the analysis of societal,national and enterprise decision for the decision-maker today, allowing for all possible and potential dependencies. This study uses ANP model to select cleaner production alternatives on basis of enterprises’ capacity with internal and external dependences. Cleaner Production (CP) has been considered to be an important means for effective pollution control and lead to a win-win situation of improving economic and environmental benefits. It is operated widely by construction enterprises as a method to cut on environment negative impact. However, to select appropriate CP options have been a key issue for different enterprises to implement cleaner production successfully. CP options could be divided into three types: low-cost, mediate-cost, high-cost. Entensive research has studied on evaluation of CP option but most just considered economic and environmental performances of options. In fact,it is important to concider some CP option on basis of enterprises’ background such as CP capacity. This study focused on the relation between the CP capacity of enterprises and CP option, making two contributions: first,we established the evaluation index system of CP capacity in construction enterprises. There is dependence and feedback among elements, so ANP model was used to evaluate. Second, on basis of the complexity of computation process, SuperDesicion software was introduced to calculate the dates and gained the prioritization of the alternatives.
  LI Bi-Chun , Tian Zhi-Quan , Chen Hao , Sun Min , Yang Hai-Yan , Ren Li-Wei , Qin Yu-Rong , Xu Feng and Chen Guo-Hong
  The effect of Dimethylsulphoxide (DMSO), Glycerol (GLY) and Propanedo (PROH) cryoprotectants, each at (10, 20 and 30%) concentration on the preservation of mouse and cattle skin tissue, was investigated. And then, the toxicity test was performed by exposing the skin tissue to DMSO, GLY, PROH, EG without freezing. Tissues were checked by capacity explants. The results indicated that mouse skin tissue frozen in 10% GLY and cattle ear tissue frozen in 20% GLY medium with dry-ice yielded significantly (p<0.05) higher percents (33.3 and 71.4%) of fibroblast than tissue frozen in either concentration of GLY or cryoprotectants. In the toxicity test, mouse skin tissues exposed to GLY and equilibrated at 4°C resulted in higher percent of average explants (41.1%) than that was exposed to PRON and DMSO (average explants 38.3 and 36.5%, respectively), while cattle tissues showed higher toxicity, when exposed to PROH and EG and equilibrated at 4°C (average explants 39.9 and 44.2%, respectively). The present study recommended that 10% GLY with dry-ice freezing was the effective cryoprotectant for the mouse skin tissues, while 20% GLY with dry-ice freezing was effective for cattle skin tissues.
  YANG Dan , QI Shi-Hua , ZHANG Jia-Quan , TAN Ling-Zhi , ZHANG Jun-Peng , ZHANG Yuan , XU Feng , XING Xin-Li , HU Ying , CHEN Wei , YANG Jun-Hua and XU Mei-Hui
  A soil survey was conducted in Zhangzhou City, an important agricultural region in south of the Fujian Province, China. 93 surface soil samples were collected in the paddy fields, vegetable lands, orchards and tea plantations from Zhangzhou City. An additional soil profile was sampled in a paddy field as previous research had indicated high concentrations of organochlorine pesticides (OCPs) in the paddy fields. Dichlorodiphenyltrichloroethanes (DDTs) ranged from 0.64–78.07 ng g−1 dry weight and hexachlorocyclohexanes (HCHs) ranged from 0.72–30.16 ng g−1 dry weight in the surface soil of the whole study region. Ratios of α-HCH/γ-HCH < 4 and o, p′-DDT/p, p′-DDT > 1 in all soil samples suggested that lindane and dicofol were widely applied in this region in the past. Concentrations of HCHs and DDTs in soils from the four land use types followed the orders: paddy fields > vegetable lands > tea plantations > orchards and tea plantations > orchards > paddy fields > vegetable lands, respectively. Analyses of the data showed no correlation (r < 0.1) between elevation and OCPs contents in paddy fields, orchards and vegetable lands, indicated no significantly different features in distribution of HCHs and DDTs in the soils from low lying plains and mountains and the unsystematic usage of OCPs, and highlighted the fragmented nature of agricultural production in Zhangzhou, as well as the reemission of OCPs from the soils, where high OCPs concentrations were found, in Longhai of Zhangzhou. In addition, no obvious relationship between the OCPs and total organic carbon (TOC) (r < 0.3) was observed in the soil profile. The mean contribution of dicofol in total DDTs was 66% in the whole Zhangzhou region. The approximate burdens of HCHs and DDTs in the surface layer of 0–20 cm were 0.44 and 1.55 t, respectively. The storage of both HCHs and DDTs in soil surface layer (0–20 cm) accounts for 40% burden of the soil layer of 0–50 cm (1.10 t HCHs and 3.87 t DDTs), in which the highest concentrations of OCPs were observed in soil profile.
  Yi Zang , Li-Fang Yu , Tao Pang , Lei-Ping Fang , Xu Feng , Tie-Qiao Wen , Fa-Jun Nan , Lin-Yin Feng and Jia Li
  Neural stem cell differentiation and the determination of lineage decision between neuronal and glial fates have important implications in the study of developmental, pathological, and regenerative processes. Although small molecule chemicals with the ability to control neural stem cell fate are considered extremely useful tools in this field, few were reported. AICAR is an adenosine analog and extensively used to activate AMP-activated protein kinase (AMPK), a metabolic "fuel gauge" of the biological system. In the present study, we found an unrecognized astrogliogenic activity of AICAR on not only immortalized neural stem cell line C17.2 (C17.2-NSC), but also primary neural stem cells (NSCs) derived from post-natal (P0) rat hippocampus (P0-NSC) and embryonic day 14 (E14) rat embryonic cortex (E14-NSC). However, another AMPK activator, Metformin, did not alter either the C17.2-NSC or E14-NSC undifferentiated state although both Metformin and AICAR can activate the AMPK pathway in NSC. Furthermore, overexpression of dominant-negative mutants of AMPK in C17.2-NSC was unable to block the gliogenic effects of AICAR. We also found AICAR could activate the Janus kinase (JAK) STAT3 pathway in both C17.2-NSC and E14-NSC but Metformin fails. JAK inhibitor I abolished the gliogenic effects of AICAR. Taken together, these results suggest that the astroglial differentiation effect of AICAR on neural stem cells was acting independently of AMPK and that the JAK-STAT3 pathway is essential for the gliogenic effect of AICAR.
  Yabing Chen , Xiaohong Wang , Lie Di , Guoping Fu , Yuhong Chen , Li Bai , Jianzhong Liu , Xu Feng , Jay M. McDonald , Sue Michalek , Yinghong He , Mei Yu , Yang-Xin Fu , Renren Wen , Hui Wu and Demin Wang
  Phospholipase Cγ2 (PLCγ2) is an important signaling effector of multiple receptors in the immune system. Here we show that PLCγ2-deficient mice displayed impaired lymph node organogenesis but normal splenic structure and Peyer`s patches. Receptor activator of NF-κB ligand (RANKL) is a tumor necrosis factor family cytokine and is essential for lymph node organogenesis. Importantly, PLCγ2 deficiency severely impaired RANKL signaling, resulting in marked reduction of RANKL-induced activation of MAPKs, p38 and JNK, but not ERK. The lack of PLCγ2 markedly diminished RANKL-induced activation of NF-κB, AP-1, and NFATc1. Moreover, PLCγ2 deficiency impaired RANKL-mediated biological function, leading to failure of the PLCγ2-deficient bone marrow macrophage precursors to differentiate into osteoclasts after RANKL stimulation. Re-introduction of PLCγ2 but not PLCγ1 restores RANKL-mediated osteoclast differentiation of PLCγ2-deficient bone marrow-derived monocyte/macrophage. Taken together, PLCγ2 is essential for RANK signaling, and its deficiency leads to defective lymph node organogenesis and osteoclast differentiation.
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