Reduced Threshold for Luminal Ca²⁺ Activation of RyR1 Underlies a Causal Mechanism of Porcine Malignant Hyperthermia

Dawei Jiang, Wenqian Chen, Jianmin Xiao, Ruiwu Wang, Huihui Kong, Peter P. Jones, Lin Zhang, Bradley Fruen and S. R. Wayne Chen

The Journal of Biological Chemistry 283 ( 30 ): 20813 - 20820 , 2008