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Articles by Sofia Maraki
Total Records ( 2 ) for Sofia Maraki
  Athanasia Christidou , Sofia Maraki , Zoe Gitti and Yiannis Tselentis
  The aim of this study was to present the epidemiological, clinical and microbiological data, as well as the management and the outcome of 13 patients with documented Pasteurella multocida infections, diagnosed in the University hospital of Crete, Greece, between 1993 and 2004. Most patients (62%) were >70 years of age. Respiratory tract infections were most commonly encountered (61.5%), followed by soft-tissue infections (30.8%) and septicemia (7.7 %). Underlying diseases included malignancies, bullous pemphigoid, mitral valve stenosis, coronary disease, chronic obstructive pulmonary disease and intracranial hemorrhage. Antibiotic sensitivity testing showed that all P. multocida isolates were susceptible to beta-lactams, quinolones, chloramphenicol, tetracycline and trimethoprim/sulfamethoxazole. Antibiotics were administered to all 13 patients and a clinical response was observed in 77% of them. The overall mortality rate was 23% (3/13) but only 15.4% (2/13) died from the infection. Although rare, P. multocida infections should be suspected in patients reporting animal exposure, particularly in those with chronic underlying diseases.
  Diamantis P. Kofteridis , George Samonis , Alexander D. Karatzanis , Georgios M. Fragiadakis , Constantinos A. Bourolias , Sofia Maraki , John A. Papadakis and George A. Velegrakis
  Upper Respiratory Tract Infections (URTIs) are the most frequent of the community with major social and financial impact. Hence, early and proper diagnosis is of utmost importance. Biomarkers such as the circulating levels of Procalcitonin (PCT) have been shown to be elevated in systemic bacterial infections, but remain relatively low in viral infections and inflammatory diseases and have been suggested as signals for the initiation of antimicrobial therapy. Experience evaluating the value of PCT as a marker of URTIs is limited. Approach: Forty patients with bacterial URTIs were studied in order to assess the role of PCT, measured by using the semi-quantitative test, as bacterial inflammation marker and to compare with other markers, such as C-Reactive Protein (CRP), White Blood Cell (WBC) counts and Polymorphonuclear (PMN) cell counts. Results: In all cases, 22 with tonsillopharyngitis, 10 with peritonsillar abscess and 8 with rhinosinusitis, PCT levels remained below detection limits. On the other hand, serum CRP levels strongly correlated with body temperature, WBC and PMN cell counts. Patients with rhinosinusitis were older than those with peritonsillar abscess, had lower body temperature than those with tonsillopharyngitis and had lower serum CRP levels than patients with either peritonsillar abscess or tonsillopharyngitis. Conclusion: Therefore CRP could be used as a marker to predict the severity of URTIs while PCT, although promising in cases of other severe bacterial infections, did not prove to be suitable for patients with less severe or localized infections, such as URTIs.
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