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Articles by Saeideh Momtaz
Total Records ( 3 ) for Saeideh Momtaz
  Saeideh Momtaz
  Not Available.
  Saeideh Momtaz and Mohammad Abdollahi
  Aging is an undeniable fact shadowing animal life but while it comes to human, aging affects all aspects of their physical and emotional abilities. Aging occurs by multi-stimuli which is affected by both environmental and internal conditions. During the past decade, remarkable recognition of cellular senescence and its related pathways has happened. The increased production and/or ineffective scavenging of oxidants in particular, Reactive Oxygen Species (ROS) play a critical role in cellular senescence. High reactivity of ROS determines chemical changes in virtually all cellular components, leading to senescence mostly via DNA damage. Present paper discusses the oxidative stress as the main cause of aging and the benefit of antioxidants. So far, more effective explorations are needed to decrease the deleterious effects of oxidative-stress-induced aging. This approach could be achieved through manipulations of antioxidant enzyme systems, development of drug therapies, manipulation of aging related genes and genetic manipulation of plant-based antioxidant resources.
  Saeideh Momtaz and Mohammad Abdollahi
  Since ancient, the genus Satureja L. is well recognized for its therapeutic values. Only recently, scientists have been aware of its new medicinal aspects. In our last review, we evaluated existing scientific data about this genus. Regarding ongoing reports and new multi-functional properties of this plant we were interested to update pharmacology of Satureja. Data were gathered using of scientific books, journals, articles and websites including Pubmed, Scopus and Google Scholar up to 25th April 2010. Of initial search, 1540 records were reviewed for inclusion or exclusion in study, of which 71 publications were included. Different species of Satureja are famous for their analgesic, antiseptic, antimicrobial, antiviral, antioxidant, antiproliferative, antiprotozoal, antifungal, antidiarrheal, anti-inflammatory, anti-nociceptive, anticholinesterase and vasodilatory activities. The valuable therapeutic aspects of this genus are mostly correlated to the existence of essential oils, flavonoids and triterpenoids. The combination of two or more subspecies acting by different mechanisms to produce a synergistic effect should be considered. Based on the conducted assessments so far, antibacterial, antifungal, antiviral, antioxidant, anti-diabetic, vasodilatory and analgesic activities are characterized as the most applicable properties of Satureja subspecies. Further studies are needed to confirm novel pharmacological aspects of this genus in both animal and human.
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