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Articles by S.I. Smith
Total Records ( 2 ) for S.I. Smith
  B.A. Adeniyi , C.C. Amajoyi and S.I. Smith
  Fifty-two multidrug resistant local uropathogenic Escherichia coli, Klebsiella spp., Proteus spp. and Pseudomonas spp. isolates were tested for susceptibility to 10 antimicrobial agents. Tetracycline (100.0%) and ampicillin (94.2%) showed the highest rates of resistance and ciprofloxacin (50.0%) demonstrated the lowest. The majority of the multiple drug resistant (MDR) isolates showing concurrent resistance to all 10 agents (n = 17) was a component of 32.7%. A total of 23 antimicrobial resistance patterns was observed. The predominant phenotype (32.7%) amongst the isolates included resistance to ciprofloxacin, cefuroxime, ceftriaxone, ampicillin, gentamicin, nalidixic acid, nitrofurantoin, co-trimoxazole, streptomycin and tetracycline. A 38.5% (n = 10) of the isolates were carrying plasmids of sizes estimated above 2.1 kb. After curing, most of the mutant strains lost their plasmids as was corroborated by their improved susceptibilities. Given that uropathogens are demonstrating increasing antimicrobial resistance, epidemiological investigation using the molecular characterization tools is highly necessary.
  O.O. Aboaba , S.I. Smith and F.O. Olude
  Sixteen preparation of the ethanol and aqueous extracts of four edible plants, Entada africana (bark),Terminalia avicennoides (bark),Mitragyna stipulosa (bark) Lannae acida (stem bark) were screened for their inhibitory effects on ten strains of E coli 0157:H7 (EHEC) using the agar diffusion method. It was shown that ethanol extracts of Entanda africana inhibited all the ten strains used, some extracts showed variable antibacterial activities while some others could not cause any inhibition. The minimum inhibitory concentration (MIC) of the potent extracts ranged from 1.56mg/ml to 50.00mg/ml while the minimum bacteriocidal concentration (MBC) was between 6.25mg/ml to 25.00mg/ml. Pytochemical screening of the extracts revealed that all contained saponin. Some showed presence of tannins and glycosides while alkaloid was not detected in all samples.
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