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Articles by S. Mishra
Total Records ( 4 ) for S. Mishra
  P. Mishra , M. Verma , V. Mishra , S. Mishra and G.K. Rai
  Amla fruit can range upto 950 mg/100 g which is said to be highest among all fruits next only to Barbados cherry. Being very astringent in taste it can not be consumed as raw by the consumer hence processing became essential. Present study was an effort to develop commercially acceptable ready to eat green Amla chutney. To optimize the quantity of pulps and salts to be added, Response Surface Methodology (RSM) was used. Statistical software Stat-Ease was used for statistical and graphical analysis of the experimental data. To consider all the responses simultaneously for optimization the RSM was used to compromise optimum conditions and it was found that the sensory scores were 7.35, 7.8 and 7.75 for color, flavor and overall acceptability corresponding to optimum conditions. Chutney having composition Amla pulp-65.59%, salt -8%, green chilli-3.31%, garlic paste-2.11% and coriander leave paste 18.89% was found optimum. Triplicates samples were prepared using the optimum conditions and were evaluated for all the responses, corresponding values for color flavor and overall acceptability were 7.91, 8.08 and 8.08 which were comparatively higher than the predicted value. Therefore, the said formulations were recommended for ready to eat chutney. For the preservation of Amla chutney, salt concentration was varied from 8 to 12% while Brix were varied from 20 to 50°B. REC having 25°B had only 10 days of shelf life while chutney of 35°B could be stored upto twenty days at refrigeration temperature. Chutney having 50°B could be stored up to two months without any significant change in the quality attributes of the chutney.
  V. Mudgal , N. Madaan , A. Mudgal and S. Mishra
  Polyphenols are substances of plant origin that occur in numerous fruits and vegetables, wine, tea, olive oil, chocolate and other cocoa products. They show antioxidant properties in vitro and many of their biological actions have been attributed to their intrinsic reducing capabilities. Research on the effects of dietary polyphenols on human health has developed considerably in the past 10 years. It strongly supports a role for polyphenols in the prevention of degenerative diseases, particularly cardiovascular diseases, osteoporosis, neurodegenerative, diabetes mellitus and cancers. The antioxidant properties of polyphenols have been widely studied, but it has become clear that the mechanisms of action of polyphenols go beyond the modulation of oxidative stress. Polyphenols are currently sold as nutritional supplements. Yet the scientific basis for the health claims for polyphenols is mostly weak. Results from in vitro studies are often directly translated into possible beneficial health effects in humans. However, in the body, polyphenols are quickly and easily converted into polyphenol metabolites. Presented review on Polyphenols and Health, offers an overview of the experimental, clinical and epidemiologic evidence of the effects of polyphenols on health.
  S. Mishra and S. Nanda
  Sperm DNA fragmentation is known to compromise male fertility. The data entail that sperm DNA damage can be efficiently treated with oral antioxidant administration during a relatively short time period. It is an understanding that the 2 types of DNA appear to be distinct and independently packaged molecules; however, research has demonstrated the symbiotic nature of these structures in contributing to male infertility. Data must continue to be gathered to establish strong correlations between traditional semen analysis parameters and sperm DNA integrity; this information remains controversial and useless in clinical practice until new techniques for the diagnosis and treatment of sperm DNA can be established. More modern technology must be employed to correlate such information into useful clinical knowledge. This study is the compilation of reports pertaining to research on sperm DNA biochemistry and molecular biology to establish an opinion that sperm DNA integrity is both extremely fragile and exceedingly important for male fertility.
  N. Mishra , N.S. Gill , A. Mishra , S. Mishra , A. Shukla and A. Upadhayay
  Medicinal plants have been traditionally used for the treatment and prevention of peptic ulcer. The present study was designed to investigate antioxidant and antiulcer potential of methanolic fruit extract of Prunus domestica. Antioxidant activity was measured by 1,1-diphenyl-2-picrylhydrazyl and hydrogen peroxide free radical scavenging method. The extract showed maximum scavenging activity i.e., 82.12±0.654 and 79.43±0.876 at 200 μg mL-1. Further the extract was evaluated for its anti-ulcerogenic activity by pyloric ligation model. The extract showed significant inhibition of ulcer i.e., 70.58% at 200 mg kg-1. The present study concludes that Prunus domestica fruit posses potent antioxidant and anti-ulcerogenic effect.
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